BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

382 related articles for article (PubMed ID: 33921638)

  • 21. MRE11 inhibition highlights a replication stress-dependent vulnerability of MYCN-driven tumors.
    Petroni M; Sardina F; Infante P; Bartolazzi A; Locatelli E; Fabretti F; Di Giulio S; Capalbo C; Cardinali B; Coppa A; Tessitore A; Colicchia V; Sahùn Roncero M; Belardinilli F; Di Marcotullio L; Soddu S; Comes Franchini M; Petricci E; Gulino A; Giannini G
    Cell Death Dis; 2018 Aug; 9(9):895. PubMed ID: 30166519
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Hsp90 inhibitor-mediated disruption of chaperone association of ATR with hsp90 sensitizes cancer cells to DNA damage.
    Ha K; Fiskus W; Rao R; Balusu R; Venkannagari S; Nalabothula NR; Bhalla KN
    Mol Cancer Ther; 2011 Jul; 10(7):1194-206. PubMed ID: 21566061
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Marek's Disease Virus Disables the ATR-Chk1 Pathway by Activating STAT3.
    Lian X; Bao C; Li X; Zhang X; Chen H; Jung YS; Qian Y
    J Virol; 2019 May; 93(9):. PubMed ID: 30787154
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Targeting radioresistant breast cancer cells by single agent CHK1 inhibitor via enhancing replication stress.
    Zhang Y; Lai J; Du Z; Gao J; Yang S; Gorityala S; Xiong X; Deng O; Ma Z; Yan C; Susana G; Xu Y; Zhang J
    Oncotarget; 2016 Jun; 7(23):34688-702. PubMed ID: 27167194
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Co-Inhibition of the DNA Damage Response and CHK1 Enhances Apoptosis of Neuroblastoma Cells.
    Ando K; Nakamura Y; Nagase H; Nakagawara A; Koshinaga T; Wada S; Makishima M
    Int J Mol Sci; 2019 Jul; 20(15):. PubMed ID: 31362335
    [TBL] [Abstract][Full Text] [Related]  

  • 26. EGFR signaling promotes resistance to CHK1 inhibitor prexasertib in triple negative breast cancer.
    Lee KJ; Wright G; Bryant H; Wiggins LA; Schuler M; Gassman NR
    Cancer Drug Resist; 2020; 3(4):980-991. PubMed ID: 35582228
    [No Abstract]   [Full Text] [Related]  

  • 27. Inhibition of Chk1 with the small molecule inhibitor V158411 induces DNA damage and cell death in an unperturbed S-phase.
    Wayne J; Brooks T; Massey AJ
    Oncotarget; 2016 Dec; 7(51):85033-85048. PubMed ID: 27829224
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Differential roles of checkpoint kinase 1, checkpoint kinase 2, and mitogen-activated protein kinase-activated protein kinase 2 in mediating DNA damage-induced cell cycle arrest: implications for cancer therapy.
    Xiao Z; Xue J; Sowin TJ; Zhang H
    Mol Cancer Ther; 2006 Aug; 5(8):1935-43. PubMed ID: 16928813
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Prevention of DNA Replication Stress by CHK1 Leads to Chemoresistance Despite a DNA Repair Defect in Homologous Recombination in Breast Cancer.
    Meyer F; Becker S; Classen S; Parplys AC; Mansour WY; Riepen B; Timm S; Ruebe C; Jasin M; Wikman H; Petersen C; Rothkamm K; Borgmann K
    Cells; 2020 Jan; 9(1):. PubMed ID: 31963582
    [TBL] [Abstract][Full Text] [Related]  

  • 30. LY2606368 Causes Replication Catastrophe and Antitumor Effects through CHK1-Dependent Mechanisms.
    King C; Diaz HB; McNeely S; Barnard D; Dempsey J; Blosser W; Beckmann R; Barda D; Marshall MS
    Mol Cancer Ther; 2015 Sep; 14(9):2004-13. PubMed ID: 26141948
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Cancer-Specific Synthetic Lethality between ATR and CHK1 Kinase Activities.
    Sanjiv K; Hagenkort A; Calderón-Montaño JM; Koolmeister T; Reaper PM; Mortusewicz O; Jacques SA; Kuiper RV; Schultz N; Scobie M; Charlton PA; Pollard JR; Berglund UW; Altun M; Helleday T
    Cell Rep; 2016 Jan; 14(2):298-309. PubMed ID: 26748709
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Targeting the cell cycle in head and neck cancer by Chk1 inhibition: a novel concept of bimodal cell death.
    van Harten AM; Buijze M; van der Mast R; Rooimans MA; Martens-de Kemp SR; Bachas C; Brink A; Stigter-van Walsum M; Wolthuis RMF; Brakenhoff RH
    Oncogenesis; 2019 Jun; 8(7):38. PubMed ID: 31209198
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Synthetic Lethal Targeting of Mitotic Checkpoints in HPV-Negative Head and Neck Cancer.
    Deneka AY; Einarson MB; Bennett J; Nikonova AS; Elmekawy M; Zhou Y; Lee JW; Burtness BA; Golemis EA
    Cancers (Basel); 2020 Jan; 12(2):. PubMed ID: 32012873
    [TBL] [Abstract][Full Text] [Related]  

  • 34. ATR-CHK1 pathway as a therapeutic target for acute and chronic leukemias.
    Boudny M; Trbusek M
    Cancer Treat Rev; 2020 Aug; 88():102026. PubMed ID: 32592909
    [TBL] [Abstract][Full Text] [Related]  

  • 35. SLFN11 Blocks Stressed Replication Forks Independently of ATR.
    Murai J; Tang SW; Leo E; Baechler SA; Redon CE; Zhang H; Al Abo M; Rajapakse VN; Nakamura E; Jenkins LMM; Aladjem MI; Pommier Y
    Mol Cell; 2018 Feb; 69(3):371-384.e6. PubMed ID: 29395061
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Rad51 Degradation: Role in Oncolytic Virus-Poly(ADP-Ribose) Polymerase Inhibitor Combination Therapy in Glioblastoma.
    Ning J; Wakimoto H; Peters C; Martuza RL; Rabkin SD
    J Natl Cancer Inst; 2017 Mar; 109(3):1-13. PubMed ID: 28376211
    [TBL] [Abstract][Full Text] [Related]  

  • 37. ATM, ATR, CHK1, CHK2 and WEE1 inhibitors in cancer and cancer stem cells.
    Ronco C; Martin AR; Demange L; Benhida R
    Medchemcomm; 2017 Feb; 8(2):295-319. PubMed ID: 30108746
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Targeting the Homologous Recombination Pathway in Cancer With a Novel Class of RAD51 Inhibitors.
    Gu P; Xue L; Zhao C; Li W; Jiang Z; Liu A; Li T; Liu L; Decker M; Cheng X; Yang W; Tang R
    Front Oncol; 2022; 12():885186. PubMed ID: 35646698
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Prostaglandin E2 Promotes Colorectal Cancer Stem Cell Expansion and Metastasis in Mice.
    Wang D; Fu L; Sun H; Guo L; DuBois RN
    Gastroenterology; 2015 Dec; 149(7):1884-1895.e4. PubMed ID: 26261008
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Extensive RPA2 hyperphosphorylation promotes apoptosis in response to DNA replication stress in CHK1 inhibited cells.
    Zuazua-Villar P; Ganesh A; Phear G; Gagou ME; Meuth M
    Nucleic Acids Res; 2015 Nov; 43(20):9776-87. PubMed ID: 26271993
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 20.