483 related articles for article (PubMed ID: 33921734)
1. Genistein Activates Transcription Factor EB and Corrects Niemann-Pick C Phenotype.
Argüello G; Balboa E; Tapia PJ; Castro J; Yañez MJ; Mattar P; Pulgar R; Zanlungo S
Int J Mol Sci; 2021 Apr; 22(8):. PubMed ID: 33921734
[TBL] [Abstract][Full Text] [Related]
2. Trehalose enhances mitochondria deficits in human NPC1 mutant fibroblasts but disrupts mouse Purkinje cell dendritic growth ex vivo.
MacLeod CM; Yousufzai FAK; Spencer LT; Kim S; Rivera-Rosario LA; Barrera ZD; Walsh L; Krummenacher C; Carone B; Soto I
PLoS One; 2023; 18(11):e0294312. PubMed ID: 38033125
[TBL] [Abstract][Full Text] [Related]
3. 2-Hydroxypropyl-gamma-cyclodextrin overcomes NPC1 deficiency by enhancing lysosome-ER association and autophagy.
Singhal A; Krystofiak ES; Jerome WG; Song B
Sci Rep; 2020 May; 10(1):8663. PubMed ID: 32457374
[TBL] [Abstract][Full Text] [Related]
4. β-Cyclodextrin-threaded biocleavable polyrotaxanes ameliorate impaired autophagic flux in Niemann-Pick type C disease.
Tamura A; Yui N
J Biol Chem; 2015 Apr; 290(15):9442-54. PubMed ID: 25713067
[TBL] [Abstract][Full Text] [Related]
5. Targeting defective sphingosine kinase 1 in Niemann-Pick type C disease with an activator mitigates cholesterol accumulation.
Newton J; Palladino END; Weigel C; Maceyka M; Gräler MH; Senkal CE; Enriz RD; Marvanova P; Jampilek J; Lima S; Milstien S; Spiegel S
J Biol Chem; 2020 Jul; 295(27):9121-9133. PubMed ID: 32385114
[TBL] [Abstract][Full Text] [Related]
6. Finding pathogenic commonalities between Niemann-Pick type C and other lysosomal storage disorders: Opportunities for shared therapeutic interventions.
Yañez MJ; Marín T; Balboa E; Klein AD; Alvarez AR; Zanlungo S
Biochim Biophys Acta Mol Basis Dis; 2020 Oct; 1866(10):165875. PubMed ID: 32522631
[TBL] [Abstract][Full Text] [Related]
7. Enrichment of NPC1-deficient cells with the lipid LBPA stimulates autophagy, improves lysosomal function, and reduces cholesterol storage.
Ilnytska O; Lai K; Gorshkov K; Schultz ML; Tran BN; Jeziorek M; Kunkel TJ; Azaria RD; McLoughlin HS; Waghalter M; Xu Y; Schlame M; Altan-Bonnet N; Zheng W; Lieberman AP; Dobrowolski R; Storch J
J Biol Chem; 2021 Jul; 297(1):100813. PubMed ID: 34023384
[TBL] [Abstract][Full Text] [Related]
8. Primary cilium alterations and expression changes of Patched1 proteins in niemann-pick type C disease.
Formichi P; Battisti C; De Santi MM; Guazzo R; Tripodi SA; Radi E; Rossi B; Tarquini E; Federico A
J Cell Physiol; 2018 Jan; 233(1):663-672. PubMed ID: 28332184
[TBL] [Abstract][Full Text] [Related]
9. Cytosolic glucosylceramide regulates endolysosomal function in Niemann-Pick type C disease.
Wheeler S; Haberkant P; Bhardwaj M; Tongue P; Ferraz MJ; Halter D; Sprong H; Schmid R; Aerts JMFG; Sullo N; Sillence DJ
Neurobiol Dis; 2019 Jul; 127():242-252. PubMed ID: 30872158
[TBL] [Abstract][Full Text] [Related]
10. Hydroxypropyl-beta and -gamma cyclodextrins rescue cholesterol accumulation in Niemann-Pick C1 mutant cell via lysosome-associated membrane protein 1.
Singhal A; Szente L; Hildreth JEK; Song B
Cell Death Dis; 2018 Oct; 9(10):1019. PubMed ID: 30282967
[TBL] [Abstract][Full Text] [Related]
11. Different Trafficking Phenotypes of Niemann-Pick C1 Gene Mutations Correlate with Various Alterations in Lipid Storage, Membrane Composition and Miglustat Amenability.
Brogden G; Shammas H; Walters F; Maalouf K; Das AM; Naim HY; Rizk S
Int J Mol Sci; 2020 Mar; 21(6):. PubMed ID: 32204338
[TBL] [Abstract][Full Text] [Related]
12. Beneficial effects of primidone in Niemann-Pick disease type C (NPC)-model cells and mice: Reduction of unesterified cholesterol levels in cells and extension of lifespan in mice.
Ashikawa H; Mogi H; Honda T; Nakamura H; Murayama T
Eur J Pharmacol; 2021 Apr; 896():173907. PubMed ID: 33503462
[TBL] [Abstract][Full Text] [Related]
13. δ-Tocopherol reduces lipid accumulation in Niemann-Pick type C1 and Wolman cholesterol storage disorders.
Xu M; Liu K; Swaroop M; Porter FD; Sidhu R; Firnkes S; Ory DS; Marugan JJ; Xiao J; Southall N; Pavan WJ; Davidson C; Walkley SU; Remaley AT; Baxa U; Sun W; McKew JC; Austin CP; Zheng W
J Biol Chem; 2012 Nov; 287(47):39349-60. PubMed ID: 23035117
[TBL] [Abstract][Full Text] [Related]
14. Analytical Characterization of Methyl-β-Cyclodextrin for Pharmacological Activity to Reduce Lysosomal Cholesterol Accumulation in Niemann-Pick Disease Type C1 Cells.
Li R; Hao J; Fujiwara H; Xu M; Yang S; Dai S; Long Y; Swaroop M; Li C; Vu M; Marugan JJ; Ory DS; Zheng W
Assay Drug Dev Technol; 2017; 15(4):154-166. PubMed ID: 28631941
[TBL] [Abstract][Full Text] [Related]
15. Niemann-Pick type C disease: cellular pathology and pharmacotherapy.
Wheeler S; Sillence DJ
J Neurochem; 2020 Jun; 153(6):674-692. PubMed ID: 31608980
[TBL] [Abstract][Full Text] [Related]
16. ABCA1-dependent mobilization of lysosomal cholesterol requires functional Niemann-Pick C2 but not Niemann-Pick C1 protein.
Boadu E; Nelson RC; Francis GA
Biochim Biophys Acta; 2012 Mar; 1821(3):396-404. PubMed ID: 22179027
[TBL] [Abstract][Full Text] [Related]
17. The stimulation of adenosine A2A receptors ameliorates the pathological phenotype of fibroblasts from Niemann-Pick type C patients.
Visentin S; De Nuccio C; Bernardo A; Pepponi R; Ferrante A; Minghetti L; Popoli P
J Neurosci; 2013 Sep; 33(39):15388-93. PubMed ID: 24068806
[TBL] [Abstract][Full Text] [Related]
18. The phytoestrogen genistein modulates lysosomal metabolism and transcription factor EB (TFEB) activation.
Moskot M; Montefusco S; Jakóbkiewicz-Banecka J; Mozolewski P; Węgrzyn A; Di Bernardo D; Węgrzyn G; Medina DL; Ballabio A; Gabig-Cimińska M
J Biol Chem; 2014 Jun; 289(24):17054-69. PubMed ID: 24770416
[TBL] [Abstract][Full Text] [Related]
19. High-content screen for modifiers of Niemann-Pick type C disease in patient cells.
Pugach EK; Feltes M; Kaufman RJ; Ory DS; Bang AG
Hum Mol Genet; 2018 Jun; 27(12):2101-2112. PubMed ID: 29659804
[TBL] [Abstract][Full Text] [Related]
20. Niemann-Pick disease type C1 is a sphingosine storage disease that causes deregulation of lysosomal calcium.
Lloyd-Evans E; Morgan AJ; He X; Smith DA; Elliot-Smith E; Sillence DJ; Churchill GC; Schuchman EH; Galione A; Platt FM
Nat Med; 2008 Nov; 14(11):1247-55. PubMed ID: 18953351
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]