196 related articles for article (PubMed ID: 33931701)
1. Serine protease dynamics revealed by NMR analysis of the thrombin-thrombomodulin complex.
Peacock RB; McGrann T; Tonelli M; Komives EA
Sci Rep; 2021 Apr; 11(1):9354. PubMed ID: 33931701
[TBL] [Abstract][Full Text] [Related]
2. Thrombomodulin Binding Selects the Catalytically Active Form of Thrombin.
Handley LD; Treuheit NA; Venkatesh VJ; Komives EA
Biochemistry; 2015 Nov; 54(43):6650-8. PubMed ID: 26468766
[TBL] [Abstract][Full Text] [Related]
3. How Thrombomodulin Enables W215A/E217A Thrombin to Cleave Protein C but Not Fibrinogen.
Peacock RB; McGrann T; Zaragoza S; Komives EA
Biochemistry; 2022 Jan; 61(2):77-84. PubMed ID: 34978431
[TBL] [Abstract][Full Text] [Related]
4. Identification of a thrombin-binding region in the sixth epidermal growth factor-like repeat of human thrombomodulin.
Tolkatchev D; Ng A; Zhu B; Ni F
Biochemistry; 2000 Aug; 39(34):10365-72. PubMed ID: 10956026
[TBL] [Abstract][Full Text] [Related]
5. Thrombomodulin tightens the thrombin active site loops to promote protein C activation.
Koeppe JR; Seitova A; Mather T; Komives EA
Biochemistry; 2005 Nov; 44(45):14784-91. PubMed ID: 16274226
[TBL] [Abstract][Full Text] [Related]
6. Probing the activation of protein C by the thrombin-thrombomodulin complex using structural analysis, site-directed mutagenesis, and computer modeling.
Knobe KE; Berntsdotter A; Shen L; Morser J; Dahlbäck B; Villoutreix BO
Proteins; 1999 May; 35(2):218-34. PubMed ID: 10223294
[TBL] [Abstract][Full Text] [Related]
7. Solvent accessibility of the thrombin-thrombomodulin interface.
Mandell JG; Baerga-Ortiz A; Akashi S; Takio K; Komives EA
J Mol Biol; 2001 Feb; 306(3):575-89. PubMed ID: 11178915
[TBL] [Abstract][Full Text] [Related]
8. Molecular basis of thrombomodulin activation of slow thrombin.
Adams TE; Li W; Huntington JA
J Thromb Haemost; 2009 Oct; 7(10):1688-95. PubMed ID: 19656282
[TBL] [Abstract][Full Text] [Related]
9. Conformational analysis of gamma' peptide (410-427) interactions with thrombin anion binding exosite II.
Sabo TM; Farrell DH; Maurer MC
Biochemistry; 2006 Jun; 45(24):7434-45. PubMed ID: 16768439
[TBL] [Abstract][Full Text] [Related]
10. Energetics of thrombin-thrombomodulin interaction.
Vindigni A; White CE; Komives EA; Di Cera E
Biochemistry; 1997 Jun; 36(22):6674-81. PubMed ID: 9184147
[TBL] [Abstract][Full Text] [Related]
11. Hydrogen/Deuterium Exchange and Nuclear Magnetic Resonance Spectroscopy Reveal Dynamic Allostery on Multiple Time Scales in the Serine Protease Thrombin.
Peacock RB; Komives EA
Biochemistry; 2021 Nov; 60(46):3441-3448. PubMed ID: 34159782
[TBL] [Abstract][Full Text] [Related]
12. Essential thrombin residues for inhibition by protein C inhibitor with the cofactors heparin and thrombomodulin.
Fortenberry YM; Whinna HC; Cooper ST; Myles T; Leung LL; Church FC
J Thromb Haemost; 2007 Jul; 5(7):1486-92. PubMed ID: 17635698
[TBL] [Abstract][Full Text] [Related]
13. Mutations in the fourth EGF-like domain affect thrombomodulin-induced changes in the active site of thrombin.
Koeppe JR; Beach MA; Baerga-Ortiz A; Kerns SJ; Komives EA
Biochemistry; 2008 Oct; 47(41):10933-9. PubMed ID: 18803401
[TBL] [Abstract][Full Text] [Related]
14. Thrombomodulin allosterically modulates the activity of the anticoagulant thrombin.
Rezaie AR; Yang L
Proc Natl Acad Sci U S A; 2003 Oct; 100(21):12051-6. PubMed ID: 14523228
[TBL] [Abstract][Full Text] [Related]
15. NMR reveals a dynamic allosteric pathway in thrombin.
Handley LD; Fuglestad B; Stearns K; Tonelli M; Fenwick RB; Markwick PR; Komives EA
Sci Rep; 2017 Jan; 7():39575. PubMed ID: 28059082
[TBL] [Abstract][Full Text] [Related]
16. Calcium-binding sites of the thrombin-thrombomodulin-protein C complex: possible implications for the effect of platelet factor 4 on the activation of vitamin K-dependent coagulation factors.
Yang L; Rezaie AR
Thromb Haemost; 2007 Jun; 97(6):899-906. PubMed ID: 17549291
[TBL] [Abstract][Full Text] [Related]
17. Activation of protein C by the thrombin-thrombomodulin complex: cooperative roles of Arg-35 of thrombin and Arg-67 of protein C.
Yang L; Manithody C; Rezaie AR
Proc Natl Acad Sci U S A; 2006 Jan; 103(4):879-84. PubMed ID: 16418283
[TBL] [Abstract][Full Text] [Related]
18. The effects of exosite occupancy on the substrate specificity of thrombin.
Ng NM; Quinsey NS; Matthews AY; Kaiserman D; Wijeyewickrema LC; Bird PI; Thompson PE; Pike RN
Arch Biochem Biophys; 2009 Sep; 489(1-2):48-54. PubMed ID: 19638274
[TBL] [Abstract][Full Text] [Related]
19. NMR resonance assignments of thrombin reveal the conformational and dynamic effects of ligation.
Lechtenberg BC; Johnson DJ; Freund SM; Huntington JA
Proc Natl Acad Sci U S A; 2010 Aug; 107(32):14087-92. PubMed ID: 20660315
[TBL] [Abstract][Full Text] [Related]
20. Thrombin cleaves and activates the protease-activated receptor 2 dependent on thrombomodulin co-receptor availability.
Heuberger DM; Franchini AG; Madon J; Schuepbach RA
Thromb Res; 2019 May; 177():91-101. PubMed ID: 30861432
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]