299 related articles for article (PubMed ID: 33941661)
41. Covalent and allosteric inhibitors of the ATPase VCP/p97 induce cancer cell death.
Magnaghi P; D'Alessio R; Valsasina B; Avanzi N; Rizzi S; Asa D; Gasparri F; Cozzi L; Cucchi U; Orrenius C; Polucci P; Ballinari D; Perrera C; Leone A; Cervi G; Casale E; Xiao Y; Wong C; Anderson DJ; Galvani A; Donati D; O'Brien T; Jackson PK; Isacchi A
Nat Chem Biol; 2013 Sep; 9(9):548-56. PubMed ID: 23892893
[TBL] [Abstract][Full Text] [Related]
42. Genotoxic effects of topoisomerase poisoning and PARP inhibition on zebrafish embryos.
Karapetian M; Tsikarishvili S; Kulikova N; Kurdadze A; Zaalishvili G
DNA Repair (Amst); 2020 Mar; 87():102772. PubMed ID: 31877465
[TBL] [Abstract][Full Text] [Related]
43. Replication-dependent and transcription-dependent mechanisms of DNA double-strand break induction by the topoisomerase 2-targeting drug etoposide.
Tammaro M; Barr P; Ricci B; Yan H
PLoS One; 2013; 8(11):e79202. PubMed ID: 24244448
[TBL] [Abstract][Full Text] [Related]
44. RAD54L2-mediated DNA damage avoidance pathway specifically preserves genome integrity in response to topoisomerase 2 poisons.
Zhang H; Xiong Y; Sun Y; Park JM; Su D; Feng X; Keast S; Tang M; Huang M; Wang C; Srivastava M; Yang C; Zhu D; Chen Z; Li S; Yin L; Pommier Y; Chen J
Sci Adv; 2023 Dec; 9(49):eadi6681. PubMed ID: 38055811
[TBL] [Abstract][Full Text] [Related]
45. Tyrosyl-DNA-phosphodiesterase I (TDP1) participates in the removal and repair of stabilized-Top2α cleavage complexes in human cells.
Borda MA; Palmitelli M; Verón G; González-Cid M; de Campos Nebel M
Mutat Res; 2015 Nov; 781():37-48. PubMed ID: 26421495
[TBL] [Abstract][Full Text] [Related]
46. Proteolytic degradation of topoisomerase II (Top2) enables the processing of Top2·DNA and Top2·RNA covalent complexes by tyrosyl-DNA-phosphodiesterase 2 (TDP2).
Gao R; Schellenberg MJ; Huang SY; Abdelmalak M; Marchand C; Nitiss KC; Nitiss JL; Williams RS; Pommier Y
J Biol Chem; 2014 Jun; 289(26):17960-9. PubMed ID: 24808172
[TBL] [Abstract][Full Text] [Related]
47. NMS-873 functions as a dual inhibitor of mitochondrial oxidative phosphorylation.
Bouwer MF; Hamilton KE; Jonker PB; Kuiper SR; Louters LL; Looyenga BD
Biochimie; 2021 Jun; 185():33-42. PubMed ID: 33727138
[TBL] [Abstract][Full Text] [Related]
48. MDM2 provides TOP2 poison resistance by promoting proteolysis of TOP2βcc in a p53-independent manner.
Shu J; Jiang J; Wang X; Yang X; Zhao G; Cai T
Cell Death Dis; 2024 Jan; 15(1):83. PubMed ID: 38263255
[TBL] [Abstract][Full Text] [Related]
49. TDP2 suppresses chromosomal translocations induced by DNA topoisomerase II during gene transcription.
Gómez-Herreros F; Zagnoli-Vieira G; Ntai I; Martínez-Macías MI; Anderson RM; Herrero-Ruíz A; Caldecott KW
Nat Commun; 2017 Aug; 8(1):233. PubMed ID: 28794467
[TBL] [Abstract][Full Text] [Related]
50. DNA-PK inhibition extends the therapeutic effects of Top2 poisoning to non-proliferating cells, increasing activity at a cost.
Wang T; Kyle AH; Baker JHE; Liu NA; Banáth JP; Minchinton AI
Sci Rep; 2023 Aug; 13(1):12429. PubMed ID: 37528151
[TBL] [Abstract][Full Text] [Related]
51. The ATP-dependent chromatin remodelling enzyme Uls1 prevents Topoisomerase II poisoning.
Swanston A; Zabrady K; Ferreira HC
Nucleic Acids Res; 2019 Jul; 47(12):6172-6183. PubMed ID: 31106359
[TBL] [Abstract][Full Text] [Related]
52. TDP2/TTRAP is the major 5'-tyrosyl DNA phosphodiesterase activity in vertebrate cells and is critical for cellular resistance to topoisomerase II-induced DNA damage.
Zeng Z; Cortés-Ledesma F; El Khamisy SF; Caldecott KW
J Biol Chem; 2011 Jan; 286(1):403-9. PubMed ID: 21030584
[TBL] [Abstract][Full Text] [Related]
53. Tyrosyl-DNA phosphodiesterase (Tdp1) participates in the repair of Top2-mediated DNA damage.
Nitiss KC; Malik M; He X; White SW; Nitiss JL
Proc Natl Acad Sci U S A; 2006 Jun; 103(24):8953-8. PubMed ID: 16751265
[TBL] [Abstract][Full Text] [Related]
54. Clarifying the Mechanism of Copper(II) α-(N)-Heterocyclic Thiosemicarbazone Complexes on DNA Topoisomerase IIα and IIβ.
Keck JM; Conner JD; Wilson JT; Jiang X; Lisic EC; Deweese JE
Chem Res Toxicol; 2019 Oct; 32(10):2135-2143. PubMed ID: 31512855
[TBL] [Abstract][Full Text] [Related]
55. Interaction between the AAA
Rao MV; Williams DR; Cocklin S; Loll PJ
J Biol Chem; 2017 Nov; 292(45):18392-18407. PubMed ID: 28939772
[TBL] [Abstract][Full Text] [Related]
56. Transcription-associated topoisomerase 2α (TOP2A) activity is a major effector of cytotoxicity induced by G-quadruplex ligands.
Bossaert M; Pipier A; Riou JF; Noirot C; Nguyên LT; Serre RF; Bouchez O; Defrancq E; Calsou P; Britton S; Gomez D
Elife; 2021 Jun; 10():. PubMed ID: 34180392
[TBL] [Abstract][Full Text] [Related]
57. AAA ATPase p97/valosin-containing protein interacts with gp78, a ubiquitin ligase for endoplasmic reticulum-associated degradation.
Zhong X; Shen Y; Ballar P; Apostolou A; Agami R; Fang S
J Biol Chem; 2004 Oct; 279(44):45676-84. PubMed ID: 15331598
[TBL] [Abstract][Full Text] [Related]
58. Isolation and characterization of mAMSA-hypersensitive mutants. Cytotoxicity of Top2 covalent complexes containing DNA single strand breaks.
Rogojina AT; Nitiss JL
J Biol Chem; 2008 Oct; 283(43):29239-50. PubMed ID: 18723844
[TBL] [Abstract][Full Text] [Related]
59. The Human Cytomegalovirus Transmembrane Protein pUL50 Induces Loss of VCP/p97 and Is Regulated by a Small Isoform of pUL50.
Lee MK; Hyeon S; Ahn JH
J Virol; 2020 Jun; 94(13):. PubMed ID: 32321808
[TBL] [Abstract][Full Text] [Related]
60. ATP-binding sites in brain p97/VCP (valosin-containing protein), a multifunctional AAA ATPase.
Zalk R; Shoshan-Barmatz V
Biochem J; 2003 Sep; 374(Pt 2):473-80. PubMed ID: 12747802
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]