BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

140 related articles for article (PubMed ID: 33964933)

  • 1. A somatic mutation in PIK3CD unravels a novel candidate gene for lymphatic malformation.
    Wang S; Wang W; Zhang X; Gui J; Zhang J; Guo Y; Liu Y; Han L; Liu Q; Li Y; Sun N; Liu Z; Du J; Tai J; Ni X
    Orphanet J Rare Dis; 2021 May; 16(1):208. PubMed ID: 33964933
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Blockade of VEGF-C signaling inhibits lymphatic malformations driven by oncogenic PIK3CA mutation.
    Martinez-Corral I; Zhang Y; Petkova M; Ortsäter H; Sjöberg S; Castillo SD; Brouillard P; Libbrecht L; Saur D; Graupera M; Alitalo K; Boon L; Vikkula M; Mäkinen T
    Nat Commun; 2020 Jun; 11(1):2869. PubMed ID: 32513927
    [TBL] [Abstract][Full Text] [Related]  

  • 3. PIK3CA mutations are specifically localized to lymphatic endothelial cells of lymphatic malformations.
    Blesinger H; Kaulfuß S; Aung T; Schwoch S; Prantl L; Rößler J; Wilting J; Becker J
    PLoS One; 2018; 13(7):e0200343. PubMed ID: 29985963
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Linkage of Metabolic Defects to Activated PIK3CA Alleles in Endothelial Cells Derived from Lymphatic Malformation.
    Glaser K; Dickie P; Neilson D; Osborn A; Dickie BH
    Lymphat Res Biol; 2018 Feb; 16(1):43-55. PubMed ID: 29346025
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A novel method for isolating lymphatic endothelial cells from lymphatic malformations and detecting PIK3CA somatic mutation in these isolated cells.
    Usui H; Tsurusaki Y; Shimbo H; Saitsu H; Harada N; Kitagawa N; Mochizuki K; Masuda M; Kurosawa K; Shinkai M
    Surg Today; 2021 Mar; 51(3):439-446. PubMed ID: 32876734
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Non-hotspot PIK3CA mutations are more frequent in CLOVES than in common or combined lymphatic malformations.
    Brouillard P; Schlögel MJ; Homayun Sepehr N; Helaers R; Queisser A; Fastré E; Boutry S; Schmitz S; Clapuyt P; Hammer F; Dompmartin A; Weitz-Tuoretmaa A; Laranne J; Pasquesoone L; Vilain C; Boon LM; Vikkula M
    Orphanet J Rare Dis; 2021 Jun; 16(1):267. PubMed ID: 34112235
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Activating PIK3CA alleles and lymphangiogenic phenotype of lymphatic endothelial cells isolated from lymphatic malformations.
    Osborn AJ; Dickie P; Neilson DE; Glaser K; Lynch KA; Gupta A; Dickie BH
    Hum Mol Genet; 2015 Feb; 24(4):926-38. PubMed ID: 25292196
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Lymphatic and other vascular malformative/overgrowth disorders are caused by somatic mutations in PIK3CA.
    Luks VL; Kamitaki N; Vivero MP; Uller W; Rab R; Bovée JV; Rialon KL; Guevara CJ; Alomari AI; Greene AK; Fishman SJ; Kozakewich HP; Maclellan RA; Mulliken JB; Rahbar R; Spencer SA; Trenor CC; Upton J; Zurakowski D; Perkins JA; Kirsh A; Bennett JT; Dobyns WB; Kurek KC; Warman ML; McCarroll SA; Murillo R
    J Pediatr; 2015 Apr; 166(4):1048-54.e1-5. PubMed ID: 25681199
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Genotype correlates with clinical severity in PIK3CA-associated lymphatic malformations.
    Zenner K; Cheng CV; Jensen DM; Timms AE; Shivaram G; Bly R; Ganti S; Whitlock KB; Dobyns WB; Perkins J; Bennett JT
    JCI Insight; 2019 Nov; 4(21):. PubMed ID: 31536475
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Microcystic lymphatic malformations in Turner syndrome are due to somatic mosaicism of PIK3CA.
    Nriagu BN; Williams LS; Brewer N; Surrey LF; Srinivasan AS; Li D; Britt A; Treat J; Crowley TB; O'Connor N; Ganguly A; Low D; Queenan M; Drivas TG; Zackai EH; Adams DM; Hakonarson H; Snyder KM; Sheppard SE
    Am J Med Genet A; 2024 Jan; 194(1):64-69. PubMed ID: 37705207
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The YAP signaling pathway promotes the progression of lymphatic malformations through the activation of lymphatic endothelial cells.
    Zhong W; Jiang H; Zou Y; Ren J; Li Z; He K; Zhao J; Zhou X; Mou D; Cai Y
    Pediatr Res; 2021 Jan; 89(1):110-117. PubMed ID: 32279070
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Somatic frameshift mutation in PIK3CA causes CLOVES syndrome by provoking PI3K/AKT/mTOR pathway.
    Yan W; Zhang B; Wang H; Mo R; Jiang X; Qin W; Ma L; Lin Z
    Hereditas; 2021 Jun; 158(1):18. PubMed ID: 34074347
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Constitutively active PIK3CA mutations are expressed by lymphatic and vascular endothelial cells in capillary lymphatic venous malformation.
    Le Cras TD; Goines J; Lakes N; Pastura P; Hammill AM; Adams DM; Boscolo E
    Angiogenesis; 2020 Aug; 23(3):425-442. PubMed ID: 32350708
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Somatic Activating PIK3CA Mutations Cause Venous Malformation.
    Limaye N; Kangas J; Mendola A; Godfraind C; Schlögel MJ; Helaers R; Eklund L; Boon LM; Vikkula M
    Am J Hum Genet; 2015 Dec; 97(6):914-21. PubMed ID: 26637981
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The role of key biomarkers in lymphatic malformation: An updated review.
    Modaghegh MHS; Tanzadehpanah H; Kamyar MM; Manoochehri H; Sheykhhasan M; Forouzanfar F; Mahmoudian RA; Lotfian E; Mahaki H
    J Gene Med; 2024 Feb; 26(2):e3665. PubMed ID: 38375969
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Genomic landscape of lymphatic malformations: a case series and response to the PI3Kα inhibitor alpelisib in an
    Shaheen MF; Tse JY; Sokol ES; Masterson M; Bansal P; Rabinowitz I; Tarleton CA; Dobroff AS; Smith TL; Bocklage TJ; Mannakee BK; Gutenkunst RN; Bischoff J; Ness SA; Riedlinger GM; Groisberg R; Pasqualini R; Ganesan S; Arap W
    Elife; 2022 Jul; 11():. PubMed ID: 35787784
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Down-regulation of polycystin in lymphatic malformations: possible role in the proliferation of lymphatic endothelial cells.
    Ren JG; Xia HF; Yang JG; Zhu JY; Zhang W; Chen G; Zhao JH; Sun YF; Zhao YF
    Hum Pathol; 2017 Jul; 65():231-238. PubMed ID: 28552828
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The mTOR Signal Pathway Is Overactivated in Human Lymphatic Malformations.
    Wang Q; Wang J; Wang M; Xu Y; Xu MN; Yuan SM
    Lymphat Res Biol; 2019 Dec; 17(6):624-629. PubMed ID: 31381473
    [No Abstract]   [Full Text] [Related]  

  • 19. Characterization of lymphatic malformations using primary cells and tissue transcriptomes.
    Kaipainen A; Chen E; Chang L; Zhao B; Shin H; Stahl A; Fishman SJ; Mulliken JB; Folkman J; Huang S; Fannon M
    Scand J Immunol; 2019 Oct; 90(4):e12800. PubMed ID: 31241785
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Somatic activating mutations in
    Rodriguez-Laguna L; Agra N; Ibañez K; Oliva-Molina G; Gordo G; Khurana N; Hominick D; Beato M; Colmenero I; Herranz G; Torres Canizalez JM; Rodríguez Pena R; Vallespín E; Martín-Arenas R; Del Pozo Á; Villaverde C; Bustamante A; Ayuso C; Lapunzina P; Lopez-Gutierrez JC; Dellinger MT; Martinez-Glez V
    J Exp Med; 2019 Feb; 216(2):407-418. PubMed ID: 30591517
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.