BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

270 related articles for article (PubMed ID: 33975179)

  • 1. XPO1 inhibition with selinexor synergizes with proteasome inhibition in neuroblastoma by targeting nuclear export of IkB.
    Galinski B; Luxemburg M; Landesman Y; Pawel B; Johnson KJ; Master SR; Freeman KW; Loeb DM; Hébert JM; Weiser DA
    Transl Oncol; 2021 Aug; 14(8):101114. PubMed ID: 33975179
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Proteomics identify nuclear export as a targetable pathway in neuroblastoma: Comment on "XPO1 inhibition with selinexor synergizes with proteasome inhibition in neuroblastoma by targeting nuclear export of IκB".
    Shah N
    Transl Oncol; 2021 Aug; 14(8):101150. PubMed ID: 34107420
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Selinexor, a Selective Inhibitor of Nuclear Export (SINE) compound, acts through NF-κB deactivation and combines with proteasome inhibitors to synergistically induce tumor cell death.
    Kashyap T; Argueta C; Aboukameel A; Unger TJ; Klebanov B; Mohammad RM; Muqbil I; Azmi AS; Drolen C; Senapedis W; Lee M; Kauffman M; Shacham S; Landesman Y
    Oncotarget; 2016 Nov; 7(48):78883-78895. PubMed ID: 27713151
    [TBL] [Abstract][Full Text] [Related]  

  • 4. XPO1 inhibitor combination therapy with bortezomib or carfilzomib induces nuclear localization of IκBα and overcomes acquired proteasome inhibitor resistance in human multiple myeloma.
    Turner JG; Kashyap T; Dawson JL; Gomez J; Bauer AA; Grant S; Dai Y; Shain KH; Meads M; Landesman Y; Sullivan DM
    Oncotarget; 2016 Nov; 7(48):78896-78909. PubMed ID: 27806331
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A method for quantification of exportin-1 (XPO1) occupancy by Selective Inhibitor of Nuclear Export (SINE) compounds.
    Crochiere ML; Baloglu E; Klebanov B; Donovan S; Del Alamo D; Lee M; Kauffman M; Shacham S; Landesman Y
    Oncotarget; 2016 Jan; 7(2):1863-77. PubMed ID: 26654943
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Anti-tumor efficacy of Selinexor (KPT-330) in gastric cancer is dependent on nuclear accumulation of p53 tumor suppressor.
    Subhash VV; Yeo MS; Wang L; Tan SH; Wong FY; Thuya WL; Tan WL; Peethala PC; Soe MY; Tan DSP; Padmanabhan N; Baloglu E; Shacham S; Tan P; Koeffler HP; Yong WP
    Sci Rep; 2018 Aug; 8(1):12248. PubMed ID: 30115935
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Treatment of acquired drug resistance in multiple myeloma by combination therapy with XPO1 and topoisomerase II inhibitors.
    Turner JG; Dawson JL; Grant S; Shain KH; Dalton WS; Dai Y; Meads M; Baz R; Kauffman M; Shacham S; Sullivan DM
    J Hematol Oncol; 2016 Aug; 9(1):73. PubMed ID: 27557643
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Exportin 1 Inhibition Induces Nerve Growth Factor Receptor Expression to Inhibit the NF-κB Pathway in Preclinical Models of Pediatric High-Grade Glioma.
    DeSisto JA; Flannery P; Lemma R; Pathak A; Mestnik S; Philips N; Bales NJ; Kashyap T; Moroze E; Venkataraman S; Kung AL; Carter BD; Landesman Y; Vibhakar R; Green AL
    Mol Cancer Ther; 2020 Feb; 19(2):540-551. PubMed ID: 31594826
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Selinexor inhibits growth of patient derived chordomas
    Walker CJ; Chang H; Henegar L; Kashyap T; Shacham S; Sommer J; Wick MJ; Levy J; Landesman Y
    Front Oncol; 2022; 12():808021. PubMed ID: 36059685
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Prognostic value and therapeutic targeting of XPO1 in chronic lymphocytic leukemia.
    Xu Z; Pan B; Miao Y; Li Y; Qin S; Liang J; Kong Y; Zhang X; Tang J; Xia Y; Zhu H; Wang L; Li J; Wu J; Xu W
    Clin Exp Med; 2023 Oct; 23(6):2651-2662. PubMed ID: 36738306
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Selinexor Overcomes Hypoxia-Induced Drug Resistance in Multiple Myeloma.
    Muz B; Azab F; de la Puente P; Landesman Y; Azab AK
    Transl Oncol; 2017 Aug; 10(4):632-640. PubMed ID: 28668761
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Therapeutic Targeting of Exportin-1 in Childhood Cancer.
    Galinski B; Alexander TB; Mitchell DA; Chatwin HV; Awah C; Green AL; Weiser DA
    Cancers (Basel); 2021 Dec; 13(24):. PubMed ID: 34944778
    [TBL] [Abstract][Full Text] [Related]  

  • 13. E3 ubiquitin ligase ASB8 promotes selinexor-induced proteasomal degradation of XPO1.
    Kwanten B; Deconick T; Walker C; Wang F; Landesman Y; Daelemans D
    Biomed Pharmacother; 2023 Apr; 160():114305. PubMed ID: 36731340
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Combining selinexor with alisertib to target the p53 pathway in neuroblastoma.
    Nguyen R; Wang H; Sun M; Lee DG; Peng J; Thiele CJ
    Neoplasia; 2022 Apr; 26():100776. PubMed ID: 35217309
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Nuclear export inhibitor Selinexor targeting XPO1 enhances coronavirus replication.
    Rahman MM; Estifanos B; Glenn HL; Kibler K; Li Y; Jacobs B; McFadden G; Hogue BG
    bioRxiv; 2023 Feb; ():. PubMed ID: 36824761
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Selinexor (KPT-330) has antitumor activity against anaplastic thyroid carcinoma in vitro and in vivo and enhances sensitivity to doxorubicin.
    Garg M; Kanojia D; Mayakonda A; Ganesan TS; Sadhanandhan B; Suresh S; S S; Nagare RP; Said JW; Doan NB; Ding LW; Baloglu E; Shacham S; Kauffman M; Koeffler HP
    Sci Rep; 2017 Aug; 7(1):9749. PubMed ID: 28852098
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The Nuclear Export Inhibitor Selinexor Inhibits Hypoxia Signaling Pathways And 3D Spheroid Growth Of Cancer Cells.
    Depping R; von Fallois M; Landesman Y; Kosyna FK
    Onco Targets Ther; 2019; 12():8387-8399. PubMed ID: 31632086
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Anti-tumor activity of selective inhibitor of nuclear export (SINE) compounds, is enhanced in non-Hodgkin lymphoma through combination with mTOR inhibitor and dexamethasone.
    Muqbil I; Aboukameel A; Elloul S; Carlson R; Senapedis W; Baloglu E; Kauffman M; Shacham S; Bhutani D; Zonder J; Azmi AS; Mohammad RM
    Cancer Lett; 2016 Dec; 383(2):309-317. PubMed ID: 27693556
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Guidance for Use and dosing of Selinexor in Multiple Myeloma in 2021: Consensus From International Myeloma Foundation Expert Roundtable.
    Nooka AK; Costa LJ; Gasparetto CJ; Richardson PG; Siegel DS; Chari A; Lentzsch S; Jagannath S; Mikhael J
    Clin Lymphoma Myeloma Leuk; 2022 Jul; 22(7):e526-e531. PubMed ID: 35361554
    [TBL] [Abstract][Full Text] [Related]  

  • 20. XPO1 target occupancy measurements confirm the selinexor recommended phase 2 dose.
    Crochiere ML; Hannus S; Hansen K; Becker F; Baloglu E; Lee M; Kauffman M; Shacham S; Landesman Y
    Oncotarget; 2017 Dec; 8(66):110503-110516. PubMed ID: 29299164
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.