These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
2. Probing the GTPase cycle with real-time NMR: GAP and GEF activities in cell extracts. Marshall CB; Meiri D; Smith MJ; Mazhab-Jafari MT; Gasmi-Seabrook GM; Rottapel R; Stambolic V; Ikura M Methods; 2012 Aug; 57(4):473-85. PubMed ID: 22750304 [TBL] [Abstract][Full Text] [Related]
3. Conformational resolution of nucleotide cycling and effector interactions for multiple small GTPases determined in parallel. Killoran RC; Smith MJ J Biol Chem; 2019 Jun; 294(25):9937-9948. PubMed ID: 31088913 [TBL] [Abstract][Full Text] [Related]
4. Real-Time Monitoring of RAS Activity Using In Vitro and In-Cell NMR Spectroscopy. Zhao Q; Shimada I; Nishida N Methods Mol Biol; 2024; 2797():237-252. PubMed ID: 38570464 [TBL] [Abstract][Full Text] [Related]
5. High-Throughput Dual Screening Method for Ras Activities and Inhibitors. Kopra K; van Adrichem AJ; Salo-Ahen OMH; Peltonen J; Wennerberg K; Härmä H Anal Chem; 2017 Apr; 89(8):4508-4516. PubMed ID: 28318223 [TBL] [Abstract][Full Text] [Related]
6. The small GTPases Ras and Rheb studied by multidimensional NMR spectroscopy: structure and function. Schöpel M; Potheraveedu VN; Al-Harthy T; Abdel-Jalil R; Heumann R; Stoll R Biol Chem; 2017 May; 398(5-6):577-588. PubMed ID: 28475102 [TBL] [Abstract][Full Text] [Related]
7. Regulation of small GTPases by GEFs, GAPs, and GDIs. Cherfils J; Zeghouf M Physiol Rev; 2013 Jan; 93(1):269-309. PubMed ID: 23303910 [TBL] [Abstract][Full Text] [Related]
8. κB-Ras proteins are fast-exchanging GTPases and function via nucleotide-independent binding of Ral GTPase-activating protein complexes. Rasche R; Apken LH; Michalke E; Kümmel D; Oeckinghaus A FEBS Lett; 2024 Jul; 598(14):1769-1782. PubMed ID: 38604989 [TBL] [Abstract][Full Text] [Related]
9. GEFs, GAPs, GDIs and effectors: taking a closer (3D) look at the regulation of Ras-related GTP-binding proteins. Geyer M; Wittinghofer A Curr Opin Struct Biol; 1997 Dec; 7(6):786-92. PubMed ID: 9434896 [TBL] [Abstract][Full Text] [Related]
10. Signaling interplay in Ras superfamily function. Mitin N; Rossman KL; Der CJ Curr Biol; 2005 Jul; 15(14):R563-74. PubMed ID: 16051167 [TBL] [Abstract][Full Text] [Related]
11. Involvement of the switch 2 domain of Ras in its interaction with guanine nucleotide exchange factors. Quilliam LA; Hisaka MM; Zhong S; Lowry A; Mosteller RD; Han J; Drugan JK; Broek D; Campbell SL; Der CJ J Biol Chem; 1996 May; 271(19):11076-82. PubMed ID: 8626650 [TBL] [Abstract][Full Text] [Related]
12. The role of Mg2+ cofactor in the guanine nucleotide exchange and GTP hydrolysis reactions of Rho family GTP-binding proteins. Zhang B; Zhang Y; Wang Z; Zheng Y J Biol Chem; 2000 Aug; 275(33):25299-307. PubMed ID: 10843989 [TBL] [Abstract][Full Text] [Related]
13. Control of Ras cycling by Ca2+. Walker SA; Cullen PJ; Taylor JA; Lockyer PJ FEBS Lett; 2003 Jul; 546(1):6-10. PubMed ID: 12829229 [TBL] [Abstract][Full Text] [Related]
15. p190RhoGAPs, the Héraud C; Pinault M; Lagrée V; Moreau V Cells; 2019 Apr; 8(4):. PubMed ID: 31013840 [TBL] [Abstract][Full Text] [Related]
16. Mechanism of the guanine nucleotide exchange reaction of Ras GTPase--evidence for a GTP/GDP displacement model. Zhang B; Zhang Y; Shacter E; Zheng Y Biochemistry; 2005 Feb; 44(7):2566-76. PubMed ID: 15709769 [TBL] [Abstract][Full Text] [Related]
17. Ras activation revisited: role of GEF and GAP systems. Hennig A; Markwart R; Esparza-Franco MA; Ladds G; Rubio I Biol Chem; 2015 Aug; 396(8):831-48. PubMed ID: 25781681 [TBL] [Abstract][Full Text] [Related]
18. Real-time NMR study of three small GTPases reveals that fluorescent 2'(3')-O-(N-methylanthraniloyl)-tagged nucleotides alter hydrolysis and exchange kinetics. Mazhab-Jafari MT; Marshall CB; Smith M; Gasmi-Seabrook GM; Stambolic V; Rottapel R; Neel BG; Ikura M J Biol Chem; 2010 Feb; 285(8):5132-6. PubMed ID: 20018863 [TBL] [Abstract][Full Text] [Related]
19. In vitro GEF and GAP assays. Eberth A; Ahmadian MR Curr Protoc Cell Biol; 2009 Jun; Chapter 14():Unit 14.9. PubMed ID: 19499504 [TBL] [Abstract][Full Text] [Related]
20. Conformational states of Ras complexed with the GTP analogue GppNHp or GppCH2p: implications for the interaction with effector proteins. Spoerner M; Nuehs A; Ganser P; Herrmann C; Wittinghofer A; Kalbitzer HR Biochemistry; 2005 Feb; 44(6):2225-36. PubMed ID: 15697248 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]