BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

200 related articles for article (PubMed ID: 33978412)

  • 1. Normal Mode Analysis of KRas4B Reveals Partner Specific Dynamics.
    Eren M; Tuncbag N; Jang H; Nussinov R; Gursoy A; Keskin O
    J Phys Chem B; 2021 May; 125(20):5210-5221. PubMed ID: 33978412
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Allosteric KRas4B Can Modulate SOS1 Fast and Slow Ras Activation Cycles.
    Liao TJ; Jang H; Fushman D; Nussinov R
    Biophys J; 2018 Aug; 115(4):629-641. PubMed ID: 30097175
    [TBL] [Abstract][Full Text] [Related]  

  • 3. PIP2 Influences the Conformational Dynamics of Membrane-Bound KRAS4b.
    McLean MA; Stephen AG; Sligar SG
    Biochemistry; 2019 Aug; 58(33):3537-3545. PubMed ID: 31339036
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Active and Inactive Cdc42 Differ in Their Insert Region Conformational Dynamics.
    Haspel N; Jang H; Nussinov R
    Biophys J; 2021 Jan; 120(2):306-318. PubMed ID: 33347888
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Reconstitution and characterization of BRAF in complex with 14-3-3 and KRAS4B on nanodiscs.
    Liu NF; Enomoto M; Marshall CB; Ikura M
    Protein Sci; 2024 Jun; 33(6):e5016. PubMed ID: 38747381
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Exploring CRD mobility during RAS/RAF engagement at the membrane.
    Nguyen K; López CA; Neale C; Van QN; Carpenter TS; Di Natale F; Travers T; Tran TH; Chan AH; Bhatia H; Frank PH; Tonelli M; Zhang X; Gulten G; Reddy T; Burns V; Oppelstrup T; Hengartner N; Simanshu DK; Bremer PT; Chen D; Glosli JN; Shrestha R; Turbyville T; Streitz FH; Nissley DV; Ingólfsson HI; Stephen AG; Lightstone FC; Gnanakaran S
    Biophys J; 2022 Oct; 121(19):3630-3650. PubMed ID: 35778842
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The quaternary assembly of KRas4B with Raf-1 at the membrane.
    Jang H; Zhang M; Nussinov R
    Comput Struct Biotechnol J; 2020; 18():737-748. PubMed ID: 32257057
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Arl2-Mediated Allosteric Release of Farnesylated KRas4B from Shuttling Factor PDEδ.
    Ozdemir ES; Jang H; Gursoy A; Keskin O; Nussinov R
    J Phys Chem B; 2018 Aug; 122(30):7503-7513. PubMed ID: 29961325
    [TBL] [Abstract][Full Text] [Related]  

  • 9.
    Lu H; Hu Z; Faraudo J; Martí J
    Nanoscale; 2023 Dec; 15(47):19359-19368. PubMed ID: 38014474
    [TBL] [Abstract][Full Text] [Related]  

  • 10. KRas4B-PDE6δ complex stabilization by small molecules obtained by virtual screening affects Ras signaling in pancreatic cancer.
    Casique-Aguirre D; Briseño-Díaz P; García-Gutiérrez P; la Rosa CHG; Quintero-Barceinas RS; Rojo-Domínguez A; Vergara I; Medina LA; Correa-Basurto J; Bello M; Hernández-Rivas R; Del RocioThompson-Bonilla M; Vargas M
    BMC Cancer; 2018 Dec; 18(1):1299. PubMed ID: 30594165
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Ras conformational switching: simulating nucleotide-dependent conformational transitions with accelerated molecular dynamics.
    Grant BJ; Gorfe AA; McCammon JA
    PLoS Comput Biol; 2009 Mar; 5(3):e1000325. PubMed ID: 19300489
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Deciphering the conformational transitions of LIMK2 active and inactive states to ponder specific druggable states through microsecond scale molecular dynamics simulation.
    Nagarajan H; Samdani A; Umashankar V; Jeyakanthan J
    J Comput Aided Mol Des; 2022 Jun; 36(6):459-482. PubMed ID: 35652973
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Coarse grained modelling highlights the binding differences in the two different allosteric sites of the Human Kinesin EG5 and its implications in inhibitor design.
    Alexandar SP; Yennamalli RM; Ulaganathan V
    Comput Biol Chem; 2022 Aug; 99():107708. PubMed ID: 35717732
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structural basis of recognition of farnesylated and methylated KRAS4b by PDEδ.
    Dharmaiah S; Bindu L; Tran TH; Gillette WK; Frank PH; Ghirlando R; Nissley DV; Esposito D; McCormick F; Stephen AG; Simanshu DK
    Proc Natl Acad Sci U S A; 2016 Nov; 113(44):E6766-E6775. PubMed ID: 27791178
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Molecular mechanism of the association and dissociation of Deltarasin from the heterodimeric KRas4B-PDEδ complex.
    Bello M; Correa-Basurto J; Vargas-Mejía MÁ
    Biopolymers; 2019 Nov; 110(11):e23333. PubMed ID: 31568570
    [TBL] [Abstract][Full Text] [Related]  

  • 16. How Anionic Lipids Affect Spatiotemporal Properties of KRAS4B on Model Membranes.
    Ngo VA; Sarkar S; Neale C; Garcia AE
    J Phys Chem B; 2020 Jul; 124(26):5434-5453. PubMed ID: 32438809
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Monitoring Ras Interactions with the Nucleotide Exchange Factor Son of Sevenless (Sos) Using Site-specific NMR Reporter Signals and Intrinsic Fluorescence.
    Vo U; Vajpai N; Flavell L; Bobby R; Breeze AL; Embrey KJ; Golovanov AP
    J Biol Chem; 2016 Jan; 291(4):1703-1718. PubMed ID: 26565026
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Nucleotide-Specific Autoinhibition of Full-Length K-Ras4B Identified by Extensive Conformational Sampling.
    Dudas B; Merzel F; Jang H; Nussinov R; Perahia D; Balog E
    Front Mol Biosci; 2020; 7():145. PubMed ID: 32754617
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Studying early structural changes in SOS1 mediated KRAS activation mechanism.
    Bhadhadhara K; Jani V; Koulgi S; Sonavane U; Joshi R
    Curr Res Struct Biol; 2024; 7():100115. PubMed ID: 38188543
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mechanistic insights into the effect of phosphorylation on Ras conformational dynamics and its interactions with cell signaling proteins.
    Wang Y; Ji D; Lei C; Chen Y; Qiu Y; Li X; Li M; Ni D; Pu J; Zhang J; Fu Q; Liu Y; Lu S
    Comput Struct Biotechnol J; 2021; 19():1184-1199. PubMed ID: 33680360
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.