BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

170 related articles for article (PubMed ID: 33985415)

  • 1. Autophagy is critical for cysteine metabolism in pancreatic cancer through regulation of SLC7A11.
    Mukhopadhyay S; Kimmelman AC
    Autophagy; 2021 Jun; 17(6):1561-1562. PubMed ID: 33985415
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Autophagy is required for proper cysteine homeostasis in pancreatic cancer through regulation of SLC7A11.
    Mukhopadhyay S; Biancur DE; Parker SJ; Yamamoto K; Banh RS; Paulo JA; Mancias JD; Kimmelman AC
    Proc Natl Acad Sci U S A; 2021 Feb; 118(6):. PubMed ID: 33531365
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Targeting autophagy as a therapeutic strategy against pancreatic cancer.
    Yamamoto K; Iwadate D; Kato H; Nakai Y; Tateishi K; Fujishiro M
    J Gastroenterol; 2022 Sep; 57(9):603-618. PubMed ID: 35727403
    [TBL] [Abstract][Full Text] [Related]  

  • 4. UBL4A inhibits autophagy-mediated proliferation and metastasis of pancreatic ductal adenocarcinoma via targeting LAMP1.
    Chen H; Li L; Hu J; Zhao Z; Ji L; Cheng C; Zhang G; Zhang T; Li Y; Chen H; Pan S; Sun B
    J Exp Clin Cancer Res; 2019 Jul; 38(1):297. PubMed ID: 31288830
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I.
    Yamamoto K; Venida A; Yano J; Biancur DE; Kakiuchi M; Gupta S; Sohn ASW; Mukhopadhyay S; Lin EY; Parker SJ; Banh RS; Paulo JA; Wen KW; Debnath J; Kim GE; Mancias JD; Fearon DT; Perera RM; Kimmelman AC
    Nature; 2020 May; 581(7806):100-105. PubMed ID: 32376951
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cysteine depletion induces pancreatic tumor ferroptosis in mice.
    Badgley MA; Kremer DM; Maurer HC; DelGiorno KE; Lee HJ; Purohit V; Sagalovskiy IR; Ma A; Kapilian J; Firl CEM; Decker AR; Sastra SA; Palermo CF; Andrade LR; Sajjakulnukit P; Zhang L; Tolstyka ZP; Hirschhorn T; Lamb C; Liu T; Gu W; Seeley ES; Stone E; Georgiou G; Manor U; Iuga A; Wahl GM; Stockwell BR; Lyssiotis CA; Olive KP
    Science; 2020 Apr; 368(6486):85-89. PubMed ID: 32241947
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Roles of autophagy and metabolism in pancreatic cancer cell adaptation to environmental challenges.
    Maertin S; Elperin JM; Lotshaw E; Sendler M; Speakman SD; Takakura K; Reicher BM; Mareninova OA; Grippo PJ; Mayerle J; Lerch MM; Gukovskaya AS
    Am J Physiol Gastrointest Liver Physiol; 2017 Nov; 313(5):G524-G536. PubMed ID: 28705806
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Autophagy supports mitochondrial metabolism through the regulation of iron homeostasis in pancreatic cancer.
    Mukhopadhyay S; Encarnación-Rosado J; Lin EY; Sohn ASW; Zhang H; Mancias JD; Kimmelman AC
    Sci Adv; 2023 Apr; 9(16):eadf9284. PubMed ID: 37075122
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mitochondrial Calcium Uniporter Drives Metastasis and Confers a Targetable Cystine Dependency in Pancreatic Cancer.
    Wang X; Li Y; Li Z; Lin S; Wang H; Sun J; Lan C; Wu L; Sun D; Huang C; Singh PK; Hempel N; Trebak M; DeNicola GM; Hao J; Yang S
    Cancer Res; 2022 Jun; 82(12):2254-2268. PubMed ID: 35413105
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Autophagy Contributes to Metabolic Reprogramming and Therapeutic Resistance in Pancreatic Tumors.
    Reyes-Castellanos G; Abdel Hadi N; Carrier A
    Cells; 2022 Jan; 11(3):. PubMed ID: 35159234
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Selective autophagy of MHC-I promotes immune evasion of pancreatic cancer.
    Yamamoto K; Venida A; Perera RM; Kimmelman AC
    Autophagy; 2020 Aug; 16(8):1524-1525. PubMed ID: 32459143
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Autophagy fuels mitochondrial function through regulation of iron metabolism in pancreatic cancer.
    Mukhopadhyay S; Encarnacion-Rosado J; Kimmelman AC
    Autophagy; 2024 Apr; 20(4):963-964. PubMed ID: 37312426
    [TBL] [Abstract][Full Text] [Related]  

  • 13. UDP-glucose dehydrogenase supports autophagy-deficient PDAC growth via increasing hyaluronic acid biosynthesis.
    Fan M; Huo S; Guo Y; Wang R; Hao W; Zhang Z; Wang L; Zhao Y
    Cell Rep; 2024 Feb; 43(2):113808. PubMed ID: 38367236
    [TBL] [Abstract][Full Text] [Related]  

  • 14. TGFB1-induced autophagy affects the pattern of pancreatic cancer progression in distinct ways depending on SMAD4 status.
    Liang C; Xu J; Meng Q; Zhang B; Liu J; Hua J; Zhang Y; Shi S; Yu X
    Autophagy; 2020 Mar; 16(3):486-500. PubMed ID: 31177911
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Enhanced mitochondrial glutamine anaplerosis suppresses pancreatic cancer growth through autophagy inhibition.
    Jeong SM; Hwang S; Park K; Yang S; Seong RH
    Sci Rep; 2016 Aug; 6():30767. PubMed ID: 27477484
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Lysosome inhibition sensitizes pancreatic cancer to replication stress by aspartate depletion.
    Elliott IA; Dann AM; Xu S; Kim SS; Abt ER; Kim W; Poddar S; Moore A; Zhou L; Williams JL; Capri JR; Ghukasyan R; Matsumura C; Tucker DA; Armstrong WR; Cabebe AE; Wu N; Li L; Le TM; Radu CG; Donahue TR
    Proc Natl Acad Sci U S A; 2019 Apr; 116(14):6842-6847. PubMed ID: 30894490
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Transcriptional control of autophagy-lysosome function drives pancreatic cancer metabolism.
    Perera RM; Stoykova S; Nicolay BN; Ross KN; Fitamant J; Boukhali M; Lengrand J; Deshpande V; Selig MK; Ferrone CR; Settleman J; Stephanopoulos G; Dyson NJ; Zoncu R; Ramaswamy S; Haas W; Bardeesy N
    Nature; 2015 Aug; 524(7565):361-5. PubMed ID: 26168401
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Myoferlin controls mitochondrial structure and activity in pancreatic ductal adenocarcinoma, and affects tumor aggressiveness.
    Rademaker G; Hennequière V; Brohée L; Nokin MJ; Lovinfosse P; Durieux F; Gofflot S; Bellier J; Costanza B; Herfs M; Peiffer R; Bettendorff L; Deroanne C; Thiry M; Delvenne P; Hustinx R; Bellahcène A; Castronovo V; Peulen O
    Oncogene; 2018 Aug; 37(32):4398-4412. PubMed ID: 29720728
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Blockage of SLC31A1-dependent copper absorption increases pancreatic cancer cell autophagy to resist cell death.
    Yu Z; Zhou R; Zhao Y; Pan Y; Liang H; Zhang JS; Tai S; Jin L; Teng CB
    Cell Prolif; 2019 Mar; 52(2):e12568. PubMed ID: 30706544
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cystine transporter regulation of pentose phosphate pathway dependency and disulfide stress exposes a targetable metabolic vulnerability in cancer.
    Liu X; Olszewski K; Zhang Y; Lim EW; Shi J; Zhang X; Zhang J; Lee H; Koppula P; Lei G; Zhuang L; You MJ; Fang B; Li W; Metallo CM; Poyurovsky MV; Gan B
    Nat Cell Biol; 2020 Apr; 22(4):476-486. PubMed ID: 32231310
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.