156 related articles for article (PubMed ID: 33990405)
1. Molecular Determinants Underlying Delta Selective Compound 2 Activity at
Falk-Petersen CB; Rostrup F; Löffler R; Buchleithner S; Harpsøe K; Gloriam DE; Frølund B; Wellendorph P
Mol Pharmacol; 2021 Jul; 100(1):46-56. PubMed ID: 33990405
[TBL] [Abstract][Full Text] [Related]
2. Structural Determinants for the Mode of Action of Imidazopyridine DS2 at δ-Containing γ-Aminobutyric Acid Type A Receptors.
Rostrup F; Falk-Petersen CB; Harpso E K; Buchleithner S; Conforti I; Jung S; Gloriam DE; Schirmeister T; Wellendorph P; Fro Lund B
J Med Chem; 2021 Apr; 64(8):4730-4743. PubMed ID: 33847501
[TBL] [Abstract][Full Text] [Related]
3. A study of subunit selectivity, mechanism and site of action of the delta selective compound 2 (DS2) at human recombinant and rodent native GABA(A) receptors.
Jensen ML; Wafford KA; Brown AR; Belelli D; Lambert JJ; Mirza NR
Br J Pharmacol; 2013 Mar; 168(5):1118-32. PubMed ID: 23061935
[TBL] [Abstract][Full Text] [Related]
4. Novel compounds selectively enhance delta subunit containing GABA A receptors and increase tonic currents in thalamus.
Wafford KA; van Niel MB; Ma QP; Horridge E; Herd MB; Peden DR; Belelli D; Lambert JJ
Neuropharmacology; 2009 Jan; 56(1):182-9. PubMed ID: 18762200
[TBL] [Abstract][Full Text] [Related]
5. The contribution of δ subunit-containing GABAA receptors to phasic and tonic conductance changes in cerebellum, thalamus and neocortex.
Ye Z; McGee TP; Houston CM; Brickley SG
Front Neural Circuits; 2013; 7():203. PubMed ID: 24391550
[TBL] [Abstract][Full Text] [Related]
6. Etomidate produces similar allosteric modulation in α1β3δ and α1β3γ2L GABA(A) receptors.
Feng HJ; Jounaidi Y; Haburcak M; Yang X; Forman SA
Br J Pharmacol; 2014 Feb; 171(3):789-98. PubMed ID: 24199598
[TBL] [Abstract][Full Text] [Related]
7. Positive modulation of synaptic and extrasynaptic GABAA receptors by an antagonist of the high affinity benzodiazepine binding site.
Middendorp SJ; Maldifassi MC; Baur R; Sigel E
Neuropharmacology; 2015 Aug; 95():459-67. PubMed ID: 25963418
[TBL] [Abstract][Full Text] [Related]
8. A pharmacological characterization of GABA, THIP and DS2 at binary α4β3 and β3δ receptors: GABA activates β3δ receptors via the β3(+)δ(-) interface.
Lee HJ; Absalom NL; Hanrahan JR; van Nieuwenhuijzen P; Ahring PK; Chebib M
Brain Res; 2016 Aug; 1644():222-30. PubMed ID: 27181518
[TBL] [Abstract][Full Text] [Related]
9. Toward Understanding Functional Properties and Subunit Arrangement of α4β2δ γ-Aminobutyric Acid, Type A (GABAA) Receptors.
Wongsamitkul N; Baur R; Sigel E
J Biol Chem; 2016 Aug; 291(35):18474-83. PubMed ID: 27382064
[TBL] [Abstract][Full Text] [Related]
10. The dual modulatory effects of efavirenz on GABA
Huang R; Chen Z; Dolan S; Schetz JA; Dillon GH
Neuropharmacology; 2017 Jul; 121():167-178. PubMed ID: 28456686
[TBL] [Abstract][Full Text] [Related]
11. Identifying Drugs that Bind Selectively to Intersubunit General Anesthetic Sites in the
Jayakar SS; Zhou X; Chiara DC; Jarava-Barrera C; Savechenkov PY; Bruzik KS; Tortosa M; Miller KW; Cohen JB
Mol Pharmacol; 2019 Jun; 95(6):615-628. PubMed ID: 30952799
[TBL] [Abstract][Full Text] [Related]
12. Specificity of intersubunit general anesthetic-binding sites in the transmembrane domain of the human α1β3γ2 γ-aminobutyric acid type A (GABAA) receptor.
Chiara DC; Jayakar SS; Zhou X; Zhang X; Savechenkov PY; Bruzik KS; Miller KW; Cohen JB
J Biol Chem; 2013 Jul; 288(27):19343-57. PubMed ID: 23677991
[TBL] [Abstract][Full Text] [Related]
13. Covalent modification of GABAA receptor isoforms by a diazepam analogue provides evidence for a novel benzodiazepine binding site that prevents modulation by these drugs.
Baur R; Tan KR; Lüscher BP; Gonthier A; Goeldner M; Sigel E
J Neurochem; 2008 Sep; 106(6):2353-63. PubMed ID: 18643789
[TBL] [Abstract][Full Text] [Related]
14. A single glycine residue at the entrance to the first membrane-spanning domain of the gamma-aminobutyric acid type A receptor beta(2) subunit affects allosteric sensitivity to GABA and anesthetics.
Carlson BX; Engblom AC; Kristiansen U; Schousboe A; Olsen RW
Mol Pharmacol; 2000 Mar; 57(3):474-84. PubMed ID: 10692487
[TBL] [Abstract][Full Text] [Related]
15. A potent photoreactive general anesthetic with novel binding site selectivity for GABA
Shalabi AR; Yu Z; Zhou X; Jounaidi Y; Chen H; Dai J; Kent DE; Feng HJ; Forman SA; Cohen JB; Bruzik KS; Miller KW
Eur J Med Chem; 2020 May; 194():112261. PubMed ID: 32247113
[TBL] [Abstract][Full Text] [Related]
16. Probing the molecular basis for affinity/potency- and efficacy-based subtype-selectivity exhibited by benzodiazepine-site modulators at GABA
Söderhielm PC; Balle T; Bak-Nyhus S; Zhang M; Hansen KM; Ahring PK; Jensen AA
Biochem Pharmacol; 2018 Dec; 158():339-358. PubMed ID: 30121248
[TBL] [Abstract][Full Text] [Related]
17. A Benzodiazepine Ligand with Improved GABA
Simeone X; Koniuszewski F; Müllegger M; Smetka A; Steudle F; Puthenkalam R; Ernst M; Scholze P
Mol Pharmacol; 2021 Jan; 99(1):39-48. PubMed ID: 33268553
[TBL] [Abstract][Full Text] [Related]
18. Bicuculline and gabazine are allosteric inhibitors of channel opening of the GABAA receptor.
Ueno S; Bracamontes J; Zorumski C; Weiss DS; Steinbach JH
J Neurosci; 1997 Jan; 17(2):625-34. PubMed ID: 8987785
[TBL] [Abstract][Full Text] [Related]
19. Mutagenesis and computational docking studies support the existence of a histamine binding site at the extracellular β3+β3- interface of homooligomeric β3 GABAA receptors.
Hoerbelt P; Ramerstorfer J; Ernst M; Sieghart W; Thomson JL; Hough LB; Fleck MW
Neuropharmacology; 2016 Sep; 108():252-63. PubMed ID: 27140694
[TBL] [Abstract][Full Text] [Related]
20. Selective modulation of different GABAA receptor isoforms by diazepam and etomidate in hippocampal neurons.
Seymour VA; Curmi JP; Howitt SM; Casarotto MG; Laver DR; Tierney ML
Int J Biochem Cell Biol; 2012 Sep; 44(9):1491-500. PubMed ID: 22704937
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]