BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

373 related articles for article (PubMed ID: 33992806)

  • 1. Rationally designed DNA therapeutics can modulate human TH expression by controlling specific GQ formation in its promoter.
    Beals N; Farhath MM; Kharel P; Croos B; Mahendran T; Johnson J; Basu S
    Mol Ther; 2022 Feb; 30(2):831-844. PubMed ID: 33992806
    [TBL] [Abstract][Full Text] [Related]  

  • 2. G-Quadruplex-Enabling Sequence within the Human Tyrosine Hydroxylase Promoter Differentially Regulates Transcription.
    Farhath MM; Thompson M; Ray S; Sewell A; Balci H; Basu S
    Biochemistry; 2015 Sep; 54(36):5533-45. PubMed ID: 26284527
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Tyrosine hydroxylase (TH), its cofactor tetrahydrobiopterin (BH4), other catecholamine-related enzymes, and their human genes in relation to the drug and gene therapies of Parkinson's disease (PD): historical overview and future prospects.
    Nagatsu T; Nagatsu I
    J Neural Transm (Vienna); 2016 Nov; 123(11):1255-1278. PubMed ID: 27491309
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Overview of tyrosine hydroxylase in Parkinson's disease.
    Zhu Y; Zhang J; Zeng Y
    CNS Neurol Disord Drug Targets; 2012 Jun; 11(4):350-8. PubMed ID: 22483316
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Current status of tyrosine hydroxylase in management of Parkinson's disease.
    Feve AP
    CNS Neurol Disord Drug Targets; 2012 Jun; 11(4):450-5. PubMed ID: 22583428
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Human tyrosine hydroxylase in Parkinson's disease and in related disorders.
    Nagatsu T; Nakashima A; Ichinose H; Kobayashi K
    J Neural Transm (Vienna); 2019 Apr; 126(4):397-409. PubMed ID: 29995172
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Triple transduction with adeno-associated virus vectors expressing tyrosine hydroxylase, aromatic-L-amino-acid decarboxylase, and GTP cyclohydrolase I for gene therapy of Parkinson's disease.
    Shen Y; Muramatsu SI; Ikeguchi K; Fujimoto KI; Fan DS; Ogawa M; Mizukami H; Urabe M; Kume A; Nagatsu I; Urano F; Suzuki T; Ichinose H; Nagatsu T; Monahan J; Nakano I; Ozawa K
    Hum Gene Ther; 2000 Jul; 11(11):1509-19. PubMed ID: 10945765
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The role of tyrosine hydroxylase-dopamine pathway in Parkinson's disease pathogenesis.
    Zhou ZD; Saw WT; Ho PGH; Zhang ZW; Zeng L; Chang YY; Sun AXY; Ma DR; Wang HY; Zhou L; Lim KL; Tan EK
    Cell Mol Life Sci; 2022 Nov; 79(12):599. PubMed ID: 36409355
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Role of N-terminus of tyrosine hydroxylase in the biosynthesis of catecholamines.
    Nakashima A; Hayashi N; Kaneko YS; Mori K; Sabban EL; Nagatsu T; Ota A
    J Neural Transm (Vienna); 2009 Nov; 116(11):1355-62. PubMed ID: 19396395
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Identification and characterization of potential cis-regulatory elements governing transcriptional activation of the rat tyrosine hydroxylase gene.
    Yang C; Kim HS; Seo H; Kim KS
    J Neurochem; 1998 Oct; 71(4):1358-68. PubMed ID: 9751166
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Effect of siRNA-induced silencing of cellular prion protein on tyrosine hydroxylase expression in the substantia nigra of a rat model of Parkinson's disease.
    Wang X; Yang HA; Wang XN; Du YF
    Genet Mol Res; 2016 May; 15(2):. PubMed ID: 27173342
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The function of tyrosine hydroxylase in the normal and Parkinsonian brain.
    Tolleson C; Claassen D
    CNS Neurol Disord Drug Targets; 2012 Jun; 11(4):381-6. PubMed ID: 22483314
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Enhanced tyrosine hydroxylase activity induces oxidative stress, causes accumulation of autotoxic catecholamine metabolites, and augments amphetamine effects in vivo.
    Vecchio LM; Sullivan P; Dunn AR; Bermejo MK; Fu R; Masoud ST; Gregersen E; Urs NM; Nazari R; Jensen PH; Ramsey A; Goldstein DS; Miller GW; Salahpour A
    J Neurochem; 2021 Aug; 158(4):960-979. PubMed ID: 33991113
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Coexpression of tyrosine hydroxylase, GTP cyclohydrolase I, aromatic amino acid decarboxylase, and vesicular monoamine transporter 2 from a helper virus-free herpes simplex virus type 1 vector supports high-level, long-term biochemical and behavioral correction of a rat model of Parkinson's disease.
    Sun M; Kong L; Wang X; Holmes C; Gao Q; Zhang GR; Pfeilschifter J; Goldstein DS; Geller AI
    Hum Gene Ther; 2004 Dec; 15(12):1177-96. PubMed ID: 15684695
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cloning and cell type-specific regulation of the human tyrosine hydroxylase gene promoter.
    Kim TE; Park MJ; Choi EJ; Lee HS; Lee SH; Yoon SH; Oh CK; Lee BJ; Kim SU; Lee YS; Lee MA
    Biochem Biophys Res Commun; 2003 Dec; 312(4):1123-31. PubMed ID: 14651989
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Development of an enzyme-linked immunosorbent assay (ELISA) to measure the level of tyrosine hydroxylase protein in brain tissue from Parkinson's disease models.
    Fauss D; Motter R; Dofiles L; Rodrigues MA; You M; Diep L; Yang Y; Seto P; Tanaka K; Baker J; Bergeron M
    J Neurosci Methods; 2013 May; 215(2):245-57. PubMed ID: 23537934
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Alpha-synuclein aggregation alters tyrosine hydroxylase phosphorylation and immunoreactivity: lessons from viral transduction of knockout mice.
    Alerte TN; Akinfolarin AA; Friedrich EE; Mader SA; Hong CS; Perez RG
    Neurosci Lett; 2008 Apr; 435(1):24-9. PubMed ID: 18314273
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Differential modification of dopamine transporter and tyrosine hydroxylase mRNAs in midbrain of subjects with Parkinson's, Alzheimer's with parkinsonism, and Alzheimer's disease.
    Joyce JN; Smutzer G; Whitty CJ; Myers A; Bannon MJ
    Mov Disord; 1997 Nov; 12(6):885-97. PubMed ID: 9399211
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Tyrosine hydroxylase protein and messenger RNA in the dopaminergic nigral neurons of patients with Parkinson's disease.
    Kastner A; Hirsch EC; Agid Y; Javoy-Agid F
    Brain Res; 1993 Mar; 606(2):341-5. PubMed ID: 8098254
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Encounters between Cas9/dCas9 and G-Quadruplexes: Implications for Transcription Regulation and Cas9-Mediated DNA Cleavage.
    Hoque ME; Mustafa G; Basu S; Balci H
    ACS Synth Biol; 2021 May; 10(5):972-978. PubMed ID: 33970608
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.