304 related articles for article (PubMed ID: 33996822)
1. The Absence of PTEN in Breast Cancer Is a Driver of MLN4924 Resistance.
Du MG; Peng ZQ; Gai WB; Liu F; Liu W; Chen YJ; Li HC; Zhang X; Liu CH; Zhang LQ; Jiang H; Xie P
Front Cell Dev Biol; 2021; 9():667435. PubMed ID: 33996822
[No Abstract] [Full Text] [Related]
2. Inhibition of NEDD8 NEDDylation induced apoptosis in acute myeloid leukemia cells via p53 signaling pathway.
Chen Y; Sun L
Biosci Rep; 2022 Aug; 42(8):. PubMed ID: 35880551
[TBL] [Abstract][Full Text] [Related]
3. MLN4924 (Pevonedistat), a protein neddylation inhibitor, suppresses proliferation and migration of human clear cell renal cell carcinoma.
Tong S; Si Y; Yu H; Zhang L; Xie P; Jiang W
Sci Rep; 2017 Jul; 7(1):5599. PubMed ID: 28717191
[TBL] [Abstract][Full Text] [Related]
4. Validation of NEDD8-conjugating enzyme UBC12 as a new therapeutic target in lung cancer.
Li L; Kang J; Zhang W; Cai L; Wang S; Liang Y; Jiang Y; Liu X; Zhang Y; Ruan H; Chen G; Wang M; Jia L
EBioMedicine; 2019 Jul; 45():81-91. PubMed ID: 31208947
[TBL] [Abstract][Full Text] [Related]
5. Suppression of glioblastoma by targeting the overactivated protein neddylation pathway.
Hua W; Li C; Yang Z; Li L; Jiang Y; Yu G; Zhu W; Liu Z; Duan S; Chu Y; Yang M; Zhang Y; Mao Y; Jia L
Neuro Oncol; 2015 Oct; 17(10):1333-43. PubMed ID: 25904638
[TBL] [Abstract][Full Text] [Related]
6. The Protein Neddylation Inhibitor MLN4924 Suppresses Patient-Derived Glioblastoma Cells via Inhibition of ERK and AKT Signaling.
Han S; Shin H; Oh JW; Oh YJ; Her NG; Nam DH
Cancers (Basel); 2019 Nov; 11(12):. PubMed ID: 31771104
[TBL] [Abstract][Full Text] [Related]
7. A first-in-class inhibitor, MLN4924 (pevonedistat), induces cell-cycle arrest, senescence, and apoptosis in human renal cell carcinoma by suppressing UBE2M-dependent neddylation modification.
Xu B; Deng Y; Bi R; Guo H; Shu C; Shah NK; Chang J; Liu G; Du Y; Wei W; Wang C
Cancer Chemother Pharmacol; 2018 Jun; 81(6):1083-1093. PubMed ID: 29667067
[TBL] [Abstract][Full Text] [Related]
8. The NEDD8-activating enzyme E1 UBA3 orchestrates the immunosuppressive microenvironment in lung adenocarcinoma via the NF-кB pathway.
Lin X; Yang S; Zhou C; Ao C; Sun D
Med Oncol; 2023 Sep; 40(10):286. PubMed ID: 37656220
[TBL] [Abstract][Full Text] [Related]
9. The Nedd8-activating enzyme inhibitor MLN4924 (TAK-924/Pevonedistat) induces apoptosis via c-Myc-Noxa axis in head and neck squamous cell carcinoma.
Zhang W; Liang Y; Li L; Wang X; Yan Z; Dong C; Zeng MS; Zhong Q; Liu XK; Yu J; Sun S; Liu X; Kang J; Zhao H; Jeong LS; Zhang Y; Jia L
Cell Prolif; 2019 Mar; 52(2):e12536. PubMed ID: 30341788
[TBL] [Abstract][Full Text] [Related]
10. PTEN loss drives resistance to the neddylation inhibitor MLN4924 in glioblastoma and can be overcome with TOP2A inhibitors.
Ferdosi SR; Taylor B; Lee M; Tang N; Peng S; Bybee R; Reid G; Hartman L; Garcia-Mansfield K; Sharma R; Pirrotte P; Ma J; Parisian AD; Furnari F; Dhruv HD; Berens ME
Neuro Oncol; 2022 Nov; 24(11):1857-1868. PubMed ID: 35305088
[TBL] [Abstract][Full Text] [Related]
11. NEDD8-mediated neddylation is required for human endometrial stromal proliferation and decidualization.
Liao Y; Jiang Y; He H; Ni H; Tu Z; Zhang S; Wang B; Lou J; Quan S; Wang H
Hum Reprod; 2015 Jul; 30(7):1665-76. PubMed ID: 26003431
[TBL] [Abstract][Full Text] [Related]
12. Targeting protein neddylation with an NEDD8-activating enzyme inhibitor MLN4924 induced apoptosis or senescence in human lymphoma cells.
Wang Y; Luo Z; Pan Y; Wang W; Zhou X; Jeong LS; Chu Y; Liu J; Jia L
Cancer Biol Ther; 2015; 16(3):420-9. PubMed ID: 25782162
[TBL] [Abstract][Full Text] [Related]
13. An overactive neddylation pathway serves as a therapeutic target and MLN4924 enhances the anticancer activity of cisplatin in pancreatic cancer.
Zeng Y; Iv YS; Pan QH; Zhou YG; Li H
Oncol Lett; 2019 Sep; 18(3):2724-2732. PubMed ID: 31404297
[TBL] [Abstract][Full Text] [Related]
14. Activation of the β‑TrCP/IκBα/inflammation axis limits the sensitivity of liver cancer cells to neddylation inhibition.
Xiong H; Zheng D; Liu Y; Ma L; Meng L; Yang Z; Yang Z
Oncol Rep; 2022 Nov; 48(5):. PubMed ID: 36169173
[TBL] [Abstract][Full Text] [Related]
15. Inhibitory effect of a neddylation blockade on HTLV-1-infected T cells
Ishikawa C; Mori N
Leuk Lymphoma; 2024 Mar; ():1-11. PubMed ID: 38489672
[TBL] [Abstract][Full Text] [Related]
16. Neddylation-Independent Activities of MLN4924.
Mao H; Sun Y
Adv Exp Med Biol; 2020; 1217():363-372. PubMed ID: 31898238
[TBL] [Abstract][Full Text] [Related]
17. Neddylation inhibition upregulates PD-L1 expression and enhances the efficacy of immune checkpoint blockade in glioblastoma.
Zhou S; Zhao X; Yang Z; Yang R; Chen C; Zhao K; Wang W; Ma Y; Zhang Q; Wang X
Int J Cancer; 2019 Aug; 145(3):763-774. PubMed ID: 31044422
[TBL] [Abstract][Full Text] [Related]
18. The Nedd8-activating enzyme inhibitor MLN4924 suppresses colon cancer cell growth
Lv Y; Li B; Han K; Xiao Y; Yu X; Ma Y; Jiao Z; Gao J
Korean J Physiol Pharmacol; 2018 Nov; 22(6):617-625. PubMed ID: 30402022
[TBL] [Abstract][Full Text] [Related]
19. Overactivated neddylation pathway as a therapeutic target in lung cancer.
Li L; Wang M; Yu G; Chen P; Li H; Wei D; Zhu J; Xie L; Jia H; Shi J; Li C; Yao W; Wang Y; Gao Q; Jeong LS; Lee HW; Yu J; Hu F; Mei J; Wang P; Chu Y; Qi H; Yang M; Dong Z; Sun Y; Hoffman RM; Jia L
J Natl Cancer Inst; 2014 Jun; 106(6):dju083. PubMed ID: 24853380
[TBL] [Abstract][Full Text] [Related]
20. UBC12-mediated SREBP-1 neddylation worsens metastatic tumor prognosis.
Heo MJ; Kang SH; Kim YS; Lee JM; Yu J; Kim HR; Lim H; Kim KM; Jung J; Jeong LS; Moon A; Kim SG
Int J Cancer; 2020 Nov; 147(9):2550-2563. PubMed ID: 32449166
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]