BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

168 related articles for article (PubMed ID: 34013250)

  • 1. Modulation of lysosomal function as a therapeutic approach for coronaviral infections.
    Liu Y; Lear T; Larsen M; Lin B; Cao Q; Alfaras I; Kennerdell J; Salminen L; Camarco D; Lockwood K; Ma J; Liu J; Tan J; Myerburg M; Chen Y; St Croix C; Sekine Y; Evankovich J; Finkel T; Chen B
    Res Sq; 2021 Apr; ():. PubMed ID: 34013250
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The E3 ubiquitin ligase STUB1 regulates autophagy and mitochondrial biogenesis by modulating TFEB activity.
    Rao L; Sha Y; Eissa NT
    Mol Cell Oncol; 2017; 4(6):e1372867. PubMed ID: 29209655
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Coxsackievirus B3 targets TFEB to disrupt lysosomal function.
    Mohamud Y; Tang H; Xue YC; Liu H; Ng CS; Bahreyni A; Luo H
    Autophagy; 2021 Dec; 17(12):3924-3938. PubMed ID: 33691586
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Neuronal-Targeted TFEB Accelerates Lysosomal Degradation of APP, Reducing Aβ Generation and Amyloid Plaque Pathogenesis.
    Xiao Q; Yan P; Ma X; Liu H; Perez R; Zhu A; Gonzales E; Tripoli DL; Czerniewski L; Ballabio A; Cirrito JR; Diwan A; Lee JM
    J Neurosci; 2015 Sep; 35(35):12137-51. PubMed ID: 26338325
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Trehalose causes low-grade lysosomal stress to activate TFEB and the autophagy-lysosome biogenesis response.
    Jeong SJ; Stitham J; Evans TD; Zhang X; Rodriguez-Velez A; Yeh YS; Tao J; Takabatake K; Epelman S; Lodhi IJ; Schilling JD; DeBosch BJ; Diwan A; Razani B
    Autophagy; 2021 Nov; 17(11):3740-3752. PubMed ID: 33706671
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Impaired TFEB-mediated lysosomal biogenesis promotes the development of pancreatitis in mice and is associated with human pancreatitis.
    Wang S; Ni HM; Chao X; Wang H; Bridges B; Kumer S; Schmitt T; Mareninova O; Gukovskaya A; De Lisle RC; Ballabio A; Pacher P; Ding WX
    Autophagy; 2019 Nov; 15(11):1954-1969. PubMed ID: 30894069
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A stress response p38 MAP kinase inhibitor SB202190 promoted TFEB/TFE3-dependent autophagy and lysosomal biogenesis independent of p38.
    Yang C; Zhu Z; Tong BC; Iyaswamy A; Xie WJ; Zhu Y; Sreenivasmurthy SG; Senthilkumar K; Cheung KH; Song JX; Zhang HJ; Li M
    Redox Biol; 2020 May; 32():101445. PubMed ID: 32037305
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Importance of TFEB acetylation in control of its transcriptional activity and lysosomal function in response to histone deacetylase inhibitors.
    Zhang J; Wang J; Zhou Z; Park JE; Wang L; Wu S; Sun X; Lu L; Wang T; Lin Q; Sze SK; Huang D; Shen HM
    Autophagy; 2018; 14(6):1043-1059. PubMed ID: 30059277
    [TBL] [Abstract][Full Text] [Related]  

  • 9. STUB1 regulates TFEB-induced autophagy-lysosome pathway.
    Sha Y; Rao L; Settembre C; Ballabio A; Eissa NT
    EMBO J; 2017 Sep; 36(17):2544-2552. PubMed ID: 28754656
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Lysosome biogenesis in health and disease.
    Bajaj L; Lotfi P; Pal R; Ronza AD; Sharma J; Sardiello M
    J Neurochem; 2019 Mar; 148(5):573-589. PubMed ID: 30092616
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Multiparameter phenotypic screening for endogenous TFEB and TFE3 translocation identifies novel chemical series modulating lysosome function.
    Carling PJ; Ryan BJ; McGuinness W; Kataria S; Humble SW; Milde S; Duce JA; Kapadia N; Zuercher WJ; Davis JB; Di Daniel E; Wade-Martins R
    Autophagy; 2023 Feb; 19(2):692-705. PubMed ID: 35786165
    [TBL] [Abstract][Full Text] [Related]  

  • 12. p53 down-regulates SARS coronavirus replication and is targeted by the SARS-unique domain and PLpro via E3 ubiquitin ligase RCHY1.
    Ma-Lauer Y; Carbajo-Lozoya J; Hein MY; Müller MA; Deng W; Lei J; Meyer B; Kusov Y; von Brunn B; Bairad DR; Hünten S; Drosten C; Hermeking H; Leonhardt H; Mann M; Hilgenfeld R; von Brunn A
    Proc Natl Acad Sci U S A; 2016 Aug; 113(35):E5192-201. PubMed ID: 27519799
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The Calcineurin-TFEB-p62 Pathway Mediates the Activation of Cardiac Macroautophagy by Proteasomal Malfunction.
    Pan B; Li J; Parajuli N; Tian Z; Wu P; Lewno MT; Zou J; Wang W; Bedford L; Mayer RJ; Fang J; Liu J; Cui T; Su H; Wang X
    Circ Res; 2020 Jul; 127(4):502-518. PubMed ID: 32366200
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB.
    Settembre C; Zoncu R; Medina DL; Vetrini F; Erdin S; Erdin S; Huynh T; Ferron M; Karsenty G; Vellard MC; Facchinetti V; Sabatini DM; Ballabio A
    EMBO J; 2012 Mar; 31(5):1095-108. PubMed ID: 22343943
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Deacetylation of TFEB promotes fibrillar Aβ degradation by upregulating lysosomal biogenesis in microglia.
    Bao J; Zheng L; Zhang Q; Li X; Zhang X; Li Z; Bai X; Zhang Z; Huo W; Zhao X; Shang S; Wang Q; Zhang C; Ji J
    Protein Cell; 2016 Jun; 7(6):417-33. PubMed ID: 27209302
    [TBL] [Abstract][Full Text] [Related]  

  • 16. TFEB and the CLEAR network.
    Settembre C; Medina DL
    Methods Cell Biol; 2015; 126():45-62. PubMed ID: 25665440
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Lysosomotropic drugs activate TFEB via lysosomal membrane fluidization and consequent inhibition of mTORC1 activity.
    Zhitomirsky B; Yunaev A; Kreiserman R; Kaplan A; Stark M; Assaraf YG
    Cell Death Dis; 2018 Dec; 9(12):1191. PubMed ID: 30546014
    [TBL] [Abstract][Full Text] [Related]  

  • 18. TFEB Dependent Autophagy-Lysosomal Pathway: An Emerging Pharmacological Target in Sepsis.
    Liu X; Zheng X; Lu Y; Chen Q; Zheng J; Zhou H
    Front Pharmacol; 2021; 12():794298. PubMed ID: 34899355
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Overactivation of hepatic mechanistic target of rapamycin kinase complex 1 (mTORC1) is associated with low transcriptional activity of transcription factor EB and lysosomal dysfunction in dairy cows with clinical ketosis.
    Fang Z; Li X; Wang S; Jiang Q; Loor JJ; Jiang X; Ju L; Yu H; Shen T; Chen M; Song Y; Wang Z; Du X; Liu G
    J Dairy Sci; 2022 May; 105(5):4520-4533. PubMed ID: 35248377
    [TBL] [Abstract][Full Text] [Related]  

  • 20. MPB, a novel berberine derivative, enhances lysosomal and bactericidal properties via TGF-β-activated kinase 1-dependent activation of the transcription factor EB.
    Liu X; Zhang N; Liu Y; Liu L; Zeng Q; Yin M; Wang Y; Song D; Deng H
    FASEB J; 2019 Jan; 33(1):1468-1481. PubMed ID: 30161000
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.