BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

189 related articles for article (PubMed ID: 34017832)

  • 1. Ceramide-Induced Lysosomal Biogenesis and Exocytosis in Early-Onset Preeclampsia Promotes Exosomal Release of SMPD1 Causing Endothelial Dysfunction.
    Ermini L; Farrell A; Alahari S; Ausman J; Park C; Sallais J; Melland-Smith M; Porter T; Edson M; Nevo O; Litvack M; Post M; Caniggia I
    Front Cell Dev Biol; 2021; 9():652651. PubMed ID: 34017832
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Disruption of sphingolipid metabolism augments ceramide-induced autophagy in preeclampsia.
    Melland-Smith M; Ermini L; Chauvin S; Craig-Barnes H; Tagliaferro A; Todros T; Post M; Caniggia I
    Autophagy; 2015 Apr; 11(4):653-69. PubMed ID: 25853898
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Evidence for lysosomal biogenesis proteome defect and impaired autophagy in preeclampsia.
    Nakashima A; Cheng SB; Ikawa M; Yoshimori T; Huber WJ; Menon R; Huang Z; Fierce J; Padbury JF; Sadovsky Y; Saito S; Sharma S
    Autophagy; 2020 Oct; 16(10):1771-1785. PubMed ID: 31856641
    [TBL] [Abstract][Full Text] [Related]  

  • 4. TFEB activation promotes the recruitment of lysosomal glycohydrolases β-hexosaminidase and β-galactosidase to the plasma membrane.
    Magini A; Polchi A; Urbanelli L; Cesselli D; Beltrami A; Tancini B; Emiliani C
    Biochem Biophys Res Commun; 2013 Oct; 440(2):251-7. PubMed ID: 24055709
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Lysosomotropic drugs activate TFEB via lysosomal membrane fluidization and consequent inhibition of mTORC1 activity.
    Zhitomirsky B; Yunaev A; Kreiserman R; Kaplan A; Stark M; Assaraf YG
    Cell Death Dis; 2018 Dec; 9(12):1191. PubMed ID: 30546014
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Medial calcification in the arterial wall of smooth muscle cell-specific Smpd1 transgenic mice: A ceramide-mediated vasculopathy.
    Bhat OM; Yuan X; Cain C; Salloum FN; Li PL
    J Cell Mol Med; 2020 Jan; 24(1):539-553. PubMed ID: 31743567
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibition of acid sphingomyelinase disrupts LYNUS signaling and triggers autophagy.
    Justice MJ; Bronova I; Schweitzer KS; Poirier C; Blum JS; Berdyshev EV; Petrache I
    J Lipid Res; 2018 Apr; 59(4):596-606. PubMed ID: 29378782
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Early secretory pathway-resident Zn transporter proteins contribute to cellular sphingolipid metabolism through activation of sphingomyelin phosphodiesterase 1.
    Ueda S; Manabe Y; Kubo N; Morino N; Yuasa H; Shiotsu M; Tsuji T; Sugawara T; Kambe T
    Am J Physiol Cell Physiol; 2022 May; 322(5):C948-C959. PubMed ID: 35294847
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Trophoblast debris extruded from preeclamptic placentae activates endothelial cells: a mechanism by which the placenta communicates with the maternal endothelium.
    Shen F; Wei J; Snowise S; DeSousa J; Stone P; Viall C; Chen Q; Chamley L
    Placenta; 2014 Oct; 35(10):839-47. PubMed ID: 25096950
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Adjustment of Dysregulated Ceramide Metabolism in a Murine Model of Sepsis-Induced Cardiac Dysfunction.
    Chung HY; Kollmey AS; Schrepper A; Kohl M; Bläss MF; Stehr SN; Lupp A; Gräler MH; Claus RA
    Int J Mol Sci; 2017 Apr; 18(4):. PubMed ID: 28420138
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Clomiphene citrate induces nuclear translocation of the TFEB transcription factor and triggers apoptosis by enhancing lysosomal membrane permeabilization.
    Li W; Lin J; Shi Z; Wen J; Li Y; Liu Z; Diao A
    Biochem Pharmacol; 2019 Apr; 162():191-201. PubMed ID: 30471247
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Impaired TFEB-Mediated Lysosome Biogenesis and Autophagy Promote Chronic Ethanol-Induced Liver Injury and Steatosis in Mice.
    Chao X; Wang S; Zhao K; Li Y; Williams JA; Li T; Chavan H; Krishnamurthy P; He XC; Li L; Ballabio A; Ni HM; Ding WX
    Gastroenterology; 2018 Sep; 155(3):865-879.e12. PubMed ID: 29782848
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Acid Sphingomyelinase Inhibition Stabilizes Hepatic Ceramide Content and Improves Hepatic Biotransformation Capacity in a Murine Model of Polymicrobial Sepsis.
    Chung HY; Witt CJ; Hurtado-Oliveros J; Wickel J; Gräler MH; Lupp A; Claus RA
    Int J Mol Sci; 2018 Oct; 19(10):. PubMed ID: 30326559
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Acid Sphingomyelinase Promotes Endothelial Stress Response in Systemic Inflammation and Sepsis.
    Chung HY; Hupe DC; Otto GP; Sprenger M; Bunck AC; Dorer MJ; Bockmeyer CL; Deigner HP; Gräler MH; Claus RA
    Mol Med; 2016 Sep; 22():412-423. PubMed ID: 27341515
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Ceramide-induced BOK promotes mitochondrial fission in preeclampsia.
    Ausman J; Abbade J; Ermini L; Farrell A; Tagliaferro A; Post M; Caniggia I
    Cell Death Dis; 2018 Feb; 9(3):298. PubMed ID: 29463805
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Augmented trophoblast cell death in preeclampsia can proceed via ceramide-mediated necroptosis.
    Bailey LJ; Alahari S; Tagliaferro A; Post M; Caniggia I
    Cell Death Dis; 2017 Feb; 8(2):e2590. PubMed ID: 28151467
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Acid sphingomyelinase regulates platelet cell membrane scrambling, secretion, and thrombus formation.
    Münzer P; Borst O; Walker B; Schmid E; Feijge MA; Cosemans JM; Chatterjee M; Schmidt EM; Schmidt S; Towhid ST; Leibrock C; Elvers M; Schaller M; Seizer P; Ferlinz K; May AE; Gulbins E; Heemskerk JW; Gawaz M; Lang F
    Arterioscler Thromb Vasc Biol; 2014 Jan; 34(1):61-71. PubMed ID: 24233488
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Sub-lethal oxidative stress induces lysosome biogenesis via a lysosomal membrane permeabilization-cathepsin-caspase 3-transcription factor EB-dependent pathway.
    Leow SM; Chua SX; Venkatachalam G; Shen L; Luo L; Clement MV
    Oncotarget; 2017 Mar; 8(10):16170-16189. PubMed ID: 28002813
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Critical Role of TFEB-Mediated Lysosomal Biogenesis in Alcohol-Induced Pancreatitis in Mice and Humans.
    Wang S; Ni HM; Chao X; Ma X; Kolodecik T; De Lisle R; Ballabio A; Pacher P; Ding WX
    Cell Mol Gastroenterol Hepatol; 2020; 10(1):59-81. PubMed ID: 31987928
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Trehalose induces autophagy via lysosomal-mediated TFEB activation in models of motoneuron degeneration.
    Rusmini P; Cortese K; Crippa V; Cristofani R; Cicardi ME; Ferrari V; Vezzoli G; Tedesco B; Meroni M; Messi E; Piccolella M; Galbiati M; Garrè M; Morelli E; Vaccari T; Poletti A
    Autophagy; 2019 Apr; 15(4):631-651. PubMed ID: 30335591
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.