These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

103 related articles for article (PubMed ID: 34019908)

  • 1. Novel small molecule inhibitor of Kpnβ1 induces cell cycle arrest and apoptosis in cancer cells.
    Ajayi-Smith A; van der Watt P; Mkwanazi N; Carden S; Trent JO; Leaner VD
    Exp Cell Res; 2021 Jul; 404(2):112637. PubMed ID: 34019908
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibition of Kpnβ1 mediated nuclear import enhances cisplatin chemosensitivity in cervical cancer.
    Chi RA; van der Watt P; Wei W; Birrer MJ; Leaner VD
    BMC Cancer; 2021 Feb; 21(1):106. PubMed ID: 33530952
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Targeting the Nuclear Import Receptor Kpnβ1 as an Anticancer Therapeutic.
    van der Watt PJ; Chi A; Stelma T; Stowell C; Strydom E; Carden S; Angus L; Hadley K; Lang D; Wei W; Birrer MJ; Trent JO; Leaner VD
    Mol Cancer Ther; 2016 Apr; 15(4):560-73. PubMed ID: 26832790
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A tight balance of Karyopherin β1 expression is required in cervical cancer cells.
    Carden S; van der Watt P; Chi A; Ajayi-Smith A; Hadley K; Leaner VD
    BMC Cancer; 2018 Nov; 18(1):1123. PubMed ID: 30445944
    [TBL] [Abstract][Full Text] [Related]  

  • 5. KPNB1-mediated nuclear import is required for motility and inflammatory transcription factor activity in cervical cancer cells.
    Stelma T; Leaner VD
    Oncotarget; 2017 May; 8(20):32833-32847. PubMed ID: 28427184
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inhibition of the nuclear transporter, Kpnβ1, results in prolonged mitotic arrest and activation of the intrinsic apoptotic pathway in cervical cancer cells.
    Angus L; van der Watt PJ; Leaner VD
    Carcinogenesis; 2014 May; 35(5):1121-31. PubMed ID: 24398670
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The Karyopherin proteins, Crm1 and Karyopherin beta1, are overexpressed in cervical cancer and are critical for cancer cell survival and proliferation.
    van der Watt PJ; Maske CP; Hendricks DT; Parker MI; Denny L; Govender D; Birrer MJ; Leaner VD
    Int J Cancer; 2009 Apr; 124(8):1829-40. PubMed ID: 19117056
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Upregulation of KPNβ1 in gastric cancer cell promotes tumor cell proliferation and predicts poor prognosis.
    Zhu J; Wang Y; Huang H; Yang Q; Cai J; Wang Q; Gu X; Xu P; Zhang S; Li M; Ding H; Yang L
    Tumour Biol; 2016 Jan; 37(1):661-72. PubMed ID: 26242264
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Suppression of Kpnβ1 expression inhibits human breast cancer cell proliferation by abrogating nuclear transport of Her2.
    Sheng C; Qiu J; He Z; Wang H; Wang Q; Guo Z; Zhu L; Ni Q
    Oncol Rep; 2018 Feb; 39(2):554-564. PubMed ID: 29251332
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Overexpression of Kpnβ1 and Kpnα2 importin proteins in cancer derives from deregulated E2F activity.
    van der Watt PJ; Ngarande E; Leaner VD
    PLoS One; 2011; 6(11):e27723. PubMed ID: 22125623
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Upregulation of nuclear transporter, Kpnβ1, contributes to accelerated cell proliferation- and cell adhesion-mediated drug resistance (CAM-DR) in diffuse large B-cell lymphoma.
    He S; Miao X; Wu Y; Zhu X; Miao X; Yin H; He Y; Li C; Liu Y; Lu X; Chen Y; Wang Y; Xu X
    J Cancer Res Clin Oncol; 2016 Mar; 142(3):561-72. PubMed ID: 26498772
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Suppression of the nuclear transporter-KPNβ1 expression inhibits tumor proliferation in hepatocellular carcinoma.
    Yang L; Hu B; Zhang Y; Qiang S; Cai J; Huang W; Gong C; Zhang T; Zhang S; Xu P; Wu X; Liu J
    Med Oncol; 2015 Apr; 32(4):128. PubMed ID: 25794490
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The nuclear import receptor Kpnβ1 and its potential as an anticancer therapeutic target.
    van der Watt PJ; Stowell CL; Leaner VD
    Crit Rev Eukaryot Gene Expr; 2013; 23(1):1-10. PubMed ID: 23557333
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Importin β1 mediates nuclear factor-κB signal transduction into the nuclei of myeloma cells and affects their proliferation and apoptosis.
    Yan W; Li R; He J; Du J; Hou J
    Cell Signal; 2015 Apr; 27(4):851-9. PubMed ID: 25643631
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A mass spectrometry-based approach for the identification of Kpnβ1 binding partners in cancer cells.
    Okpara MO; Hermann C; van der Watt PJ; Garnett S; Blackburn JM; Leaner VD
    Sci Rep; 2022 Nov; 12(1):20171. PubMed ID: 36418423
    [TBL] [Abstract][Full Text] [Related]  

  • 16. High Kpnβ1 expression promotes non-small cell lung cancer proliferation and chemoresistance via the PI3-kinase/AKT pathway.
    Wang H; Wang D; Li C; Zhang X; Zhou X; Huang J
    Tissue Cell; 2018 Apr; 51():39-48. PubMed ID: 29622086
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Nuclear import of exogenous FGF1 requires the ER-protein LRRC59 and the importins Kpnα1 and Kpnβ1.
    Zhen Y; Sørensen V; Skjerpen CS; Haugsten EM; Jin Y; Wälchli S; Olsnes S; Wiedlocha A
    Traffic; 2012 May; 13(5):650-64. PubMed ID: 22321063
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Apatinib, a novel tyrosine kinase inhibitor, suppresses tumor growth in cervical cancer and synergizes with Paclitaxel.
    Qiu H; Li J; Liu Q; Tang M; Wang Y
    Cell Cycle; 2018; 17(10):1235-1244. PubMed ID: 29886786
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inhibition of Karyopherin beta 1 suppresses prostate cancer growth.
    Yang J; Guo Y; Lu C; Zhang R; Wang Y; Luo L; Zhang Y; Chu CH; Wang KJ; Obbad S; Yan W; Li X
    Oncogene; 2019 Jun; 38(24):4700-4714. PubMed ID: 30742095
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Zoledronic acid inhibits the growth of cancer stem cell derived from cervical cancer cell by attenuating their stemness phenotype and inducing apoptosis and cell cycle arrest through the Erk1/2 and Akt pathways.
    Wang L; Liu Y; Zhou Y; Wang J; Tu L; Sun Z; Wang X; Luo F
    J Exp Clin Cancer Res; 2019 Feb; 38(1):93. PubMed ID: 30791957
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.