311 related articles for article (PubMed ID: 34021132)
1. Cytoplasmic FUS triggers early behavioral alterations linked to cortical neuronal hyperactivity and inhibitory synaptic defects.
Scekic-Zahirovic J; Sanjuan-Ruiz I; Kan V; Megat S; De Rossi P; Dieterlé S; Cassel R; Jamet M; Kessler P; Wiesner D; Tzeplaeff L; Demais V; Sahadevan S; Hembach KM; Muller HP; Picchiarelli G; Mishra N; Antonucci S; Dirrig-Grosch S; Kassubek J; Rasche V; Ludolph A; Boutillier AL; Roselli F; Polymenidou M; Lagier-Tourenne C; Liebscher S; Dupuis L
Nat Commun; 2021 May; 12(1):3028. PubMed ID: 34021132
[TBL] [Abstract][Full Text] [Related]
2. RNA-binding ability of FUS regulates neurodegeneration, cytoplasmic mislocalization and incorporation into stress granules associated with FUS carrying ALS-linked mutations.
Daigle JG; Lanson NA; Smith RB; Casci I; Maltare A; Monaghan J; Nichols CD; Kryndushkin D; Shewmaker F; Pandey UB
Hum Mol Genet; 2013 Mar; 22(6):1193-205. PubMed ID: 23257289
[TBL] [Abstract][Full Text] [Related]
3. Widespread FUS mislocalization is a molecular hallmark of amyotrophic lateral sclerosis.
Tyzack GE; Luisier R; Taha DM; Neeves J; Modic M; Mitchell JS; Meyer I; Greensmith L; Newcombe J; Ule J; Luscombe NM; Patani R
Brain; 2019 Sep; 142(9):2572-2580. PubMed ID: 31368485
[TBL] [Abstract][Full Text] [Related]
4. Neuronal dysfunction caused by FUSR521G promotes ALS-associated phenotypes that are attenuated by NF-κB inhibition.
Pelaez MC; Desmeules A; Gelon PA; Glasson B; Marcadet L; Rodgers A; Phaneuf D; Pozzi S; Dutchak PA; Julien JP; Sephton CF
Acta Neuropathol Commun; 2023 Nov; 11(1):182. PubMed ID: 37974279
[TBL] [Abstract][Full Text] [Related]
5. FUS causes synaptic hyperexcitability in Drosophila dendritic arborization neurons.
Machamer JB; Woolums BM; Fuller GG; Lloyd TE
Brain Res; 2018 Aug; 1693(Pt A):55-66. PubMed ID: 29625118
[TBL] [Abstract][Full Text] [Related]
6. ALS-associated mutations in FUS disrupt the axonal distribution and function of SMN.
Groen EJ; Fumoto K; Blokhuis AM; Engelen-Lee J; Zhou Y; van den Heuvel DM; Koppers M; van Diggelen F; van Heest J; Demmers JA; Kirby J; Shaw PJ; Aronica E; Spliet WG; Veldink JH; van den Berg LH; Pasterkamp RJ
Hum Mol Genet; 2013 Sep; 22(18):3690-704. PubMed ID: 23681068
[TBL] [Abstract][Full Text] [Related]
7. Motor neuron intrinsic and extrinsic mechanisms contribute to the pathogenesis of FUS-associated amyotrophic lateral sclerosis.
Scekic-Zahirovic J; Oussini HE; Mersmann S; Drenner K; Wagner M; Sun Y; Allmeroth K; Dieterlé S; Sinniger J; Dirrig-Grosch S; René F; Dormann D; Haass C; Ludolph AC; Lagier-Tourenne C; Storkebaum E; Dupuis L
Acta Neuropathol; 2017 Jun; 133(6):887-906. PubMed ID: 28243725
[TBL] [Abstract][Full Text] [Related]
8. Synaptic FUS accumulation triggers early misregulation of synaptic RNAs in a mouse model of ALS.
Sahadevan S; Hembach KM; Tantardini E; Pérez-Berlanga M; Hruska-Plochan M; Megat S; Weber J; Schwarz P; Dupuis L; Robinson MD; De Rossi P; Polymenidou M
Nat Commun; 2021 May; 12(1):3027. PubMed ID: 34021139
[TBL] [Abstract][Full Text] [Related]
9. Directly converted patient-specific induced neurons mirror the neuropathology of FUS with disrupted nuclear localization in amyotrophic lateral sclerosis.
Lim SM; Choi WJ; Oh KW; Xue Y; Choi JY; Kim SH; Nahm M; Kim YE; Lee J; Noh MY; Lee S; Hwang S; Ki CS; Fu XD; Kim SH
Mol Neurodegener; 2016 Jan; 11():8. PubMed ID: 26795035
[TBL] [Abstract][Full Text] [Related]
10. Humanized mutant FUS drives progressive motor neuron degeneration without aggregation in 'FUSDelta14' knockin mice.
Devoy A; Kalmar B; Stewart M; Park H; Burke B; Noy SJ; Redhead Y; Humphrey J; Lo K; Jaeger J; Mejia Maza A; Sivakumar P; Bertolin C; Soraru G; Plagnol V; Greensmith L; Acevedo Arozena A; Isaacs AM; Davies B; Fratta P; Fisher EMC
Brain; 2017 Nov; 140(11):2797-2805. PubMed ID: 29053787
[TBL] [Abstract][Full Text] [Related]
11. ALS-associated mutation FUS-R521C causes DNA damage and RNA splicing defects.
Qiu H; Lee S; Shang Y; Wang WY; Au KF; Kamiya S; Barmada SJ; Finkbeiner S; Lui H; Carlton CE; Tang AA; Oldham MC; Wang H; Shorter J; Filiano AJ; Roberson ED; Tourtellotte WG; Chen B; Tsai LH; Huang EJ
J Clin Invest; 2014 Mar; 124(3):981-99. PubMed ID: 24509083
[TBL] [Abstract][Full Text] [Related]
12. Defects in synapse structure and function precede motor neuron degeneration in Drosophila models of FUS-related ALS.
Shahidullah M; Le Marchand SJ; Fei H; Zhang J; Pandey UB; Dalva MB; Pasinelli P; Levitan IB
J Neurosci; 2013 Dec; 33(50):19590-8. PubMed ID: 24336723
[TBL] [Abstract][Full Text] [Related]
13. Arginine methylation by PRMT1 regulates nuclear-cytoplasmic localization and toxicity of FUS/TLS harbouring ALS-linked mutations.
Tradewell ML; Yu Z; Tibshirani M; Boulanger MC; Durham HD; Richard S
Hum Mol Genet; 2012 Jan; 21(1):136-49. PubMed ID: 21965298
[TBL] [Abstract][Full Text] [Related]
14. Pur-alpha regulates cytoplasmic stress granule dynamics and ameliorates FUS toxicity.
Daigle JG; Krishnamurthy K; Ramesh N; Casci I; Monaghan J; McAvoy K; Godfrey EW; Daniel DC; Johnson EM; Monahan Z; Shewmaker F; Pasinelli P; Pandey UB
Acta Neuropathol; 2016 Apr; 131(4):605-20. PubMed ID: 26728149
[TBL] [Abstract][Full Text] [Related]
15. Toxic gain of function from mutant FUS protein is crucial to trigger cell autonomous motor neuron loss.
Scekic-Zahirovic J; Sendscheid O; El Oussini H; Jambeau M; Sun Y; Mersmann S; Wagner M; Dieterlé S; Sinniger J; Dirrig-Grosch S; Drenner K; Birling MC; Qiu J; Zhou Y; Li H; Fu XD; Rouaux C; Shelkovnikova T; Witting A; Ludolph AC; Kiefer F; Storkebaum E; Lagier-Tourenne C; Dupuis L
EMBO J; 2016 May; 35(10):1077-97. PubMed ID: 26951610
[TBL] [Abstract][Full Text] [Related]
16. Inactivation of Hippo and cJun-N-terminal Kinase (JNK) signaling mitigate FUS mediated neurodegeneration in vivo.
Gogia N; Sarkar A; Mehta AS; Ramesh N; Deshpande P; Kango-Singh M; Pandey UB; Singh A
Neurobiol Dis; 2020 Jul; 140():104837. PubMed ID: 32199908
[TBL] [Abstract][Full Text] [Related]
17. Comparative interactomics analysis of different ALS-associated proteins identifies converging molecular pathways.
Blokhuis AM; Koppers M; Groen EJN; van den Heuvel DMA; Dini Modigliani S; Anink JJ; Fumoto K; van Diggelen F; Snelting A; Sodaar P; Verheijen BM; Demmers JAA; Veldink JH; Aronica E; Bozzoni I; den Hertog J; van den Berg LH; Pasterkamp RJ
Acta Neuropathol; 2016 Aug; 132(2):175-196. PubMed ID: 27164932
[TBL] [Abstract][Full Text] [Related]
18. Overexpression of an ALS-associated FUS mutation in
Markert SM; Skoruppa M; Yu B; Mulcahy B; Zhen M; Gao S; Sendtner M; Stigloher C
Biol Open; 2020 Dec; 9(12):. PubMed ID: 33148607
[TBL] [Abstract][Full Text] [Related]
19. ALS mutations of FUS suppress protein translation and disrupt the regulation of nonsense-mediated decay.
Kamelgarn M; Chen J; Kuang L; Jin H; Kasarskis EJ; Zhu H
Proc Natl Acad Sci U S A; 2018 Dec; 115(51):E11904-E11913. PubMed ID: 30455313
[TBL] [Abstract][Full Text] [Related]
20. In vivo stress granule misprocessing evidenced in a FUS knock-in ALS mouse model.
Zhang X; Wang F; Hu Y; Chen R; Meng D; Guo L; Lv H; Guan J; Jia Y
Brain; 2020 May; 143(5):1350-1367. PubMed ID: 32358598
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
