BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

287 related articles for article (PubMed ID: 34021134)

  • 1. Qki activates Srebp2-mediated cholesterol biosynthesis for maintenance of eye lens transparency.
    Shin S; Zhou H; He C; Wei Y; Wang Y; Shingu T; Zeng A; Wang S; Zhou X; Li H; Zhang Q; Mo Q; Long J; Lan F; Chen Y; Hu J
    Nat Commun; 2021 May; 12(1):3005. PubMed ID: 34021134
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Qki regulates myelinogenesis through Srebp2-dependent cholesterol biosynthesis.
    Zhou X; Shin S; He C; Zhang Q; Rasband MN; Ren J; Dai C; Zorrilla-Veloz RI; Shingu T; Yuan L; Wang Y; Chen Y; Lan F; Hu J
    Elife; 2021 May; 10():. PubMed ID: 33942715
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Ring finger protein 5 activates sterol regulatory element-binding protein 2 (SREBP2) to promote cholesterol biosynthesis via inducing polyubiquitination of SREBP chaperone SCAP.
    Kuan YC; Takahashi Y; Maruyama T; Shimizu M; Yamauchi Y; Sato R
    J Biol Chem; 2020 Mar; 295(12):3918-3928. PubMed ID: 32054686
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Downregulation of cholesterol biosynthesis genes in the forebrain of ERCC1-deficient mice.
    Smith SC; Robinson AR; Niedernhofer LJ; Hetman M
    Neurobiol Dis; 2012 Mar; 45(3):1136-44. PubMed ID: 22245387
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cholesterol biosynthesis supports the growth of hepatocarcinoma lesions depleted of fatty acid synthase in mice and humans.
    Che L; Chi W; Qiao Y; Zhang J; Song X; Liu Y; Li L; Jia J; Pilo MG; Wang J; Cigliano A; Ma Z; Kuang W; Tang Z; Zhang Z; Shui G; Ribback S; Dombrowski F; Evert M; Pascale RM; Cossu C; Pes GM; Osborne TF; Calvisi DF; Chen X; Chen L
    Gut; 2020 Jan; 69(1):177-186. PubMed ID: 30954949
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A spontaneous mutation in Srebf2 leads to cataracts and persistent skin wounds in the lens opacity 13 (lop13) mouse.
    Merath KM; Chang B; Dubielzig R; Jeannotte R; Sidjanin DJ
    Mamm Genome; 2011 Dec; 22(11-12):661-73. PubMed ID: 21858719
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Loss of Quaking RNA binding protein disrupts the expression of genes associated with astrocyte maturation in mouse brain.
    Sakers K; Liu Y; Llaci L; Lee SM; Vasek MJ; Rieger MA; Brophy S; Tycksen E; Lewis R; Maloney SE; Dougherty JD
    Nat Commun; 2021 Mar; 12(1):1537. PubMed ID: 33750804
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Quaking, an RNA-binding protein, is a critical regulator of vascular smooth muscle cell phenotype.
    van der Veer EP; de Bruin RG; Kraaijeveld AO; de Vries MR; Bot I; Pera T; Segers FM; Trompet S; van Gils JM; Roeten MK; Beckers CM; van Santbrink PJ; Janssen A; van Solingen C; Swildens J; de Boer HC; Peters EA; Bijkerk R; Rousch M; Doop M; Kuiper J; Schalij MJ; van der Wal AC; Richard S; van Berkel TJ; Pickering JG; Hiemstra PS; Goumans MJ; Rabelink TJ; de Vries AA; Quax PH; Jukema JW; Biessen EA; van Zonneveld AJ
    Circ Res; 2013 Oct; 113(9):1065-75. PubMed ID: 23963726
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Organ-specific cholesterol metabolic aberration fuels liver metastasis of colorectal cancer.
    Zhang KL; Zhu WW; Wang SH; Gao C; Pan JJ; Du ZG; Lu L; Jia HL; Dong QZ; Chen JH; Lu M; Qin LX
    Theranostics; 2021; 11(13):6560-6572. PubMed ID: 33995676
    [No Abstract]   [Full Text] [Related]  

  • 10. MMAB promotes negative feedback control of cholesterol homeostasis.
    Goedeke L; Canfrán-Duque A; Rotllan N; Chaube B; Thompson BM; Lee RG; Cline GW; McDonald JG; Shulman GI; Lasunción MA; Suárez Y; Fernández-Hernando C
    Nat Commun; 2021 Nov; 12(1):6448. PubMed ID: 34750386
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Dietary palm oil enhances Sterol regulatory element-binding protein 2-mediated cholesterol biosynthesis through inducing endoplasmic reticulum stress in muscle of large yellow croaker (
    Zhao Z; Li B; Chen Q; Xiang X; Xu X; Han S; Lai W; Li Y; Xu W; Mai K; Ai Q
    Br J Nutr; 2024 Feb; 131(4):553-566. PubMed ID: 37699661
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Sterol-responsive element-binding protein (SREBP) 2 down-regulates ATP-binding cassette transporter A1 in vascular endothelial cells: a novel role of SREBP in regulating cholesterol metabolism.
    Zeng L; Liao H; Liu Y; Lee TS; Zhu M; Wang X; Stemerman MB; Zhu Y; Shyy JY
    J Biol Chem; 2004 Nov; 279(47):48801-7. PubMed ID: 15358760
    [TBL] [Abstract][Full Text] [Related]  

  • 13. ABCA7 expression is regulated by cellular cholesterol through the SREBP2 pathway and associated with phagocytosis.
    Iwamoto N; Abe-Dohmae S; Sato R; Yokoyama S
    J Lipid Res; 2006 Sep; 47(9):1915-27. PubMed ID: 16788211
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Muscle stem cell polarity requires QKI-mediated alternative splicing of Integrin Alpha-7 (Itga7).
    Dominici C; Richard S
    Life Sci Alliance; 2022 May; 5(5):. PubMed ID: 35165120
    [TBL] [Abstract][Full Text] [Related]  

  • 15. SREBP2 Activation Induces Hepatic Long-chain Acyl-CoA Synthetase 1 (ACSL1) Expression in Vivo and in Vitro through a Sterol Regulatory Element (SRE) Motif of the ACSL1 C-promoter.
    Singh AB; Kan CF; Dong B; Liu J
    J Biol Chem; 2016 Mar; 291(10):5373-84. PubMed ID: 26728456
    [TBL] [Abstract][Full Text] [Related]  

  • 16. DnaJA4 is a SREBP-regulated chaperone involved in the cholesterol biosynthesis pathway.
    Robichon C; Varret M; Le Liepvre X; Lasnier F; Hajduch E; Ferré P; Dugail I
    Biochim Biophys Acta; 2006 Sep; 1761(9):1107-13. PubMed ID: 16950652
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Prion-induced activation of cholesterogenic gene expression by Srebp2 in neuronal cells.
    Bach C; Gilch S; Rost R; Greenwood AD; Horsch M; Hajj GN; Brodesser S; Facius A; Schädler S; Sandhoff K; Beckers J; Leib-Mösch C; Schätzl HM; Vorberg I
    J Biol Chem; 2009 Nov; 284(45):31260-9. PubMed ID: 19748890
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Sterol regulatory element-binding protein 2 maintains glioblastoma stem cells by keeping the balance between cholesterol biosynthesis and uptake.
    Gu D; Zhou F; You H; Gao J; Kang T; Dixit D; Wu Q; Yang K; Ci S; Shan D; Fan X; Yuan W; Zhang Q; Lu C; Li D; Zhao N; Shi Z; Gao W; Lin F; Man J; Wang Q; Qian X; Mack SC; Tao W; Agnihotri S; Zhang N; You Y; Rich JN; Zhang J; Wang X
    Neuro Oncol; 2023 Sep; 25(9):1578-1591. PubMed ID: 36934350
    [TBL] [Abstract][Full Text] [Related]  

  • 19. FoxO4 interacts with the sterol regulatory factor SREBP2 and the hypoxia inducible factor HIF2α at the CYP51 promoter.
    Zhu J; Jiang X; Chehab FF
    J Lipid Res; 2014 Mar; 55(3):431-42. PubMed ID: 24353279
    [TBL] [Abstract][Full Text] [Related]  

  • 20. GPHR-mediated acidification of the Golgi lumen is essential for cholesterol biosynthesis in the brain.
    Sou YS; Yamaguchi J; Kameda H; Masuda K; Maeda Y; Uchiyama Y; Koike M
    FEBS Lett; 2022 Nov; 596(22):2873-2888. PubMed ID: 36056653
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.