BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

137 related articles for article (PubMed ID: 34021971)

  • 1. Novel imidazo[2,1-b]thiazole-based anticancer agents as potential focal adhesion kinase inhibitors: Synthesis, in silico and in vitro evaluation.
    Başoğlu F; Ulusoy-Güzeldemirci N; Akalın-Çiftçi G; Çetinkaya S; Ece A
    Chem Biol Drug Des; 2021 Aug; 98(2):270-282. PubMed ID: 34021971
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Anticancer profile of newly synthesized BRAF inhibitors possess 5-(pyrimidin-4-yl)imidazo[2,1-b]thiazole scaffold.
    Abdel-Maksoud MS; Ammar UM; Oh CH
    Bioorg Med Chem; 2019 May; 27(10):2041-2051. PubMed ID: 30955995
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structural optimization of imidazothiazole derivatives affords a new promising series as B-Raf V600E inhibitors; synthesis, in vitro assay and in silico screening.
    Ammar UM; Abdel-Maksoud MS; Ali EMH; Mersal KI; Ho Yoo K; Oh CH
    Bioorg Chem; 2020 Jul; 100():103967. PubMed ID: 32470760
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Design, synthesis, and evaluation of novel imidazo[1,2-a][1,3,5]triazines and their derivatives as focal adhesion kinase inhibitors with antitumor activity.
    Dao P; Smith N; Tomkiewicz-Raulet C; Yen-Pon E; Camacho-Artacho M; Lietha D; Herbeuval JP; Coumoul X; Garbay C; Chen H
    J Med Chem; 2015 Jan; 58(1):237-51. PubMed ID: 25180654
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis, biological evaluation, and molecular docking studies of novel 2-styryl-5-nitroimidazole derivatives containing 1,4-benzodioxan moiety as FAK inhibitors with anticancer activity.
    Duan YT; Yao YF; Huang W; Makawana JA; Teraiya SB; Thumar NJ; Tang DJ; Tao XX; Wang ZC; Jiang AQ; Zhu HL
    Bioorg Med Chem; 2014 Jun; 22(11):2947-54. PubMed ID: 24792811
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Evaluation of imidazo[2,1-b]thiazole-based anticancer agents in one decade (2011-2020): Current status and future prospects.
    Sbenati RM; Semreen MH; Semreen AM; Shehata MK; Alsaghir FM; El-Gamal MI
    Bioorg Med Chem; 2021 Jan; 29():115897. PubMed ID: 33316752
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Design, synthesis and biological evaluation of 2,3-dihydroimidazo[2,1-b]thiazoles as dual EGFR and IGF1R inhibitors.
    Gadekar PK; Urunkar G; Roychowdhury A; Sharma R; Bose J; Khanna S; Damre A; Sarveswari S
    Bioorg Chem; 2021 Oct; 115():105151. PubMed ID: 34333424
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis, in vitro anticancer evaluation and in silico studies of novel imidazo[2,1-b]thiazole derivatives bearing pyrazole moieties.
    Ali AR; El-Bendary ER; Ghaly MA; Shehata IA
    Eur J Med Chem; 2014 Mar; 75():492-500. PubMed ID: 24576591
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Discovery of 7H-pyrrolo[2,3-d]pyridine derivatives as potent FAK inhibitors: Design, synthesis, biological evaluation and molecular docking study.
    Wang R; Zhao X; Yu S; Chen Y; Cui H; Wu T; Hao C; Zhao D; Cheng M
    Bioorg Chem; 2020 Sep; 102():104092. PubMed ID: 32707280
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis, biological evaluation, and molecular docking studies of novel 1,3,4-oxadiazole derivatives possessing benzotriazole moiety as FAK inhibitors with anticancer activity.
    Zhang S; Luo Y; He LQ; Liu ZJ; Jiang AQ; Yang YH; Zhu HL
    Bioorg Med Chem; 2013 Jul; 21(13):3723-9. PubMed ID: 23673215
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Modification of imidazothiazole derivatives gives promising activity in B-Raf kinase enzyme inhibition; synthesis, in vitro studies and molecular docking.
    Ammar UM; Abdel-Maksoud MS; Mersal KI; Ali EMH; Yoo KH; Choi HS; Lee JK; Cha SY; Oh CH
    Bioorg Med Chem Lett; 2020 Oct; 30(20):127478. PubMed ID: 32781217
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Design, Synthesis, and Evaluation of a New Series of Thiazole-Based Anticancer Agents as Potent Akt Inhibitors.
    Altıntop MD; Sever B; Akalın Çiftçi G; Özdemir A
    Molecules; 2018 May; 23(6):. PubMed ID: 29857484
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Design, synthesis and biological evaluation of novel 7H-pyrrolo[2,3-d]pyrimidine derivatives as potential FAK inhibitors and anticancer agents.
    Wang R; Chen Y; Zhao X; Yu S; Yang B; Wu T; Guo J; Hao C; Zhao D; Cheng M
    Eur J Med Chem; 2019 Dec; 183():111716. PubMed ID: 31550660
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis of Benzo[d]imidazo[2,1-b]thiazole-Propenone Conjugates as Cytotoxic and Apoptotic Inducing Agents.
    Shaik SP; Reddy TS; Sunkari S; Rao AVS; Babu KS; Bhargava SK; Kamal A
    Anticancer Agents Med Chem; 2019; 19(3):347-355. PubMed ID: 30479221
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Discovery of New Imidazo[2,1-
    Abdel-Maksoud MS; El-Gamal MI; Lee BS; Gamal El-Din MM; Jeon HR; Kwon D; Ammar UM; Mersal KI; Ali EMH; Lee KT; Yoo KH; Han DK; Lee JK; Kim G; Choi HS; Kwon YJ; Lee KH; Oh CH
    J Med Chem; 2021 May; 64(10):6877-6901. PubMed ID: 33999621
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Design, synthesis, in vitro and in silico evaluation of a new series of oxadiazole-based anticancer agents as potential Akt and FAK inhibitors.
    Altıntop MD; Sever B; Akalın Çiftçi G; Turan-Zitouni G; Kaplancıklı ZA; Özdemir A
    Eur J Med Chem; 2018 Jul; 155():905-924. PubMed ID: 29966916
    [TBL] [Abstract][Full Text] [Related]  

  • 17. New imidazo[2,1-b]thiazole derivatives: synthesis, in vitro anticancer evaluation, and in silico studies.
    Park JH; El-Gamal MI; Lee YS; Oh CH
    Eur J Med Chem; 2011 Dec; 46(12):5769-77. PubMed ID: 22033063
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis, anticancer effect and molecular modeling of new thiazolylpyrazolyl coumarin derivatives targeting VEGFR-2 kinase and inducing cell cycle arrest and apoptosis.
    Mohamed TK; Batran RZ; Elseginy SA; Ali MM; Mahmoud AE
    Bioorg Chem; 2019 Apr; 85():253-273. PubMed ID: 30641320
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis of novel 1,2,4-triazine scaffold as FAK inhibitors with antitumor activity.
    Dao P; Lietha D; Etheve-Quelquejeu M; Garbay C; Chen H
    Bioorg Med Chem Lett; 2017 Apr; 27(8):1727-1730. PubMed ID: 28284808
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis, biological evaluation and molecular docking studies of novel 2-(1,3,4-oxadiazol-2-ylthio)-1-phenylethanone derivatives.
    Zhang LR; Liu ZJ; Zhang H; Sun J; Luo Y; Zhao TT; Gong HB; Zhu HL
    Bioorg Med Chem; 2012 Jun; 20(11):3615-21. PubMed ID: 22541051
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.