BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

204 related articles for article (PubMed ID: 34029087)

  • 1. Inhibition of the Oxygen-Sensing Asparaginyl Hydroxylase Factor Inhibiting Hypoxia-Inducible Factor: A Potential Hypoxia Response Modulating Strategy.
    Wu Y; Li Z; McDonough MA; Schofield CJ; Zhang X
    J Med Chem; 2021 Jun; 64(11):7189-7209. PubMed ID: 34029087
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Kinetic Investigations of the Role of Factor Inhibiting Hypoxia-inducible Factor (FIH) as an Oxygen Sensor.
    Tarhonskaya H; Hardy AP; Howe EA; Loik ND; Kramer HB; McCullagh JS; Schofield CJ; Flashman E
    J Biol Chem; 2015 Aug; 290(32):19726-42. PubMed ID: 26112411
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Protein Hydroxylation by Hypoxia-Inducible Factor (HIF) Hydroxylases: Unique or Ubiquitous?
    Strowitzki MJ; Cummins EP; Taylor CT
    Cells; 2019 Apr; 8(5):. PubMed ID: 31035491
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Ferritin heavy chain controls the HIF-driven hypoxic response by activating the asparaginyl hydroxylase FIH.
    Jin P; Kang J; Lee MK; Park JW
    Biochem Biophys Res Commun; 2018 May; 499(3):475-481. PubMed ID: 29580991
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Ankyrin Repeat Proteins of Orf Virus Influence the Cellular Hypoxia Response Pathway.
    Chen DY; Fabrizio JA; Wilkins SE; Dave KA; Gorman JJ; Gleadle JM; Fleming SB; Peet DJ; Mercer AA
    J Virol; 2017 Jan; 91(1):. PubMed ID: 27795413
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Oxygen-dependent hydroxylation by FIH regulates the TRPV3 ion channel.
    Karttunen S; Duffield M; Scrimgeour NR; Squires L; Lim WL; Dallas ML; Scragg JL; Chicher J; Dave KA; Whitelaw ML; Peers C; Gorman JJ; Gleadle JM; Rychkov GY; Peet DJ
    J Cell Sci; 2015 Jan; 128(2):225-31. PubMed ID: 25413349
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Deletion of the
    Cai X; Zhang D; Wang J; Liu X; Ouyang G; Xiao W
    J Biol Chem; 2018 Oct; 293(40):15370-15380. PubMed ID: 30126845
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Biochemistry of the hypoxia-inducible factor hydroxylases.
    Fiorini G; Schofield CJ
    Curr Opin Chem Biol; 2024 Apr; 79():102428. PubMed ID: 38330792
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Quantitative mass spectrometry reveals dynamics of factor-inhibiting hypoxia-inducible factor-catalyzed hydroxylation.
    Singleton RS; Trudgian DC; Fischer R; Kessler BM; Ratcliffe PJ; Cockman ME
    J Biol Chem; 2011 Sep; 286(39):33784-94. PubMed ID: 21808058
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Tuning the Transcriptional Response to Hypoxia by Inhibiting Hypoxia-inducible Factor (HIF) Prolyl and Asparaginyl Hydroxylases.
    Chan MC; Ilott NE; Schödel J; Sims D; Tumber A; Lippl K; Mole DR; Pugh CW; Ratcliffe PJ; Ponting CP; Schofield CJ
    J Biol Chem; 2016 Sep; 291(39):20661-73. PubMed ID: 27502280
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structure of factor-inhibiting hypoxia-inducible factor 1: An asparaginyl hydroxylase involved in the hypoxic response pathway.
    Dann CE; Bruick RK; Deisenhofer J
    Proc Natl Acad Sci U S A; 2002 Nov; 99(24):15351-6. PubMed ID: 12432100
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The conservation and functionality of the oxygen-sensing enzyme Factor Inhibiting HIF (FIH) in non-vertebrates.
    Hampton-Smith RJ; Davenport BA; Nagarajan Y; Peet DJ
    PLoS One; 2019; 14(4):e0216134. PubMed ID: 31034531
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Regulation of Transactivation at C-TAD Domain of HIF-1
    Rani S; Roy S; Singh M; Kaithwas G
    Oxid Med Cell Longev; 2022; 2022():2407223. PubMed ID: 35592530
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Factor inhibiting HIF can catalyze two asparaginyl hydroxylations in VNVN motifs of ankyrin fold proteins.
    Leissing TM; Hardy AP; Chan H; Wang Y; Tumber A; Chowdhury R; Feng T; Coleman ML; Cockman ME; Kramer HB; Berridge G; Fischer R; Kessler BM; Ratcliffe PJ; Lu X; Schofield CJ
    J Biol Chem; 2022 Jun; 298(6):102020. PubMed ID: 35537551
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Evolution of hypoxia and hypoxia-inducible factor asparaginyl hydroxylase regulation in chronic kidney disease.
    Faivre A; Dissard R; Kuo W; Verissimo T; Legouis D; Arnoux G; Heckenmeyer C; Fernandez M; Tihy M; Rajaram RD; Delitsikou V; Le NA; Spingler B; Mueller B; Shulz G; Lindenmeyer M; Cohen C; Rutkowski JM; Moll S; Scholz CC; Kurtcuoglu V; de Seigneux S
    Nephrol Dial Transplant; 2023 Sep; 38(10):2276-2288. PubMed ID: 37096392
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The Factor Inhibiting HIF Asparaginyl Hydroxylase Regulates Oxidative Metabolism and Accelerates Metabolic Adaptation to Hypoxia.
    Sim J; Cowburn AS; Palazon A; Madhu B; Tyrakis PA; Macías D; Bargiela DM; Pietsch S; Gralla M; Evans CE; Kittipassorn T; Chey YCJ; Branco CM; Rundqvist H; Peet DJ; Johnson RS
    Cell Metab; 2018 Apr; 27(4):898-913.e7. PubMed ID: 29617647
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Prolyl hydroxylase domain protein 3 and asparaginyl hydroxylase factor inhibiting HIF-1 levels are predictive of tumoral behavior and prognosis in hepatocellular carcinoma.
    Ma M; Hua S; Li G; Wang S; Cheng X; He S; Wu P; Chen X
    Oncotarget; 2017 Feb; 8(8):12983-13002. PubMed ID: 28099905
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The Asparagine Hydroxylase FIH: A Unique Oxygen Sensor.
    Volkova YL; Pickel C; Jucht AE; Wenger RH; Scholz CC
    Antioxid Redox Signal; 2022 Nov; 37(13-15):913-935. PubMed ID: 35166119
    [No Abstract]   [Full Text] [Related]  

  • 19. Furan- and Thiophene-2-Carbonyl Amino Acid Derivatives Activate Hypoxia-Inducible Factor via Inhibition of Factor Inhibiting Hypoxia-Inducible Factor-1.
    Kawaguchi SI; Gonda Y; Yamamoto T; Sato Y; Shinohara H; Kobiki Y; Ichimura A; Dan T; Sonoda M; Miyata T; Ogawa A; Tsujita T
    Molecules; 2018 Apr; 23(4):. PubMed ID: 29641495
    [TBL] [Abstract][Full Text] [Related]  

  • 20. FIH permits NAA10 to catalyze the oxygen-dependent lysyl-acetylation of HIF-1α.
    Kang J; Chun YS; Huh J; Park JW
    Redox Biol; 2018 Oct; 19():364-374. PubMed ID: 30237125
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.