BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

298 related articles for article (PubMed ID: 34029087)

  • 21. Biochemistry of the hypoxia-inducible factor hydroxylases.
    Fiorini G; Schofield CJ
    Curr Opin Chem Biol; 2024 Apr; 79():102428. PubMed ID: 38330792
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Factor inhibiting HIF (FIH) recognizes distinct molecular features within hypoxia-inducible factor-α (HIF-α) versus ankyrin repeat substrates.
    Wilkins SE; Karttunen S; Hampton-Smith RJ; Murchland I; Chapman-Smith A; Peet DJ
    J Biol Chem; 2012 Mar; 287(12):8769-81. PubMed ID: 22270367
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Quantitative mass spectrometry reveals dynamics of factor-inhibiting hypoxia-inducible factor-catalyzed hydroxylation.
    Singleton RS; Trudgian DC; Fischer R; Kessler BM; Ratcliffe PJ; Cockman ME
    J Biol Chem; 2011 Sep; 286(39):33784-94. PubMed ID: 21808058
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Proteomics-based identification of novel factor inhibiting hypoxia-inducible factor (FIH) substrates indicates widespread asparaginyl hydroxylation of ankyrin repeat domain-containing proteins.
    Cockman ME; Webb JD; Kramer HB; Kessler BM; Ratcliffe PJ
    Mol Cell Proteomics; 2009 Mar; 8(3):535-46. PubMed ID: 18936059
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Tuning the Transcriptional Response to Hypoxia by Inhibiting Hypoxia-inducible Factor (HIF) Prolyl and Asparaginyl Hydroxylases.
    Chan MC; Ilott NE; Schödel J; Sims D; Tumber A; Lippl K; Mole DR; Pugh CW; Ratcliffe PJ; Ponting CP; Schofield CJ
    J Biol Chem; 2016 Sep; 291(39):20661-73. PubMed ID: 27502280
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Intracellular localisation of human HIF-1 alpha hydroxylases: implications for oxygen sensing.
    Metzen E; Berchner-Pfannschmidt U; Stengel P; Marxsen JH; Stolze I; Klinger M; Huang WQ; Wotzlaw C; Hellwig-Bürgel T; Jelkmann W; Acker H; Fandrey J
    J Cell Sci; 2003 Apr; 116(Pt 7):1319-26. PubMed ID: 12615973
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Inhibition of hypoxia-inducible factor (HIF) hydroxylases by citric acid cycle intermediates: possible links between cell metabolism and stabilization of HIF.
    Koivunen P; Hirsilä M; Remes AM; Hassinen IE; Kivirikko KI; Myllyharju J
    J Biol Chem; 2007 Feb; 282(7):4524-4532. PubMed ID: 17182618
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Differences in hydroxylation and binding of Notch and HIF-1alpha demonstrate substrate selectivity for factor inhibiting HIF-1 (FIH-1).
    Wilkins SE; Hyvärinen J; Chicher J; Gorman JJ; Peet DJ; Bilton RL; Koivunen P
    Int J Biochem Cell Biol; 2009 Jul; 41(7):1563-71. PubMed ID: 19401150
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Asparaginyl hydroxylation of the Notch ankyrin repeat domain by factor inhibiting hypoxia-inducible factor.
    Coleman ML; McDonough MA; Hewitson KS; Coles C; Mecinovic J; Edelmann M; Cook KM; Cockman ME; Lancaster DE; Kessler BM; Oldham NJ; Ratcliffe PJ; Schofield CJ
    J Biol Chem; 2007 Aug; 282(33):24027-38. PubMed ID: 17573339
    [TBL] [Abstract][Full Text] [Related]  

  • 30. The oxygen sensor factor-inhibiting hypoxia-inducible factor-1 controls expression of distinct genes through the bifunctional transcriptional character of hypoxia-inducible factor-1alpha.
    Dayan F; Roux D; Brahimi-Horn MC; Pouyssegur J; Mazure NM
    Cancer Res; 2006 Apr; 66(7):3688-98. PubMed ID: 16585195
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Structure of factor-inhibiting hypoxia-inducible factor 1: An asparaginyl hydroxylase involved in the hypoxic response pathway.
    Dann CE; Bruick RK; Deisenhofer J
    Proc Natl Acad Sci U S A; 2002 Nov; 99(24):15351-6. PubMed ID: 12432100
    [TBL] [Abstract][Full Text] [Related]  

  • 32. The conservation and functionality of the oxygen-sensing enzyme Factor Inhibiting HIF (FIH) in non-vertebrates.
    Hampton-Smith RJ; Davenport BA; Nagarajan Y; Peet DJ
    PLoS One; 2019; 14(4):e0216134. PubMed ID: 31034531
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Screening chelating inhibitors of HIF-prolyl hydroxylase domain 2 (PHD2) and factor inhibiting HIF (FIH).
    Flagg SC; Martin CB; Taabazuing CY; Holmes BE; Knapp MJ
    J Inorg Biochem; 2012 Aug; 113():25-30. PubMed ID: 22687491
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Factor inhibiting HIF-1 (FIH-1) modulates protein interactions of apoptosis-stimulating p53 binding protein 2 (ASPP2).
    Janke K; Brockmeier U; Kuhlmann K; Eisenacher M; Nolde J; Meyer HE; Mairbäurl H; Metzen E
    J Cell Sci; 2013 Jun; 126(Pt 12):2629-40. PubMed ID: 23606740
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Regulation of Transactivation at C-TAD Domain of HIF-1
    Rani S; Roy S; Singh M; Kaithwas G
    Oxid Med Cell Longev; 2022; 2022():2407223. PubMed ID: 35592530
    [TBL] [Abstract][Full Text] [Related]  

  • 36. A dynamic model of the hypoxia-inducible factor 1α (HIF-1α) network.
    Nguyen LK; Cavadas MA; Scholz CC; Fitzpatrick SF; Bruning U; Cummins EP; Tambuwala MM; Manresa MC; Kholodenko BN; Taylor CT; Cheong A
    J Cell Sci; 2013 Mar; 126(Pt 6):1454-63. PubMed ID: 23390316
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Characterization of ankyrin repeat-containing proteins as substrates of the asparaginyl hydroxylase factor inhibiting hypoxia-inducible transcription factor.
    Linke S; Hampton-Smith RJ; Peet DJ
    Methods Enzymol; 2007; 435():61-85. PubMed ID: 17998049
    [TBL] [Abstract][Full Text] [Related]  

  • 38. The zinc chelator, N,N,N',N'-tetrakis (2-pyridylmethyl) ethylenediamine, increases the level of nonfunctional HIF-1alpha protein in normoxic cells.
    Choi SM; Choi KO; Lee N; Oh M; Park H
    Biochem Biophys Res Commun; 2006 May; 343(4):1002-8. PubMed ID: 16579968
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Signalling cross talk of the HIF system: involvement of the FIH protein.
    Coleman ML; Ratcliffe PJ
    Curr Pharm Des; 2009; 15(33):3904-7. PubMed ID: 19671041
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Inverse solvent isotope effects arising from substrate triggering in the factor inhibiting hypoxia inducible factor.
    Hangasky JA; Saban E; Knapp MJ
    Biochemistry; 2013 Mar; 52(9):1594-602. PubMed ID: 23351038
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 15.