223 related articles for article (PubMed ID: 34034619)
41. Combined treatment with auranofin and trametinib induces synergistic apoptosis in breast cancer cells.
Joo MK; Shin S; Ye DJ; An HG; Kwon TU; Baek HS; Kwon YJ; Chun YJ
J Toxicol Environ Health A; 2021 Jan; 84(2):84-94. PubMed ID: 33103613
[TBL] [Abstract][Full Text] [Related]
42. Establishment of a dog primary prostate cancer organoid using the urine cancer stem cells.
Usui T; Sakurai M; Nishikawa S; Umata K; Nemoto Y; Haraguchi T; Itamoto K; Mizuno T; Noguchi S; Mori T; Iwai S; Nakagawa T; Yamawaki H; Ohama T; Sato K
Cancer Sci; 2017 Dec; 108(12):2383-2392. PubMed ID: 29024204
[TBL] [Abstract][Full Text] [Related]
43. Coadministration of Trametinib and Palbociclib Radiosensitizes KRAS-Mutant Non-Small Cell Lung Cancers In Vitro and In Vivo.
Tao Z; Le Blanc JM; Wang C; Zhan T; Zhuang H; Wang P; Yuan Z; Lu B
Clin Cancer Res; 2016 Jan; 22(1):122-33. PubMed ID: 26728409
[TBL] [Abstract][Full Text] [Related]
44. Trametinib with and without pazopanib has potent preclinical activity in thyroid cancer.
Ball DW; Jin N; Xue P; Bhan S; Ahmed SR; Rosen DM; Schayowitz A; Clark DP; Nelkin BD
Oncol Rep; 2015 Nov; 34(5):2319-24. PubMed ID: 26324075
[TBL] [Abstract][Full Text] [Related]
45. Ex vivo culture of tumor cells from N-methyl-N-nitrosourea-induced bladder cancer in rats: Development of organoids and an immortalized cell line.
Yoshida T; Kates M; Sopko NA; Liu X; Singh AK; Bishai WR; Joice G; McConkey DJ; Bivalacqua TJ
Urol Oncol; 2018 Apr; 36(4):160.e23-160.e32. PubMed ID: 29288005
[TBL] [Abstract][Full Text] [Related]
46. Combined mTOR/MEK inhibition prevents proliferation and induces apoptosis in NF2-mutant tumors.
Li N; Lu XY; Shi WY; Mao FJ; Yang XY; Luo YB; Li W
Eur Rev Med Pharmacol Sci; 2019 Jul; 23(13):5874-5883. PubMed ID: 31298338
[TBL] [Abstract][Full Text] [Related]
47. The effect of MEK1/2 inhibitors on cisplatin-induced acute kidney injury (AKI) and cancer growth in mice.
Brown CN; Atwood DJ; Pokhrel D; Ravichandran K; Holditch SJ; Saxena S; Miyazaki M; Nemenoff R; Weiser-Evans MCM; Ljubanovic DG; Joy MS; Edelstein CL
Cell Signal; 2020 Jul; 71():109605. PubMed ID: 32194168
[TBL] [Abstract][Full Text] [Related]
48. Synthetic lethal short hairpin RNA screening reveals that ring finger protein 183 confers resistance to trametinib in colorectal cancer cells.
Geng R; Tan X; Zuo Z; Wu J; Pan Z; Shi W; Liu R; Yao C; Wang G; Lin J; Qiu L; Huang W; Chen S
Chin J Cancer; 2017 Jul; 36(1):63. PubMed ID: 28756770
[TBL] [Abstract][Full Text] [Related]
49. Trametinib Drives T-cell-Dependent Control of KRAS-Mutated Tumors by Inhibiting Pathological Myelopoiesis.
Allegrezza MJ; Rutkowski MR; Stephen TL; Svoronos N; Perales-Puchalt A; Nguyen JM; Payne KK; Singhal S; Eruslanov EB; Tchou J; Conejo-Garcia JR
Cancer Res; 2016 Nov; 76(21):6253-6265. PubMed ID: 27803104
[TBL] [Abstract][Full Text] [Related]
50. Synergistic effect of MEK inhibitor and metformin combination in low grade serous ovarian cancer.
Mert I; Chhina J; Allo G; Dai J; Seward S; Carey MS; Llaurado M; Giri S; Rattan R; Munkarah AR
Gynecol Oncol; 2017 Aug; 146(2):319-326. PubMed ID: 28545687
[TBL] [Abstract][Full Text] [Related]
51. Delayed Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase Inhibition by Trametinib Attenuates Systemic Inflammatory Responses and Multiple Organ Injury in Murine Sepsis.
Smith JA; Mayeux PR; Schnellmann RG
Crit Care Med; 2016 Aug; 44(8):e711-20. PubMed ID: 27031380
[TBL] [Abstract][Full Text] [Related]
52. Dipyridamole Enhances the Cytotoxicities of Trametinib against Colon Cancer Cells through Combined Targeting of HMGCS1 and MEK Pathway.
Zhou S; Xu H; Tang Q; Xia H; Bi F
Mol Cancer Ther; 2020 Jan; 19(1):135-146. PubMed ID: 31554653
[TBL] [Abstract][Full Text] [Related]
53. Ceritinib Enhances the Efficacy of Trametinib in
Verduzco D; Kuenzi BM; Kinose F; Sondak VK; Eroglu Z; Rix U; Smalley KSM
Mol Cancer Ther; 2018 Jan; 17(1):73-83. PubMed ID: 29133622
[TBL] [Abstract][Full Text] [Related]
54. A combinatorial strategy for treating KRAS-mutant lung cancer.
Manchado E; Weissmueller S; Morris JP; Chen CC; Wullenkord R; Lujambio A; de Stanchina E; Poirier JT; Gainor JF; Corcoran RB; Engelman JA; Rudin CM; Rosen N; Lowe SW
Nature; 2016 Jun; 534(7609):647-51. PubMed ID: 27338794
[TBL] [Abstract][Full Text] [Related]
55. A Protocol for Organoids from the Urine of Bladder Cancer Patients.
Walz S; Pollehne P; Geng R; Schneider J; Maas M; Aicher WK; Stenzl A; Amend B; Harland N
Cells; 2023 Aug; 12(17):. PubMed ID: 37681920
[TBL] [Abstract][Full Text] [Related]
56. Exogenous growth factors bFGF, EGF and HGF do not influence viability and phenotype of V600EBRAF melanoma cells and their response to vemurafenib and trametinib in vitro.
Zalesna I; Osrodek M; Hartman ML; Rozanski M; Sztiller-Sikorska M; Niewinna K; Nejc D; Czyz M
PLoS One; 2017; 12(8):e0183498. PubMed ID: 28829835
[TBL] [Abstract][Full Text] [Related]
57. Derivation of a new model of lung adenocarcinoma using canine lung cancer organoids for translational research in pulmonary medicine.
Shiota Sato Y; Elbadawy M; Suzuki K; Tsunedomi R; Nagano H; Ishihara Y; Yamamoto H; Azakami D; Uchide T; Fukushima R; Tanaka R; Yoshida T; Mori T; Abugomaa A; Kaneda M; Yamawaki H; Shinohara Y; Aboubakr M; El-Asrag ME; Usui T; Sasaki K
Biomed Pharmacother; 2023 Sep; 165():115079. PubMed ID: 37413906
[TBL] [Abstract][Full Text] [Related]
58. Factors influencing the CNS distribution of a novel MEK-1/2 inhibitor: implications for combination therapy for melanoma brain metastases.
Vaidhyanathan S; Mittapalli RK; Sarkaria JN; Elmquist WF
Drug Metab Dispos; 2014 Aug; 42(8):1292-300. PubMed ID: 24875464
[TBL] [Abstract][Full Text] [Related]
59. Identification of MAP kinase pathways as therapeutic targets in gallbladder carcinoma using targeted parallel sequencing.
Li M; Chen L; Qu Y; Sui F; Yang Q; Ji M; Shi B; Chen M; Hou P
Oncotarget; 2017 May; 8(22):36319-36330. PubMed ID: 28422736
[TBL] [Abstract][Full Text] [Related]
60. Trametinib, a novel MEK kinase inhibitor, suppresses lipopolysaccharide-induced tumor necrosis factor (TNF)-α production and endotoxin shock.
Shi-Lin D; Yuan X; Zhan S; Luo-Jia T; Chao-Yang T
Biochem Biophys Res Commun; 2015 Mar; 458(3):667-673. PubMed ID: 25684183
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]