227 related articles for article (PubMed ID: 34038402)
1. RHEB/mTOR hyperactivity causes cortical malformations and epileptic seizures through increased axonal connectivity.
Proietti Onori M; Koene LMC; Schäfer CB; Nellist M; de Brito van Velze M; Gao Z; Elgersma Y; van Woerden GM
PLoS Biol; 2021 May; 19(5):e3001279. PubMed ID: 34038402
[TBL] [Abstract][Full Text] [Related]
2. Dendrite growth and the effect of ectopic Rheb expression on cortical neurons.
Sokolov AM; Seluzicki CM; Morton MC; Feliciano DM
Neurosci Lett; 2018 Apr; 671():140-147. PubMed ID: 29447953
[TBL] [Abstract][Full Text] [Related]
3. mTOR Hyperactivity Levels Influence the Severity of Epilepsy and Associated Neuropathology in an Experimental Model of Tuberous Sclerosis Complex and Focal Cortical Dysplasia.
Nguyen LH; Mahadeo T; Bordey A
J Neurosci; 2019 Apr; 39(14):2762-2773. PubMed ID: 30700531
[TBL] [Abstract][Full Text] [Related]
4. A brain somatic RHEB doublet mutation causes focal cortical dysplasia type II.
Zhao S; Li Z; Zhang M; Zhang L; Zheng H; Ning J; Wang Y; Wang F; Zhang X; Gan H; Wang Y; Zhang X; Luo H; Bu G; Xu H; Yao Y; Zhang YW
Exp Mol Med; 2019 Jul; 51(7):1-11. PubMed ID: 31337748
[TBL] [Abstract][Full Text] [Related]
5. Hypervascularization in mTOR-dependent focal and global cortical malformations displays differential rapamycin sensitivity.
Zhang L; Huang T; Teaw S; Bordey A
Epilepsia; 2019 Jun; 60(6):1255-1265. PubMed ID: 31125447
[TBL] [Abstract][Full Text] [Related]
6. A mouse model of DEPDC5-related epilepsy: Neuronal loss of Depdc5 causes dysplastic and ectopic neurons, increased mTOR signaling, and seizure susceptibility.
Yuskaitis CJ; Jones BM; Wolfson RL; Super CE; Dhamne SC; Rotenberg A; Sabatini DM; Sahin M; Poduri A
Neurobiol Dis; 2018 Mar; 111():91-101. PubMed ID: 29274432
[TBL] [Abstract][Full Text] [Related]
7. Persistent Rheb-induced mTORC1 activation in spinal cord neurons induces hypersensitivity in neuropathic pain.
Ma X; Du W; Wang W; Luo L; Huang M; Wang H; Lin R; Li Z; Shi H; Yuan T; Jiang W; Worley PF; Xu T
Cell Death Dis; 2020 Sep; 11(9):747. PubMed ID: 32920594
[TBL] [Abstract][Full Text] [Related]
8. Focal malformations of cortical development: new vistas for molecular pathogenesis.
Lim KC; Crino PB
Neuroscience; 2013 Nov; 252():262-76. PubMed ID: 23892008
[TBL] [Abstract][Full Text] [Related]
9. Anti-seizure gene therapy for focal cortical dysplasia.
Almacellas Barbanoj A; Graham RT; Maffei B; Carpenter JC; Leite M; Hoke J; Hardjo F; Scott-Solache J; Chimonides C; Schorge S; Kullmann DM; Magloire V; Lignani G
Brain; 2024 Feb; 147(2):542-553. PubMed ID: 38100333
[TBL] [Abstract][Full Text] [Related]
10. NPRL3 loss alters neuronal morphology, mTOR localization, cortical lamination and seizure threshold.
Iffland PH; Everett ME; Cobb-Pitstick KM; Bowser LE; Barnes AE; Babus JK; Romanowski AJ; Baybis M; Elziny S; Puffenberger EG; Gonzaga-Jauregui C; Poulopoulos A; Carson VJ; Crino PB
Brain; 2022 Nov; 145(11):3872-3885. PubMed ID: 35136953
[TBL] [Abstract][Full Text] [Related]
11. MicroRNA-199a-5p Induced Autophagy and Inhibits the Pathogenesis of Ankylosing Spondylitis by Modulating the mTOR Signaling via Directly Targeting Ras Homolog Enriched in Brain (Rheb).
Wang Y; Luo J; Wang X; Yang B; Cui L
Cell Physiol Biochem; 2017; 42(6):2481-2491. PubMed ID: 28848090
[TBL] [Abstract][Full Text] [Related]
12. Targeting the Mammalian Target of Rapamycin for Epileptic Encephalopathies and Malformations of Cortical Development.
Jeong A; Wong M
J Child Neurol; 2018 Jan; 33(1):55-63. PubMed ID: 29246093
[TBL] [Abstract][Full Text] [Related]
13. Variation in a range of mTOR-related genes associates with intracranial volume and intellectual disability.
Reijnders MRF; Kousi M; van Woerden GM; Klein M; Bralten J; Mancini GMS; van Essen T; Proietti-Onori M; Smeets EEJ; van Gastel M; Stegmann APA; Stevens SJC; Lelieveld SH; Gilissen C; Pfundt R; Tan PL; Kleefstra T; Franke B; Elgersma Y; Katsanis N; Brunner HG
Nat Commun; 2017 Oct; 8(1):1052. PubMed ID: 29051493
[TBL] [Abstract][Full Text] [Related]
14. mTOR inhibition suppresses established epilepsy in a mouse model of cortical dysplasia.
Nguyen LH; Brewster AL; Clark ME; Regnier-Golanov A; Sunnen CN; Patil VV; D'Arcangelo G; Anderson AE
Epilepsia; 2015 Apr; 56(4):636-46. PubMed ID: 25752454
[TBL] [Abstract][Full Text] [Related]
15. Brain somatic mutations in MTOR cause focal cortical dysplasia type II leading to intractable epilepsy.
Lim JS; Kim WI; Kang HC; Kim SH; Park AH; Park EK; Cho YW; Kim S; Kim HM; Kim JA; Kim J; Rhee H; Kang SG; Kim HD; Kim D; Kim DS; Lee JH
Nat Med; 2015 Apr; 21(4):395-400. PubMed ID: 25799227
[TBL] [Abstract][Full Text] [Related]
16. mTOR signaling in epilepsy: insights from malformations of cortical development.
Crino PB
Cold Spring Harb Perspect Med; 2015 Apr; 5(4):. PubMed ID: 25833943
[TBL] [Abstract][Full Text] [Related]
17. Silencing of RHEB inhibits cell proliferation and promotes apoptosis in colorectal cancer cells via inhibition of the mTOR signaling pathway.
Tian Y; Shen L; Li F; Yang J; Wan X; Ouyang M
J Cell Physiol; 2020 Jan; 235(1):442-453. PubMed ID: 31332784
[TBL] [Abstract][Full Text] [Related]
18. Expression of 4E-BP1 in juvenile mice alleviates mTOR-induced neuronal dysfunction and epilepsy.
Nguyen LH; Xu Y; Mahadeo T; Zhang L; Lin TV; Born HA; Anderson AE; Bordey A
Brain; 2022 May; 145(4):1310-1325. PubMed ID: 34849602
[TBL] [Abstract][Full Text] [Related]
19. Gradient of brain mosaic RHEB variants causes a continuum of cortical dysplasia.
Lee WS; Baldassari S; Chipaux M; Adle-Biassette H; Stephenson SEM; Maixner W; Harvey AS; Lockhart PJ; Baulac S; Leventer RJ
Ann Clin Transl Neurol; 2021 Feb; 8(2):485-490. PubMed ID: 33434304
[TBL] [Abstract][Full Text] [Related]
20. Review: Mechanistic target of rapamycin (mTOR) pathway, focal cortical dysplasia and epilepsy.
Marsan E; Baulac S
Neuropathol Appl Neurobiol; 2018 Feb; 44(1):6-17. PubMed ID: 29359340
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
