BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

337 related articles for article (PubMed ID: 34046031)

  • 1. Myeloid Arginase 1 Insufficiency Exacerbates Amyloid-β Associated Neurodegenerative Pathways and Glial Signatures in a Mouse Model of Alzheimer's Disease: A Targeted Transcriptome Analysis.
    Ma C; Hunt JB; Kovalenko A; Liang H; Selenica MB; Orr MB; Zhang B; Gensel JC; Feola DJ; Gordon MN; Morgan D; Bickford PC; Lee DC
    Front Immunol; 2021; 12():628156. PubMed ID: 34046031
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Arginase 1 Insufficiency Precipitates Amyloid-
    Ma C; Hunt JB; Selenica MB; Sanneh A; Sandusky-Beltran LA; Watler M; Daas R; Kovalenko A; Liang H; Placides D; Cao C; Lin X; Orr MB; Zhang B; Gensel JC; Feola DJ; Gordon MN; Morgan D; Bickford PC; Lee DC
    Front Immunol; 2020; 11():582998. PubMed ID: 33519806
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Human Alzheimer's disease gene expression signatures and immune profile in APP mouse models: a discrete transcriptomic view of Aβ plaque pathology.
    Rothman SM; Tanis KQ; Gandhi P; Malkov V; Marcus J; Pearson M; Stevens R; Gilliland J; Ware C; Mahadomrongkul V; O'Loughlin E; Zeballos G; Smith R; Howell BJ; Klappenbach J; Kennedy M; Mirescu C
    J Neuroinflammation; 2018 Sep; 15(1):256. PubMed ID: 30189875
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Arginase 1+ microglia reduce Aβ plaque deposition during IL-1β-dependent neuroinflammation.
    Cherry JD; Olschowka JA; O'Banion MK
    J Neuroinflammation; 2015 Nov; 12():203. PubMed ID: 26538310
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Novel App knock-in mouse model shows key features of amyloid pathology and reveals profound metabolic dysregulation of microglia.
    Xia D; Lianoglou S; Sandmann T; Calvert M; Suh JH; Thomsen E; Dugas J; Pizzo ME; DeVos SL; Earr TK; Lin CC; Davis S; Ha C; Leung AW; Nguyen H; Chau R; Yulyaningsih E; Lopez I; Solanoy H; Masoud ST; Liang CC; Lin K; Astarita G; Khoury N; Zuchero JY; Thorne RG; Shen K; Miller S; Palop JJ; Garceau D; Sasner M; Whitesell JD; Harris JA; Hummel S; Gnörich J; Wind K; Kunze L; Zatcepin A; Brendel M; Willem M; Haass C; Barnett D; Zimmer TS; Orr AG; Scearce-Levie K; Lewcock JW; Di Paolo G; Sanchez PE
    Mol Neurodegener; 2022 Jun; 17(1):41. PubMed ID: 35690868
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Fibrillar Aβ triggers microglial proteome alterations and dysfunction in Alzheimer mouse models.
    Sebastian Monasor L; Müller SA; Colombo AV; Tanrioever G; König J; Roth S; Liesz A; Berghofer A; Piechotta A; Prestel M; Saito T; Saido TC; Herms J; Willem M; Haass C; Lichtenthaler SF; Tahirovic S
    Elife; 2020 Jun; 9():. PubMed ID: 32510331
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Genetic Ablation of Hematopoietic Cell Kinase Accelerates Alzheimer's Disease-Like Neuropathology in Tg2576 Mice.
    Lim SL; Tran DN; Kieu Z; Chen C; Villanueva E; Ghiaar S; Gallup V; Zumkehr J; Cribbs DH; Rodriguez-Ortiz CJ; Kitazawa M
    Mol Neurobiol; 2020 May; 57(5):2447-2460. PubMed ID: 32146679
    [TBL] [Abstract][Full Text] [Related]  

  • 8. p38α-MAPK-deficient myeloid cells ameliorate symptoms and pathology of APP-transgenic Alzheimer's disease mice.
    Luo Q; Schnöder L; Hao W; Litzenburger K; Decker Y; Tomic I; Menger MD; Liu Y; Fassbender K
    Aging Cell; 2022 Aug; 21(8):e13679. PubMed ID: 35909315
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibition of hematopoietic cell kinase dysregulates microglial function and accelerates early stage Alzheimer's disease-like neuropathology.
    Lim SL; Tran DN; Zumkehr J; Chen C; Ghiaar S; Kieu Z; Villanueva E; Gallup V; Rodriguez-Ortiz CJ; Kitazawa M
    Glia; 2018 Dec; 66(12):2700-2718. PubMed ID: 30277607
    [TBL] [Abstract][Full Text] [Related]  

  • 10. ABCA7 Deficiency Accelerates Amyloid-β Generation and Alzheimer's Neuronal Pathology.
    Sakae N; Liu CC; Shinohara M; Frisch-Daiello J; Ma L; Yamazaki Y; Tachibana M; Younkin L; Kurti A; Carrasquillo MM; Zou F; Sevlever D; Bisceglio G; Gan M; Fol R; Knight P; Wang M; Han X; Fryer JD; Fitzgerald ML; Ohyagi Y; Younkin SG; Bu G; Kanekiyo T
    J Neurosci; 2016 Mar; 36(13):3848-59. PubMed ID: 27030769
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Comparative analysis of transcriptome remodeling in plaque-associated and plaque-distant microglia during amyloid-β pathology progression in mice.
    Hemonnot-Girard AL; Meersseman C; Pastore M; Garcia V; Linck N; Rey C; Chebbi A; Jeanneteau F; Ginsberg SD; Lachuer J; Reynes C; Rassendren F; Hirbec H
    J Neuroinflammation; 2022 Sep; 19(1):234. PubMed ID: 36153535
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Integrative approach to sporadic Alzheimer's disease: deficiency of TYROBP in cerebral Aβ amyloidosis mouse normalizes clinical phenotype and complement subnetwork molecular pathology without reducing Aβ burden.
    Haure-Mirande JV; Wang M; Audrain M; Fanutza T; Kim SH; Heja S; Readhead B; Dudley JT; Blitzer RD; Schadt EE; Zhang B; Gandy S; Ehrlich ME
    Mol Psychiatry; 2019 Mar; 24(3):431-446. PubMed ID: 30283032
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Complement C3 deficiency leads to accelerated amyloid beta plaque deposition and neurodegeneration and modulation of the microglia/macrophage phenotype in amyloid precursor protein transgenic mice.
    Maier M; Peng Y; Jiang L; Seabrook TJ; Carroll MC; Lemere CA
    J Neurosci; 2008 Jun; 28(25):6333-41. PubMed ID: 18562603
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Multiple inflammatory profiles of microglia and altered neuroimages in APP/PS1 transgenic AD mice.
    Liu L; Liu Y; Li N; Huang R; Zheng X; Huang L; Hou S; Yuan Q
    Brain Res Bull; 2020 Mar; 156():86-104. PubMed ID: 31931120
    [TBL] [Abstract][Full Text] [Related]  

  • 15. CHF5074 (CSP-1103) induces microglia alternative activation in plaque-free Tg2576 mice and primary glial cultures exposed to beta-amyloid.
    Porrini V; Lanzillotta A; Branca C; Benarese M; Parrella E; Lorenzini L; Calzà L; Flaibani R; Spano PF; Imbimbo BP; Pizzi M
    Neuroscience; 2015 Aug; 302():112-20. PubMed ID: 25450955
    [TBL] [Abstract][Full Text] [Related]  

  • 16. APP Regulates Microglial Phenotype in a Mouse Model of Alzheimer's Disease.
    Manocha GD; Floden AM; Rausch K; Kulas JA; McGregor BA; Rojanathammanee L; Puig KR; Puig KL; Karki S; Nichols MR; Darland DC; Porter JE; Combs CK
    J Neurosci; 2016 Aug; 36(32):8471-86. PubMed ID: 27511018
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Microglia contributes to plaque growth by cell death due to uptake of amyloid β in the brain of Alzheimer's disease mouse model.
    Baik SH; Kang S; Son SM; Mook-Jung I
    Glia; 2016 Dec; 64(12):2274-2290. PubMed ID: 27658617
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Alzheimer's disease pathology is attenuated in a CD38-deficient mouse model.
    Blacher E; Dadali T; Bespalko A; Haupenthal VJ; Grimm MO; Hartmann T; Lund FE; Stein R; Levy A
    Ann Neurol; 2015 Jul; 78(1):88-103. PubMed ID: 25893674
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Sodium oligomannate alters gut microbiota, reduces cerebral amyloidosis and reactive microglia in a sex-specific manner.
    Bosch ME; Dodiya HB; Michalkiewicz J; Lee C; Shaik SM; Weigle IQ; Zhang C; Osborn J; Nambiar A; Patel P; Parhizkar S; Zhang X; Laury ML; Mondal P; Gomm A; Schipma MJ; Mallah D; Butovsky O; Chang EB; Tanzi RE; Gilbert JA; Holtzman DM; Sisodia SS
    Mol Neurodegener; 2024 Feb; 19(1):18. PubMed ID: 38365827
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Trem2 Deletion Reduces Late-Stage Amyloid Plaque Accumulation, Elevates the Aβ42:Aβ40 Ratio, and Exacerbates Axonal Dystrophy and Dendritic Spine Loss in the PS2APP Alzheimer's Mouse Model.
    Meilandt WJ; Ngu H; Gogineni A; Lalehzadeh G; Lee SH; Srinivasan K; Imperio J; Wu T; Weber M; Kruse AJ; Stark KL; Chan P; Kwong M; Modrusan Z; Friedman BA; Elstrott J; Foreman O; Easton A; Sheng M; Hansen DV
    J Neurosci; 2020 Feb; 40(9):1956-1974. PubMed ID: 31980586
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 17.