BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

127 related articles for article (PubMed ID: 34047349)

  • 1. Functional role of residues involved in substrate binding of human 4-hydroxyphenylpyruvate dioxygenase.
    Huang CW; Hwang CC; Chang YL; Liu JT; Wu SP; Huang KL; Huang WM; Lee HJ
    Biochem J; 2021 Jun; 478(12):2201-2215. PubMed ID: 34047349
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The interactions in the carboxyl terminus of human 4-hydroxyphenylpyruvate dioxygenase are critical to mediate the conformation of the final helix and the tail to shield the active site for catalysis.
    Lin JF; Sheih YL; Chang TC; Chang NY; Chang CW; Shen CP; Lee HJ
    PLoS One; 2013; 8(8):e69733. PubMed ID: 23950902
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The different catalytic roles of the metal-binding ligands in human 4-hydroxyphenylpyruvate dioxygenase.
    Huang CW; Liu HC; Shen CP; Chen YT; Lee SJ; Lloyd MD; Lee HJ
    Biochem J; 2016 May; 473(9):1179-89. PubMed ID: 26936969
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Role of the N-terminus in human 4-hydroxyphenylpyruvate dioxygenase activity.
    Feng AN; Huang CW; Lin CH; Chang YL; Ni MY; Lee HJ
    J Biochem; 2020 Mar; 167(3):315-322. PubMed ID: 31722428
    [TBL] [Abstract][Full Text] [Related]  

  • 5. 4-hydroxyphenylpyruvate dioxygenase catalysis: identification of catalytic residues and production of a hydroxylated intermediate shared with a structurally unrelated enzyme.
    Raspail C; Graindorge M; Moreau Y; Crouzy S; Lefèbvre B; Robin AY; Dumas R; Matringe M
    J Biol Chem; 2011 Jul; 286(29):26061-70. PubMed ID: 21613226
    [TBL] [Abstract][Full Text] [Related]  

  • 6. 4-Hydroxyphenylpyruvate dioxygenase.
    Moran GR
    Arch Biochem Biophys; 2005 Jan; 433(1):117-28. PubMed ID: 15581571
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Free energy calculations elucidate substrate binding, gating mechanism, and tolerance-promoting mutations in herbicide target 4-hydroxyphenylpyruvate dioxygenase.
    Schindler CEM; Hollenbach E; Mietzner T; Schleifer KJ; Zacharias M
    Protein Sci; 2019 Jun; 28(6):1048-1058. PubMed ID: 30945368
    [TBL] [Abstract][Full Text] [Related]  

  • 8. (4-Hydroxyphenyl)pyruvate dioxygenase from Streptomyces avermitilis: the basis for ordered substrate addition.
    Johnson-Winters K; Purpero VM; Kavana M; Nelson T; Moran GR
    Biochemistry; 2003 Feb; 42(7):2072-80. PubMed ID: 12590595
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Intermediate partitioning kinetic isotope effects for the NIH shift of 4-hydroxyphenylpyruvate dioxygenase and the hydroxylation reaction of hydroxymandelate synthase reveal mechanistic complexity.
    Shah DD; Conrad JA; Moran GR
    Biochemistry; 2013 Sep; 52(35):6097-107. PubMed ID: 23941465
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structure of the ferrous form of (4-hydroxyphenyl)pyruvate dioxygenase from Streptomyces avermitilis in complex with the therapeutic herbicide, NTBC.
    Brownlee JM; Johnson-Winters K; Harrison DH; Moran GR
    Biochemistry; 2004 Jun; 43(21):6370-7. PubMed ID: 15157070
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Interaction of (4-hydroxyphenyl)pyruvate dioxygenase with the specific inhibitor 2-[2-nitro-4-(trifluoromethyl)benzoyl]-1,3-cyclohexanedione.
    Kavana M; Moran GR
    Biochemistry; 2003 Sep; 42(34):10238-45. PubMed ID: 12939152
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Crystal structure of Pseudomonas fluorescens 4-hydroxyphenylpyruvate dioxygenase: an enzyme involved in the tyrosine degradation pathway.
    Serre L; Sailland A; Sy D; Boudec P; Rolland A; Pebay-Peyroula E; Cohen-Addad C
    Structure; 1999 Aug; 7(8):977-88. PubMed ID: 10467142
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Rational Redesign of Enzyme via the Combination of Quantum Mechanics/Molecular Mechanics, Molecular Dynamics, and Structural Biology Study.
    Lin HY; Chen X; Dong J; Yang JF; Xiao H; Ye Y; Li LH; Zhan CG; Yang WC; Yang GF
    J Am Chem Soc; 2021 Sep; 143(38):15674-15687. PubMed ID: 34542283
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Improved Herbicide Resistance of 4-Hydroxyphenylpyruvate Dioxygenase from
    Liu B; Wang H; Zhang K; Zhu J; He Q; He J
    J Agric Food Chem; 2020 Nov; 68(44):12365-12374. PubMed ID: 33105985
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Spectroscopic and computational studies of NTBC bound to the non-heme iron enzyme (4-hydroxyphenyl)pyruvate dioxygenase: active site contributions to drug inhibition.
    Neidig ML; Decker A; Kavana M; Moran GR; Solomon EI
    Biochem Biophys Res Commun; 2005 Dec; 338(1):206-14. PubMed ID: 16197918
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Catalytic, noncatalytic, and inhibitory phenomena: kinetic analysis of (4-hydroxyphenyl)pyruvate dioxygenase from Arabidopsis thaliana.
    Purpero VM; Moran GR
    Biochemistry; 2006 May; 45(19):6044-55. PubMed ID: 16681377
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Accumulation of multiple intermediates in the catalytic cycle of (4-hydroxyphenyl)pyruvate dioxygenase from Streptomyces avermitilis.
    Johnson-Winters K; Purpero VM; Kavana M; Moran GR
    Biochemistry; 2005 May; 44(19):7189-99. PubMed ID: 15882057
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structural and functional characterization of 4-hydroxyphenylpyruvate dioxygenase from the thermoacidophilic archaeon Picrophilus torridus.
    Frick E; Spatzal T; Gerhardt S; Krämer A; Einsle O; Hüttel W
    Extremophiles; 2014 Jul; 18(4):641-51. PubMed ID: 24794033
    [TBL] [Abstract][Full Text] [Related]  

  • 19. 4-Hydroxyphenylpyruvate dioxygenase: a hybrid density functional study of the catalytic reaction mechanism.
    Borowski T; Bassan A; Siegbahn PE
    Biochemistry; 2004 Sep; 43(38):12331-42. PubMed ID: 15379572
    [TBL] [Abstract][Full Text] [Related]  

  • 20. 4-Hydroxyphenylpyruvate dioxygenase and hydroxymandelate synthase: exemplars of the α-keto acid dependent oxygenases.
    Moran GR
    Arch Biochem Biophys; 2014 Feb; 544():58-68. PubMed ID: 24211436
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.