135 related articles for article (PubMed ID: 34055235)
1. Leveraging Open Science Drug Development for PET: Preliminary Neuroimaging of
Murrell E; Tong J; Smil D; Kiyota T; Aman AM; Isaac MB; Watson IDG; Vasdev N
ACS Med Chem Lett; 2021 May; 12(5):846-850. PubMed ID: 34055235
[TBL] [Abstract][Full Text] [Related]
2. Leveraging an Open Science Drug Discovery Model to Develop CNS-Penetrant ALK2 Inhibitors for the Treatment of Diffuse Intrinsic Pontine Glioma.
Smil D; Wong JF; Williams EP; Adamson RJ; Howarth A; McLeod DA; Mamai A; Kim S; Wilson BJ; Kiyota T; Aman A; Owen J; Poda G; Horiuchi KY; Kuznetsova E; Ma H; Hamblin JN; Cramp S; Roberts OG; Edwards AM; Uehling D; Al-Awar R; Bullock AN; O'Meara JA; Isaac MB
J Med Chem; 2020 Sep; 63(17):10061-10085. PubMed ID: 32787083
[TBL] [Abstract][Full Text] [Related]
3. ALK2: A Therapeutic Target for Fibrodysplasia Ossificans Progressiva and Diffuse Intrinsic Pontine Glioma.
Sekimata K; Sato T; Sakai N
Chem Pharm Bull (Tokyo); 2020; 68(3):194-200. PubMed ID: 32115526
[TBL] [Abstract][Full Text] [Related]
4. Targeting ALK2: An Open Science Approach to Developing Therapeutics for the Treatment of Diffuse Intrinsic Pontine Glioma.
Ensan D; Smil D; Zepeda-Velázquez CA; Panagopoulos D; Wong JF; Williams EP; Adamson R; Bullock AN; Kiyota T; Aman A; Roberts OG; Edwards AM; O'Meara JA; Isaac MB; Al-Awar R
J Med Chem; 2020 May; 63(9):4978-4996. PubMed ID: 32369358
[TBL] [Abstract][Full Text] [Related]
5. Discovery of Novel Pyrazolopyrimidines as Potent, Selective, and Orally Bioavailable Inhibitors of ALK2.
Nguyen MH; Atasoylu O; Wu L; Kapilashrami K; Pusey M; Gallagher K; Lai CT; Zhao P; Barbosa J; Liu K; He C; Zhang C; Styduhar ED; Witten MR; Chen Y; Lin L; Yang YO; Covington M; Diamond S; Yeleswaram S; Yao W
ACS Med Chem Lett; 2022 Jul; 13(7):1159-1164. PubMed ID: 35859885
[TBL] [Abstract][Full Text] [Related]
6. Recent Advances in ALK2 Inhibitors.
Rooney L; Jones C
ACS Omega; 2021 Aug; 6(32):20729-20734. PubMed ID: 34423181
[TBL] [Abstract][Full Text] [Related]
7. Effects of FKBP12 and type II BMP receptors on signal transduction by ALK2 activating mutations associated with genetic disorders.
Machiya A; Tsukamoto S; Ohte S; Kuratani M; Fujimoto M; Kumagai K; Osawa K; Suda N; Bullock AN; Katagiri T
Bone; 2018 Jun; 111():101-108. PubMed ID: 29551750
[TBL] [Abstract][Full Text] [Related]
8. Bevacizumab Targeting Diffuse Intrinsic Pontine Glioma: Results of 89Zr-Bevacizumab PET Imaging in Brain Tumor Models.
Jansen MH; Lagerweij T; Sewing AC; Vugts DJ; van Vuurden DG; Molthoff CF; Caretti V; Veringa SJ; Petersen N; Carcaboso AM; Noske DP; Vandertop WP; Wesseling P; van Dongen GA; Kaspers GJ; Hulleman E
Mol Cancer Ther; 2016 Sep; 15(9):2166-74. PubMed ID: 27325687
[TBL] [Abstract][Full Text] [Related]
9. Preclinical evaluation of convection-enhanced delivery of liposomal doxorubicin to treat pediatric diffuse intrinsic pontine glioma and thalamic high-grade glioma.
Sewing ACP; Lagerweij T; van Vuurden DG; Meel MH; Veringa SJE; Carcaboso AM; Gaillard PJ; Peter Vandertop W; Wesseling P; Noske D; Kaspers GJL; Hulleman E
J Neurosurg Pediatr; 2017 May; 19(5):518-530. PubMed ID: 28291423
[TBL] [Abstract][Full Text] [Related]
10. Evaluation of
Tinkle CL; Duncan EC; Doubrovin M; Han Y; Li Y; Kim H; Broniscer A; Snyder SE; Merchant TE; Shulkin BL
J Nucl Med; 2019 Mar; 60(3):312-319. PubMed ID: 30072503
[TBL] [Abstract][Full Text] [Related]
11. Discovery of Conformationally Constrained ALK2 Inhibitors.
González-Álvarez H; Ensan D; Xin T; Wong JF; Zepeda-Velázquez CA; Cros J; Sweeney MN; Hoffer L; Kiyota T; Wilson BJ; Aman A; Roberts O; Isaac MB; Bullock AN; Smil D; Al-Awar R
J Med Chem; 2024 Mar; 67(6):4707-4725. PubMed ID: 38498998
[TBL] [Abstract][Full Text] [Related]
12. Development of a human in vitro blood-brain tumor barrier model of diffuse intrinsic pontine glioma to better understand the chemoresistance.
Deligne C; Hachani J; Duban-Deweer S; Meignan S; Leblond P; Carcaboso AM; Sano Y; Shimizu F; Kanda T; Gosselet F; Dehouck MP; Mysiorek C
Fluids Barriers CNS; 2020 Jun; 17(1):37. PubMed ID: 32487241
[TBL] [Abstract][Full Text] [Related]
13. Common mutations in ALK2/ACVR1, a multi-faceted receptor, have roles in distinct pediatric musculoskeletal and neural orphan disorders.
Pacifici M; Shore EM
Cytokine Growth Factor Rev; 2016 Feb; 27():93-104. PubMed ID: 26776312
[TBL] [Abstract][Full Text] [Related]
14. Molecular Drug Imaging:
Jansen MH; Veldhuijzen van Zanten SEM; van Vuurden DG; Huisman MC; Vugts DJ; Hoekstra OS; van Dongen GA; Kaspers GL
J Nucl Med; 2017 May; 58(5):711-716. PubMed ID: 27765855
[TBL] [Abstract][Full Text] [Related]
15. Preclinical evaluation of dasatinib alone and in combination with cabozantinib for the treatment of diffuse intrinsic pontine glioma.
Truffaux N; Philippe C; Paulsson J; Andreiuolo F; Guerrini-Rousseau L; Cornilleau G; Le Dret L; Richon C; Lacroix L; Puget S; Geoerger B; Vassal G; Östman A; Grill J
Neuro Oncol; 2015 Jul; 17(7):953-64. PubMed ID: 25534822
[TBL] [Abstract][Full Text] [Related]
16. Brainstem blood brain barrier disruption using focused ultrasound: A demonstration of feasibility and enhanced doxorubicin delivery.
Alli S; Figueiredo CA; Golbourn B; Sabha N; Wu MY; Bondoc A; Luck A; Coluccia D; Maslink C; Smith C; Wurdak H; Hynynen K; O'Reilly M; Rutka JT
J Control Release; 2018 Jul; 281():29-41. PubMed ID: 29753957
[TBL] [Abstract][Full Text] [Related]
17. ALK2 Receptor Kinase Association with FKBP12.6 Is Structurally Conserved with the ALK2-FKBP12 Complex.
Williams E; Riesebos E; Kerr G; Bullock AN
Biomedicines; 2021 Jan; 9(2):. PubMed ID: 33572801
[TBL] [Abstract][Full Text] [Related]
18. Fostering open collaboration in drug development for paediatric brain tumours.
Wong JF; Brown EJ; Williams E; Bullock AN
Biochem Soc Trans; 2019 Oct; 47(5):1471-1479. PubMed ID: 31551357
[TBL] [Abstract][Full Text] [Related]
19. Biomarker-Based PET Imaging of Diffuse Intrinsic Pontine Glioma in Mouse Models.
Kossatz S; Carney B; Schweitzer M; Carlucci G; Miloushev VZ; Maachani UB; Rajappa P; Keshari KR; Pisapia D; Weber WA; Souweidane MM; Reiner T
Cancer Res; 2017 Apr; 77(8):2112-2123. PubMed ID: 28108511
[TBL] [Abstract][Full Text] [Related]
20. Signal Transduction in Diffuse Intrinsic Pontine Glioma.
Duchatel RJ; Jackson ER; Alvaro F; Nixon B; Hondermarck H; Dun MD
Proteomics; 2019 Nov; 19(21-22):e1800479. PubMed ID: 31328874
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]