251 related articles for article (PubMed ID: 34056752)
1. Drug discovery for X-linked adrenoleukodystrophy: An unbiased screen for compounds that lower very long-chain fatty acids.
Moser AB; Liu Y; Shi X; Schrifl U; Hiebler S; Fatemi A; Braverman NE; Steinberg SJ; Watkins PA
J Cell Biochem; 2021 Oct; 122(10):1337-1349. PubMed ID: 34056752
[TBL] [Abstract][Full Text] [Related]
2. HDAC inhibitor SAHA normalizes the levels of VLCFAs in human skin fibroblasts from X-ALD patients and downregulates the expression of proinflammatory cytokines in Abcd1/2-silenced mouse astrocytes.
Singh J; Khan M; Singh I
J Lipid Res; 2011 Nov; 52(11):2056-69. PubMed ID: 21891797
[TBL] [Abstract][Full Text] [Related]
3. Targeted Brain Delivery of Dendrimer-4-Phenylbutyrate Ameliorates Neurological Deficits in a Long-Term ABCD1-Deficient Mouse Model of X-Linked Adrenoleukodystrophy.
Nemeth CL; Gӧk Ö; Tomlinson SN; Sharma A; Moser AB; Kannan S; Kannan RM; Fatemi A
Neurotherapeutics; 2023 Jan; 20(1):272-283. PubMed ID: 36207570
[TBL] [Abstract][Full Text] [Related]
4. Profiling and Imaging of Phospholipids in Brains of Abcd1-Deficient Mice.
Hama K; Fujiwara Y; Morita M; Yamazaki F; Nakashima Y; Takei S; Takashima S; Setou M; Shimozawa N; Imanaka T; Yokoyama K
Lipids; 2018 Jan; 53(1):85-102. PubMed ID: 29469952
[TBL] [Abstract][Full Text] [Related]
5. Caffeic acid phenethyl ester induces adrenoleukodystrophy (Abcd2) gene in human X-ALD fibroblasts and inhibits the proinflammatory response in Abcd1/2 silenced mouse primary astrocytes.
Singh J; Khan M; Singh I
Biochim Biophys Acta; 2013 Apr; 1831(4):747-58. PubMed ID: 23318275
[TBL] [Abstract][Full Text] [Related]
6. A novel ABCD1 gene mutation causes adrenomyeloneuropathy presenting with spastic paraplegia: A case report.
Liu J; Wang X; Huang D; Qi Y; Xu L; Shao Y
Medicine (Baltimore); 2024 Apr; 103(16):e37874. PubMed ID: 38640304
[TBL] [Abstract][Full Text] [Related]
7. Impaired very long-chain acyl-CoA β-oxidation in human X-linked adrenoleukodystrophy fibroblasts is a direct consequence of ABCD1 transporter dysfunction.
Wiesinger C; Kunze M; Regelsberger G; Forss-Petter S; Berger J
J Biol Chem; 2013 Jun; 288(26):19269-79. PubMed ID: 23671276
[TBL] [Abstract][Full Text] [Related]
8. A report on state-wide implementation of newborn screening for X-linked Adrenoleukodystrophy.
Wiens K; Berry SA; Choi H; Gaviglio A; Gupta A; Hietala A; Kenney-Jung D; Lund T; Miller W; Pierpont EI; Raymond G; Winslow H; Zierhut HA; Orchard PJ
Am J Med Genet A; 2019 Jul; 179(7):1205-1213. PubMed ID: 31074578
[TBL] [Abstract][Full Text] [Related]
9. Management of adrenoleukodystrophy: From pre-clinical studies to the development of new therapies.
Ma CY; Li C; Zhou X; Zhang Z; Jiang H; Liu H; Chen HJ; Tse HF; Liao C; Lian Q
Biomed Pharmacother; 2021 Nov; 143():112214. PubMed ID: 34560537
[TBL] [Abstract][Full Text] [Related]
10. Bezafibrate lowers very long-chain fatty acids in X-linked adrenoleukodystrophy fibroblasts by inhibiting fatty acid elongation.
Engelen M; Schackmann MJ; Ofman R; Sanders RJ; Dijkstra IM; Houten SM; Fourcade S; Pujol A; Poll-The BT; Wanders RJ; Kemp S
J Inherit Metab Dis; 2012 Nov; 35(6):1137-45. PubMed ID: 22447153
[TBL] [Abstract][Full Text] [Related]
11. Beneficial Effects of the Direct AMP-Kinase Activator PXL770 in In Vitro and In Vivo Models of X-Linked Adrenoleukodystrophy.
Monternier PA; Parasar P; Theurey P; Gluais Dagorn P; Kaur N; Nagaraja TN; Fouqueray P; Bolze S; Moller DE; Singh J; Hallakou-Bozec S
J Pharmacol Exp Ther; 2022 Aug; 382(2):208-222. PubMed ID: 35764327
[TBL] [Abstract][Full Text] [Related]
12. Therapeutic potential of deuterium-stabilized (R)-pioglitazone-PXL065-for X-linked adrenoleukodystrophy.
Monternier PA; Singh J; Parasar P; Theurey P; DeWitt S; Jacques V; Klett E; Kaur N; Nagaraja TN; Moller DE; Hallakou-Bozec S
J Inherit Metab Dis; 2022 Jul; 45(4):832-847. PubMed ID: 35510808
[TBL] [Abstract][Full Text] [Related]
13. Metabolic rerouting via SCD1 induction impacts X-linked adrenoleukodystrophy.
Raas Q; van de Beek MC; Forss-Petter S; Dijkstra IM; Deschiffart A; Freshner BC; Stevenson TJ; Jaspers YR; Nagtzaam L; Wanders RJ; van Weeghel M; Engelen-Lee JY; Engelen M; Eichler F; Berger J; Bonkowsky JL; Kemp S
J Clin Invest; 2021 Apr; 131(8):. PubMed ID: 33690217
[TBL] [Abstract][Full Text] [Related]
14. 25-hydroxycholesterol contributes to cerebral inflammation of X-linked adrenoleukodystrophy through activation of the NLRP3 inflammasome.
Jang J; Park S; Jin Hur H; Cho HJ; Hwang I; Pyo Kang Y; Im I; Lee H; Lee E; Yang W; Kang HC; Won Kwon S; Yu JW; Kim DW
Nat Commun; 2016 Oct; 7():13129. PubMed ID: 27779191
[TBL] [Abstract][Full Text] [Related]
15. CYP4F2 affects phenotypic outcome in adrenoleukodystrophy by modulating the clearance of very long-chain fatty acids.
van Engen CE; Ofman R; Dijkstra IM; van Goethem TJ; Verheij E; Varin J; Vidaud M; Wanders RJ; Aubourg P; Kemp S; Barbier M
Biochim Biophys Acta; 2016 Oct; 1862(10):1861-70. PubMed ID: 27425035
[TBL] [Abstract][Full Text] [Related]
16. Clinical, neuroimaging, biochemical, and genetic features in six Chinese patients with Adrenomyeloneuropathy.
Li J; Wang H; He Z; Wang X; Tang J; Huang D
BMC Neurol; 2019 Sep; 19(1):227. PubMed ID: 31526374
[TBL] [Abstract][Full Text] [Related]
17. ABCD1 Transporter Deficiency Results in Altered Cholesterol Homeostasis.
Buda A; Forss-Petter S; Hua R; Jaspers Y; Lassnig M; Waidhofer-Söllner P; Kemp S; Kim P; Weinhofer I; Berger J
Biomolecules; 2023 Aug; 13(9):. PubMed ID: 37759733
[TBL] [Abstract][Full Text] [Related]
18. Case report of dysregulation of primary bile acid synthesis in a family with X-linked adrenoleukodystrophy.
Płatek T; Orso E; Zapała B; Polus A; Kieć-Wilk B; Piwowar M; Chojnacka M; Ciałowicz U; Malczewska-Malec M; Schmitz G; Solnica B; Dembińska-Kieć A
Medicine (Baltimore); 2018 Dec; 97(49):e13353. PubMed ID: 30544401
[TBL] [Abstract][Full Text] [Related]
19. Dendrimer-N-acetyl-L-cysteine modulates monophagocytic response in adrenoleukodystrophy.
Turk BR; Nemeth CL; Marx JS; Tiffany C; Jones R; Theisen B; Kambhampati S; Ramireddy R; Singh S; Rosen M; Kaufman ML; Murray CF; Watkins PA; Kannan S; Kannan R; Fatemi A
Ann Neurol; 2018 Sep; 84(3):452-462. PubMed ID: 30069915
[TBL] [Abstract][Full Text] [Related]
20. Astrocytes and mitochondria from adrenoleukodystrophy protein (ABCD1)-deficient mice reveal that the adrenoleukodystrophy-associated very long-chain fatty acids target several cellular energy-dependent functions.
Kruska N; Schönfeld P; Pujol A; Reiser G
Biochim Biophys Acta; 2015 May; 1852(5):925-36. PubMed ID: 25583114
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]