BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

113 related articles for article (PubMed ID: 34058343)

  • 21. Concurrent inhibition of enzymatic activity and NF-Y-mediated transcription of Topoisomerase-IIα by bis-DemethoxyCurcumin in cancer cells.
    Belluti S; Basile V; Benatti P; Ferrari E; Marverti G; Imbriano C
    Cell Death Dis; 2013 Aug; 4(8):e756. PubMed ID: 23928695
    [TBL] [Abstract][Full Text] [Related]  

  • 22. MiR-599 targeting TOP2A inhibits the malignancy of bladder cancer cells.
    Zhang F; Wu H
    Biochem Biophys Res Commun; 2021 Sep; 570():154-161. PubMed ID: 34284141
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Novel nalidixic acid derivatives targeting topoisomerase II enzyme; Design, synthesis, anticancer activity and effect on cell cycle profile.
    Khalil OM; Gedawy EM; El-Malah AA; Adly ME
    Bioorg Chem; 2019 Mar; 83():262-276. PubMed ID: 30391699
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Proliferation and invasion of colon cancer cells are suppressed by knockdown of TOP2A.
    Zhang R; Xu J; Zhao J; Bai JH
    J Cell Biochem; 2018 Sep; 119(9):7256-7263. PubMed ID: 29761838
    [TBL] [Abstract][Full Text] [Related]  

  • 25. ICBP90, a novel human CCAAT binding protein, involved in the regulation of topoisomerase IIalpha expression.
    Hopfner R; Mousli M; Jeltsch JM; Voulgaris A; Lutz Y; Marin C; Bellocq JP; Oudet P; Bronner C
    Cancer Res; 2000 Jan; 60(1):121-8. PubMed ID: 10646863
    [TBL] [Abstract][Full Text] [Related]  

  • 26. AzaHx, a novel fluorescent, DNA minor groove and G·C recognition element: Synthesis and DNA binding properties of a p-anisyl-4-aza-benzimidazole-pyrrole-imidazole (azaHx-PI) polyamide.
    Satam V; Babu B; Patil P; Brien KA; Olson K; Savagian M; Lee M; Mepham A; Jobe LB; Bingham JP; Pett L; Wang S; Ferrara M; Bruce CD; Wilson WD; Lee M; Hartley JA; Kiakos K
    Bioorg Med Chem Lett; 2015 Sep; 25(17):3681-5. PubMed ID: 26122210
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Higher topoisomerase 2 alpha gene transcript levels predict better prognosis in GBM patients receiving temozolomide chemotherapy: identification of temozolomide as a TOP2A inhibitor.
    Arivazhagan A; Kumar DM; Sagar V; Patric IR; Sridevi S; Thota B; Srividya MR; Prasanna K; Thennarasu K; Mondal N; Hegde AS; Chandramouli BA; Santosh V; Rao MR; Kondaiah P; Somasundaram K
    J Neurooncol; 2012 Apr; 107(2):289-97. PubMed ID: 22102081
    [TBL] [Abstract][Full Text] [Related]  

  • 28. LncRNA FAM230B Promotes Gastric Cancer Growth and Metastasis by Regulating the miR-27a-5p/TOP2A Axis.
    Cui Y; Pu R; Ye J; Huang H; Liao D; Yang Y; Chen W; Yao Y; He Y
    Dig Dis Sci; 2021 Aug; 66(8):2637-2650. PubMed ID: 32910366
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Synthesis and biophysical evaluation of minor-groove binding C-terminus modified pyrrole and imidazole triamide analogs of distamycin.
    Brown T; Taherbhai Z; Sexton J; Sutterfield A; Turlington M; Jones J; Stallings L; Stewart M; Buchmueller K; Mackay H; O'hare C; Kluza J; Nguyen B; Wilson D; Lee M; Hartley JA
    Bioorg Med Chem; 2007 Jan; 15(1):474-83. PubMed ID: 17035029
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Nuclear Transglutaminase 2 interacts with topoisomerase II⍺ to promote DNA damage repair in lung cancer cells.
    Lei X; Cao K; Chen Y; Shen H; Liu Z; Qin H; Cai J; Gao F; Yang Y
    J Exp Clin Cancer Res; 2021 Jul; 40(1):224. PubMed ID: 34225780
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Promoter polymorphisms of TOP2A and ERCC1 genes as predictive factors for chemotherapy in non-small cell lung cancer patients.
    Grenda A; Błach J; Szczyrek M; Krawczyk P; Nicoś M; Kuźnar Kamińska B; Jakimiec M; Balicka G; Chmielewska I; Batura-Gabryel H; Sawicki M; Milanowski J
    Cancer Med; 2020 Jan; 9(2):605-614. PubMed ID: 31797573
    [TBL] [Abstract][Full Text] [Related]  

  • 32. The prognostic significance of topoisomerase II alpha protein in early stage luminal breast cancer.
    An X; Xu F; Luo R; Zheng Q; Lu J; Yang Y; Qin T; Yuan Z; Shi Y; Jiang W; Wang S
    BMC Cancer; 2018 Mar; 18(1):331. PubMed ID: 29587760
    [TBL] [Abstract][Full Text] [Related]  

  • 33. A tri-serine cluster within the topoisomerase IIα-interaction domain of the BLM helicase is required for regulating chromosome breakage in human cells.
    Behnfeldt JH; Acharya S; Tangeman L; Gocha AS; Keirsey J; Groden J
    Hum Mol Genet; 2018 Apr; 27(7):1241-1251. PubMed ID: 29385443
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Genome-wide TOP2A DNA cleavage is biased toward translocated and highly transcribed loci.
    Yu X; Davenport JW; Urtishak KA; Carillo ML; Gosai SJ; Kolaris CP; Byl JAW; Rappaport EF; Osheroff N; Gregory BD; Felix CA
    Genome Res; 2017 Jul; 27(7):1238-1249. PubMed ID: 28385713
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Transcription-associated topoisomerase 2α (TOP2A) activity is a major effector of cytotoxicity induced by G-quadruplex ligands.
    Bossaert M; Pipier A; Riou JF; Noirot C; Nguyên LT; Serre RF; Bouchez O; Defrancq E; Calsou P; Britton S; Gomez D
    Elife; 2021 Jun; 10():. PubMed ID: 34180392
    [TBL] [Abstract][Full Text] [Related]  

  • 36. DNA topoisomerase IIalpha (TOP2A) inhibitors up-regulate fatty acid synthase gene expression in SK-Br3 breast cancer cells: in vitro evidence for a 'functional amplicon' involving FAS, Her-2/neu and TOP2A genes.
    Menendez JA; Vellon L; Lupu R
    Int J Mol Med; 2006 Dec; 18(6):1081-7. PubMed ID: 17089011
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Polyamine-containing etoposide derivatives as poisons of human type II topoisomerases: Differential effects on topoisomerase IIα and IIβ.
    Oviatt AA; Kuriappan JA; Minniti E; Vann KR; Onuorah P; Minarini A; De Vivo M; Osheroff N
    Bioorg Med Chem Lett; 2018 Sep; 28(17):2961-2968. PubMed ID: 30006062
    [TBL] [Abstract][Full Text] [Related]  

  • 38. SPOP is essential for DNA-protein cross-link repair in prostate cancer cells: SPOP-dependent removal of topoisomerase 2A from the topoisomerase 2A-DNA cleavage complex.
    Watanabe R; Maekawa M; Hieda M; Taguchi T; Miura N; Kikugawa T; Saika T; Higashiyama S
    Mol Biol Cell; 2020 Mar; 31(6):478-490. PubMed ID: 31967940
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Dual functions of the homeoprotein DLX4 in modulating responsiveness of tumor cells to topoisomerase II-targeting drugs.
    Trinh BQ; Ko SY; Barengo N; Lin SY; Naora H
    Cancer Res; 2013 Jan; 73(2):1000-10. PubMed ID: 23222298
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Long non‑coding RNA‑DUXAP8 regulates TOP2A in the growth and metastasis of osteosarcoma via microRNA‑635.
    Yang T; Guo JP; Li F; Xiu C; Wang H; Duan XL
    Mol Med Rep; 2021 Jul; 24(1):. PubMed ID: 33982765
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 6.