These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

187 related articles for article (PubMed ID: 34062252)

  • 1. Discovery of dronedarone and its analogues as NLRP3 inflammasome inhibitors with potent anti-inflammation activity.
    Chen H; Chen X; Sun P; Wu D; Yue H; Pan J; Li X; Zhang C; Wu X; Hua L; Hu W; Yang Z
    Bioorg Med Chem Lett; 2021 Aug; 46():128160. PubMed ID: 34062252
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Novel Isoalantolactone-Based Derivatives as Potent NLRP3 Inflammasome Inhibitors: Design, Synthesis, and Biological Characterization.
    Zhao M; Ye N; Liu L; Zhang RJ; Li N; Peng J; Cai XY; Jiang XQ; Su KY; Zhang XL; Rao QR; Liu KJ; Deng DX; Peng AH; Tang MH; Chen LJ; Wu WS; Ye HY
    J Med Chem; 2024 May; 67(9):7516-7538. PubMed ID: 38686671
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Identification of a novel orally bioavailable NLRP3 inflammasome inhibitor.
    Agarwal S; Pethani JP; Shah HA; Vyas V; Sasane S; Bhavsar H; Bandyopadhyay D; Giri P; Viswanathan K; Jain MR; Sharma R
    Bioorg Med Chem Lett; 2020 Nov; 30(21):127571. PubMed ID: 32980515
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Design, Synthesis, and Evaluation of Acrylamide Derivatives as Direct NLRP3 Inflammasome Inhibitors.
    Cocco M; Miglio G; Giorgis M; Garella D; Marini E; Costale A; Regazzoni L; Vistoli G; Orioli M; Massulaha-Ahmed R; Détraz-Durieux I; Groslambert M; Py BF; Bertinaria M
    ChemMedChem; 2016 Aug; 11(16):1790-803. PubMed ID: 26990578
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Hydrogen-Rich Saline Attenuated Subarachnoid Hemorrhage-Induced Early Brain Injury in Rats by Suppressing Inflammatory Response: Possible Involvement of NF-κB Pathway and NLRP3 Inflammasome.
    Shao A; Wu H; Hong Y; Tu S; Sun X; Wu Q; Zhao Q; Zhang J; Sheng J
    Mol Neurobiol; 2016 Jul; 53(5):3462-3476. PubMed ID: 26091790
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Discovery of benzo[cd]indol-2-one and benzylidene-thiazolidine-2,4-dione as new classes of NLRP3 inflammasome inhibitors via ER-β structure based virtual screening.
    Abdullaha M; Ali M; Kour D; Kumar A; Bharate SB
    Bioorg Chem; 2020 Jan; 95():103500. PubMed ID: 31869665
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Discovery of Novel Pterostilbene-Based Derivatives as Potent and Orally Active NLRP3 Inflammasome Inhibitors with Inflammatory Activity for Colitis.
    Chen LZ; Zhang XX; Liu MM; Wu J; Ma D; Diao LZ; Li Q; Huang YS; Zhang R; Ruan BF; Liu XH
    J Med Chem; 2021 Sep; 64(18):13633-13657. PubMed ID: 34506712
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis and biological evaluation of parthenolide derivatives with reduced toxicity as potential inhibitors of the NLRP3 inflammasome.
    Ou Y; Sun P; Wu N; Chen H; Wu D; Hu W; Yang Z
    Bioorg Med Chem Lett; 2020 Sep; 30(17):127399. PubMed ID: 32738997
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Efficacy and Pharmacology of the NLRP3 Inflammasome Inhibitor CP-456,773 (CRID3) in Murine Models of Dermal and Pulmonary Inflammation.
    Primiano MJ; Lefker BA; Bowman MR; Bree AG; Hubeau C; Bonin PD; Mangan M; Dower K; Monks BG; Cushing L; Wang S; Guzova J; Jiao A; Lin LL; Latz E; Hepworth D; Hall JP
    J Immunol; 2016 Sep; 197(6):2421-33. PubMed ID: 27521339
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Comparison of Inhibitory Capacities of 6-, 8- and 10-Gingerols/Shogaols on the Canonical NLRP3 Inflammasome-Mediated IL-1β Secretion.
    Ho SC; Chang YH
    Molecules; 2018 Feb; 23(2):. PubMed ID: 29466287
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Estradiol inhibits NLRP3 inflammasome in fibroblast-like synoviocytes activated by lipopolysaccharide and adenosine triphosphate.
    Shi J; Zhao W; Ying H; Zhang Y; Du J; Chen S; Li J; Shen B
    Int J Rheum Dis; 2018 Nov; 21(11):2002-2010. PubMed ID: 29105345
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Development of small molecule inhibitors targeting NLRP3 inflammasome pathway for inflammatory diseases.
    Zhang X; Xu A; Lv J; Zhang Q; Ran Y; Wei C; Wu J
    Eur J Med Chem; 2020 Jan; 185():111822. PubMed ID: 31699536
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis and Biological Evaluation of Novel Benzimidazole Derivatives and Analogs Targeting the NLRP3 Inflammasome.
    Pan L; Hang N; Zhang C; Chen Y; Li S; Sun Y; Li Z; Meng X
    Molecules; 2017 Jan; 22(2):. PubMed ID: 28146092
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Direct Binding to NLRP3 Pyrin Domain as a Novel Strategy to Prevent NLRP3-Driven Inflammation and Gouty Arthritis.
    Yang G; Lee HE; Moon SJ; Ko KM; Koh JH; Seok JK; Min JK; Heo TH; Kang HC; Cho YY; Lee HS; Fitzgerald KA; Lee JY
    Arthritis Rheumatol; 2020 Jul; 72(7):1192-1202. PubMed ID: 32134203
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Chalcones Display Anti-NLRP3 Inflammasome Activity in Macrophages through Inhibition of Both Priming and Activation Steps-Structure-Activity-Relationship and Mechanism Studies.
    Leu WJ; Chu JC; Hsu JL; Du CM; Jiang YH; Hsu LC; Huang WJ; Guh JH
    Molecules; 2020 Dec; 25(24):. PubMed ID: 33339319
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Interleukin-1 and the Inflammasome as Therapeutic Targets in Cardiovascular Disease.
    Abbate A; Toldo S; Marchetti C; Kron J; Van Tassell BW; Dinarello CA
    Circ Res; 2020 Apr; 126(9):1260-1280. PubMed ID: 32324502
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Naloxone inhibits nod-like receptor protein 3 inflammasome.
    Lin HY; Chang YY; Kao MC; Huang CJ
    J Surg Res; 2017 Nov; 219():72-77. PubMed ID: 29078913
    [TBL] [Abstract][Full Text] [Related]  

  • 18. OLT1177, a β-sulfonyl nitrile compound, safe in humans, inhibits the NLRP3 inflammasome and reverses the metabolic cost of inflammation.
    Marchetti C; Swartzwelter B; Gamboni F; Neff CP; Richter K; Azam T; Carta S; Tengesdal I; Nemkov T; D'Alessandro A; Henry C; Jones GS; Goodrich SA; St Laurent JP; Jones TM; Scribner CL; Barrow RB; Altman RD; Skouras DB; Gattorno M; Grau V; Janciauskiene S; Rubartelli A; Joosten LAB; Dinarello CA
    Proc Natl Acad Sci U S A; 2018 Feb; 115(7):E1530-E1539. PubMed ID: 29378952
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Sendai Virus V Protein Inhibits the Secretion of Interleukin-1β by Preventing NLRP3 Inflammasome Assembly.
    Komatsu T; Tanaka Y; Kitagawa Y; Koide N; Naiki Y; Morita N; Gotoh B; Yokochi T
    J Virol; 2018 Oct; 92(19):. PubMed ID: 30021903
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Intermedin
    Wu D; Shi L; Li P; Ni X; Zhang J; Zhu Q; Qi Y; Wang B
    Inflammation; 2018 Mar; 41(2):505-514. PubMed ID: 29192367
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.