173 related articles for article (PubMed ID: 34063139)
1. A Validated LC-MS/MS Assay for the Simultaneous Quantification of the FDA-Approved Anticancer Mixture (Encorafenib and Binimetinib): Metabolic Stability Estimation.
Attwa MW; Darwish HW; Al-Shakliah NS; Kadi AA
Molecules; 2021 May; 26(9):. PubMed ID: 34063139
[TBL] [Abstract][Full Text] [Related]
2. A Rapid and Sensitive Liquid Chromatography-Tandem Mass Spectrometry Bioanalytical Method for the Quantification of Encorafenib and Binimetinib as a First-Line Treatment for Advanced (Unresectable or Metastatic) Melanoma-Application to a Pharmacokinetic Study.
Hefnawy MM; Alanazi MM; Al-Hossaini AM; Alnasser AI; El-Azab AS; Jardan YAB; Attwa MW; El-Gendy MA
Molecules; 2022 Dec; 28(1):. PubMed ID: 36615272
[TBL] [Abstract][Full Text] [Related]
3. Metabolic Stability Assessment of New PARP Inhibitor Talazoparib Using Validated LC-MS/MS Methodology: In silico Metabolic Vulnerability and Toxicity Studies.
Attwa MW; Kadi AA; Abdelhameed AS; Alhazmi HA
Drug Des Devel Ther; 2020; 14():783-793. PubMed ID: 32158196
[TBL] [Abstract][Full Text] [Related]
4. Estimation of zorifertinib metabolic stability in human liver microsomes using LC-MS/MS.
Attwa MW; Al-Shakliah NS; AlRabiah H; Kadi AA; Abdelhameed AS
J Pharm Biomed Anal; 2022 Mar; 211():114626. PubMed ID: 35123331
[TBL] [Abstract][Full Text] [Related]
5. Development and Validation of a Rapid LC-MS/MS Method for Quantifying Alvocidib: In Silico and In Vitro Metabolic Stability Estimation in Human Liver Microsomes.
Attwa MW; AlRabiah H; Kadi AA
Molecules; 2023 Mar; 28(5):. PubMed ID: 36903615
[TBL] [Abstract][Full Text] [Related]
6. LC-MS/MS method for the quantification of the anti-cancer agent infigratinib: Application for estimation of metabolic stability in human liver microsomes.
Mostafa GAE; Kadi AA; AlMasoud N; Attwa MW; Al-Shakliah NS; AlRabiah H
J Chromatogr B Analyt Technol Biomed Life Sci; 2021 Aug; 1179():122806. PubMed ID: 34325312
[TBL] [Abstract][Full Text] [Related]
7. LC-MS/MS Estimation of Rociletinib Levels in Human Liver Microsomes: Application to Metabolic Stability Estimation.
Attwa MW; Abdelhameed AS; Kadi AA
Drug Des Devel Ther; 2021; 15():3915-3925. PubMed ID: 34552321
[TBL] [Abstract][Full Text] [Related]
8. Assessment of In Silico and In Vitro Selpercatinib Metabolic Stability in Human Liver Microsomes Using a Validated LC-MS/MS Method.
Attwa MW; AlRabiah H; Mostafa GAE; Bakheit AH; Kadi AA
Molecules; 2023 Mar; 28(6):. PubMed ID: 36985590
[TBL] [Abstract][Full Text] [Related]
9. LC-MS/MS Estimation of the Anti-Cancer Agent Tandutinib Levels in Human Liver Microsomes: Metabolic Stability Evaluation Assay.
Attwa MW; Abdelhameed AS; Al-Shakliah NS; Kadi AA
Drug Des Devel Ther; 2020; 14():4439-4449. PubMed ID: 33122888
[TBL] [Abstract][Full Text] [Related]
10. Development of an LC-MS/MS Method for Quantification of Sapitinib in Human Liver Microsomes: In Silico and In Vitro Metabolic Stability Evaluation.
Attwa MW; AlRabiah H; Mostafa GAE; Kadi AA
Molecules; 2023 Mar; 28(5):. PubMed ID: 36903565
[TBL] [Abstract][Full Text] [Related]
11. A validated LC-MS/MS analytical method for the quantification of pemigatinib: metabolic stability evaluation in human liver microsomes.
Attwa MW; Abdelhameed AS; Alsaif NA; Kadi AA; AlRabiah H
RSC Adv; 2022 Jul; 12(31):20387-20394. PubMed ID: 35919584
[TBL] [Abstract][Full Text] [Related]
12. Encorafenib and Binimetinib: First Global Approvals.
Shirley M
Drugs; 2018 Aug; 78(12):1277-1284. PubMed ID: 30117021
[TBL] [Abstract][Full Text] [Related]
13. Evaluation of Alectinib Metabolic Stability in HLMs Using Fast LC-MS/MS Method: In Silico ADME Profile, P450 Metabolic Lability, and Toxic Alerts Screening.
Attwa MW; AlRabiah H; Mostafa GAE; Kadi AA
Pharmaceutics; 2023 Oct; 15(10):. PubMed ID: 37896209
[TBL] [Abstract][Full Text] [Related]
14. Overall survival in patients with BRAF-mutant melanoma receiving encorafenib plus binimetinib versus vemurafenib or encorafenib (COLUMBUS): a multicentre, open-label, randomised, phase 3 trial.
Dummer R; Ascierto PA; Gogas HJ; Arance A; Mandala M; Liszkay G; Garbe C; Schadendorf D; Krajsova I; Gutzmer R; Chiarion Sileni V; Dutriaux C; de Groot JWB; Yamazaki N; Loquai C; Moutouh-de Parseval LA; Pickard MD; Sandor V; Robert C; Flaherty KT
Lancet Oncol; 2018 Oct; 19(10):1315-1327. PubMed ID: 30219628
[TBL] [Abstract][Full Text] [Related]
15. Identification of Iminium Intermediates Generation in the Metabolism of Tepotinib Using LC-MS/MS: In Silico and Practical Approaches to Bioactivation Pathway Elucidation.
Abdelhameed AS; Attwa MW; Kadi AA
Molecules; 2020 Oct; 25(21):. PubMed ID: 33126762
[TBL] [Abstract][Full Text] [Related]
16. Encorafenib and binimetinib for the treatment of BRAF V600E/K-mutated melanoma.
Rose AAN
Drugs Today (Barc); 2019 Apr; 55(4):247-264. PubMed ID: 31050693
[TBL] [Abstract][Full Text] [Related]
17. Encorafenib plus binimetinib versus vemurafenib or encorafenib in patients with BRAF-mutant melanoma (COLUMBUS): a multicentre, open-label, randomised phase 3 trial.
Dummer R; Ascierto PA; Gogas HJ; Arance A; Mandala M; Liszkay G; Garbe C; Schadendorf D; Krajsova I; Gutzmer R; Chiarion-Sileni V; Dutriaux C; de Groot JWB; Yamazaki N; Loquai C; Moutouh-de Parseval LA; Pickard MD; Sandor V; Robert C; Flaherty KT
Lancet Oncol; 2018 May; 19(5):603-615. PubMed ID: 29573941
[TBL] [Abstract][Full Text] [Related]
18. Validated LC-MS/MS assay for quantification of the newly approved tyrosine kinase inhibitor, dacomitinib, and application to investigating its metabolic stability.
Abdelhameed AS; Kadi AA; Attwa MW; AlRabiah H
PLoS One; 2019; 14(4):e0214598. PubMed ID: 30947315
[TBL] [Abstract][Full Text] [Related]
19. Quantification of the irreversible fibroblast growth factor receptor inhibitor futibatinib by UPLC-MS/MS: Application to the metabolic stability assay in human liver microsomes for the estimation of its in vitro hepatic intrinsic clearance.
Tang LWT; Chan ECY
J Pharm Biomed Anal; 2022 May; 214():114731. PubMed ID: 35325798
[TBL] [Abstract][Full Text] [Related]
20. Rapid LC-MS/MS Bosutinib Quantification with Applications in Metabolic Stability Estimation.
Attwa MW; Alanazi MM
Molecules; 2023 Feb; 28(4):. PubMed ID: 36838629
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
