BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

728 related articles for article (PubMed ID: 34064886)

  • 1. A Whole-Body Physiologically Based Pharmacokinetic Model Characterizing Interplay of OCTs and MATEs in Intestine, Liver and Kidney to Predict Drug-Drug Interactions of Metformin with Perpetrators.
    Yang Y; Zhang Z; Li P; Kong W; Liu X; Liu L
    Pharmaceutics; 2021 May; 13(5):. PubMed ID: 34064886
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mechanistic in vitro studies confirm that inhibition of the renal apical efflux transporter multidrug and toxin extrusion (MATE) 1, and not altered absorption, underlies the increased metformin exposure observed in clinical interactions with cimetidine, trimethoprim or pyrimethamine.
    Elsby R; Chidlaw S; Outteridge S; Pickering S; Radcliffe A; Sullivan R; Jones H; Butler P
    Pharmacol Res Perspect; 2017 Oct; 5(5):. PubMed ID: 28971610
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Metformin and cimetidine: Physiologically based pharmacokinetic modelling to investigate transporter mediated drug-drug interactions.
    Burt HJ; Neuhoff S; Almond L; Gaohua L; Harwood MD; Jamei M; Rostami-Hodjegan A; Tucker GT; Rowland-Yeo K
    Eur J Pharm Sci; 2016 Jun; 88():70-82. PubMed ID: 27019345
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Ondansetron can enhance cisplatin-induced nephrotoxicity via inhibition of multiple toxin and extrusion proteins (MATEs).
    Li Q; Guo D; Dong Z; Zhang W; Zhang L; Huang SM; Polli JE; Shu Y
    Toxicol Appl Pharmacol; 2013 Nov; 273(1):100-9. PubMed ID: 24001450
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Irinotecan Alters the Disposition of Morphine Via Inhibition of Organic Cation Transporter 1 (OCT1) and 2 (OCT2).
    Zhu P; Ye Z; Guo D; Xiong Z; Huang S; Guo J; Zhang W; Polli JE; Zhou H; Li Q; Shu Y
    Pharm Res; 2018 Oct; 35(12):243. PubMed ID: 30361780
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Competitive inhibition of the luminal efflux by multidrug and toxin extrusions, but not basolateral uptake by organic cation transporter 2, is the likely mechanism underlying the pharmacokinetic drug-drug interactions caused by cimetidine in the kidney.
    Ito S; Kusuhara H; Yokochi M; Toyoshima J; Inoue K; Yuasa H; Sugiyama Y
    J Pharmacol Exp Ther; 2012 Feb; 340(2):393-403. PubMed ID: 22072731
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Moxifloxacin Is a Potent In Vitro Inhibitor of OCT- and MATE-Mediated Transport of Metformin and Ethambutol.
    Te Brake LH; van den Heuvel JJ; Buaben AO; van Crevel R; Bilos A; Russel FG; Aarnoutse RE; Koenderink JB
    Antimicrob Agents Chemother; 2016 Dec; 60(12):7105-7114. PubMed ID: 27645247
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Selective Inhibition on Organic Cation Transporters by Carvedilol Protects Mice from Cisplatin-Induced Nephrotoxicity.
    Guo D; Yang H; Li Q; Bae HJ; Obianom O; Zeng S; Su T; Polli JE; Shu Y
    Pharm Res; 2018 Sep; 35(11):204. PubMed ID: 30191328
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Bile duct ligation differently regulates protein expressions of organic cation transporters in intestine, liver and kidney of rats through activation of farnesoid X receptor by cholate and bilirubin.
    Hong S; Li S; Meng X; Li P; Wang X; Su M; Liu X; Liu L
    Acta Pharm Sin B; 2023 Jan; 13(1):227-245. PubMed ID: 36815051
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Proguanil and cycloguanil are organic cation transporter and multidrug and toxin extrusion substrates.
    van der Velden M; Bilos A; van den Heuvel JJMW; Rijpma SR; Hurkmans EGE; Sauerwein RW; Russel FGM; Koenderink JB
    Malar J; 2017 Oct; 16(1):422. PubMed ID: 29061131
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Divergent Regulation of OCT and MATE Drug Transporters by Cadmium Exposure.
    Yang H; Zhou S; Guo D; Obianom ON; Li Q; Shu Y
    Pharmaceutics; 2021 Apr; 13(4):. PubMed ID: 33924306
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Organic cation transporter OCTs (SLC22) and MATEs (SLC47) in the human kidney.
    Motohashi H; Inui K
    AAPS J; 2013 Apr; 15(2):581-8. PubMed ID: 23435786
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Enhanced Intestinal Permeability and Plasma Concentration of Metformin in Rats by the Repeated Administration of Red Ginseng Extract.
    Jin S; Lee S; Jeon JH; Kim H; Choi MK; Song IS
    Pharmaceutics; 2019 Apr; 11(4):. PubMed ID: 31003498
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A Physiologically-Based Pharmacokinetic Model of Trimethoprim for MATE1, OCT1, OCT2, and CYP2C8 Drug-Drug-Gene Interaction Predictions.
    Türk D; Hanke N; Lehr T
    Pharmaceutics; 2020 Nov; 12(11):. PubMed ID: 33182761
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Genetic variation in organic cation transporters and considerations in drug development.
    Varma MVS
    Expert Opin Drug Metab Toxicol; 2023 Mar; 19(3):149-164. PubMed ID: 37070463
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Prediction of drug-drug interaction potential mediated by transporters between dasatinib and metformin, pravastatin, and rosuvastatin using physiologically based pharmacokinetic modeling.
    Chang M; Bathena S; Christopher LJ; Shen H; Roy A
    Cancer Chemother Pharmacol; 2022 Mar; 89(3):383-392. PubMed ID: 35147740
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Pharmacogenetic variation and metformin response.
    Chen S; Zhou J; Xi M; Jia Y; Wong Y; Zhao J; Ding L; Zhang J; Wen A
    Curr Drug Metab; 2013 Dec; 14(10):1070-82. PubMed ID: 24329113
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Different effect of testosterone and oestrogen on urinary excretion of metformin via regulating OCTs and MATEs expression in the kidney of mice.
    He R; Ai L; Zhang D; Wan L; Zheng T; Yin J; Lu H; Lu J; Lu F; Liu F; Jia W
    J Cell Mol Med; 2016 Dec; 20(12):2309-2317. PubMed ID: 27469532
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Characterization of cytochrome P450 (CYP) 2D6 drugs as substrates of human organic cation transporters and multidrug and toxin extrusion proteins.
    Neul C; Hofmann U; Schaeffeler E; Winter S; Klein K; Giacomini KM; Eichelbaum M; Schwab M; Nies AT
    Br J Pharmacol; 2021 Mar; 178(6):1459-1474. PubMed ID: 33434947
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Inhibitory Effects of Green Tea and (-)-Epigallocatechin Gallate on Transport by OATP1B1, OATP1B3, OCT1, OCT2, MATE1, MATE2-K and P-Glycoprotein.
    Knop J; Misaka S; Singer K; Hoier E; Müller F; Glaeser H; König J; Fromm MF
    PLoS One; 2015; 10(10):e0139370. PubMed ID: 26426900
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 37.