These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

263 related articles for article (PubMed ID: 34065773)

  • 1. Design, Synthesis, and Anticancer Screening for Repurposed Pyrazolo[3,4-d]pyrimidine Derivatives on Four Mammalian Cancer Cell Lines.
    Othman EM; Bekhit AA; Anany MA; Dandekar T; Ragab HM; Wahid A
    Molecules; 2021 May; 26(10):. PubMed ID: 34065773
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Novel Pyrazolo[3,4-d]pyrimidines as Potential Cytotoxic Agents: Design, Synthesis, Molecular Docking and CDK2 Inhibition.
    Maher M; Kassab AE; Zaher AF; Mahmoud Z
    Anticancer Agents Med Chem; 2019; 19(11):1368-1381. PubMed ID: 31038080
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis of new pyrazolo[3,4-d]pyrimidine derivatives and evaluation of their anti-inflammatory and anticancer activities.
    Abd El Razik HA; Mroueh M; Faour WH; Shebaby WN; Daher CF; Ashour HMA; Ragab HM
    Chem Biol Drug Des; 2017 Jul; 90(1):83-96. PubMed ID: 28032452
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Design, synthesis and anticancer evaluation of 1H-pyrazolo[3,4-d]pyrimidine derivatives as potent EGFR
    Gaber AA; Bayoumi AH; El-Morsy AM; Sherbiny FF; Mehany ABM; Eissa IH
    Bioorg Chem; 2018 Oct; 80():375-395. PubMed ID: 29986185
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis, EGFR Inhibition and Anti-cancer Activity of New 3,6-dimethyl-1-phenyl-4-(substituted-methoxy)pyrazolo[3,4-d] pyrimidine Derivatives.
    Bakr RB; Mehany ABM; Abdellatif KRA
    Anticancer Agents Med Chem; 2017; 17(10):1389-1400. PubMed ID: 28270084
    [TBL] [Abstract][Full Text] [Related]  

  • 6. New pyrazolopyrimidine derivatives with anticancer activity: Design, synthesis, PIM-1 inhibition, molecular docking study and molecular dynamics.
    Philoppes JN; Khedr MA; Hassan MHA; Kamel G; Lamie PF
    Bioorg Chem; 2020 Jul; 100():103944. PubMed ID: 32450389
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Molecular docking approach for the design and synthesis of new pyrazolopyrimidine analogs of roscovitine as potential CDK2 inhibitors endowed with pronounced anticancer activity.
    Hamed OA; Abou-Elmagd El-Sayed N; Mahmoud WR; F Elmasry G
    Bioorg Chem; 2024 Jun; 147():107413. PubMed ID: 38696844
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Novel pyrazolo[3,4-d]pyrimidine derivatives inhibit human cancer cell proliferation and induce apoptosis by ROS generation.
    Gaonkar S; Savanur MA; Nadaf AA; Najare MS; Mantur S; Garbhagudi M; Mulla SI; Khazi IAM
    Arch Pharm (Weinheim); 2020 Apr; 353(4):e1900296. PubMed ID: 32073686
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Some pyrazole and pyrazolo[3,4-d]pyrimidine derivatives: synthesis and anticancer evaluation.
    Shamroukh AH; Rashad AE; Abdel-Megeid RE; Ali HS; Ali MM
    Arch Pharm (Weinheim); 2014 Aug; 347(8):559-65. PubMed ID: 24801813
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Pyrazolo[3,4-d]pyrimidine-based dual EGFR T790M/HER2 inhibitors: Design, synthesis, structure-activity relationship and biological activity as potential antitumor and anticonvulsant agents.
    Lamie PF; El-Kalaawy AM; Abdel Latif NS; Rashed LA; Philoppes JN
    Eur J Med Chem; 2021 Mar; 214():113222. PubMed ID: 33545637
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Rational design, molecular docking and synthesis of novel homopiperazine linked imidazo[1,2-a]pyrimidine derivatives as potent cytotoxic and antimicrobial agents.
    Mantipally M; Gangireddy MR; Gundla R; Badavath VN; Mandha SR; Maddipati VC
    Bioorg Med Chem Lett; 2019 Aug; 29(16):2248-2253. PubMed ID: 31239178
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Design, synthesis and biological evaluation of certain CDK2 inhibitors based on pyrazole and pyrazolo[1,5-a] pyrimidine scaffold with apoptotic activity.
    Ali GME; Ibrahim DA; Elmetwali AM; Ismail NSM
    Bioorg Chem; 2019 May; 86():1-14. PubMed ID: 30682722
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cytotoxic and Apoptotic Effects of Novel Pyrrolo[2,3-d]Pyrimidine Derivatives Containing Urea Moieties on Cancer Cell Lines.
    Kilic-Kurt Z; Bakar-Ates F; Karakas B; Kütük Ö
    Anticancer Agents Med Chem; 2018; 18(9):1303-1312. PubMed ID: 29866023
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Discovery of novel pyrrolopyrimidine/pyrazolopyrimidine derivatives bearing 1,2,3-triazole moiety as c-Met kinase inhibitors.
    Wang L; Liu X; Duan Y; Li X; Zhao B; Wang C; Xiao Z; Zheng P; Tang Q; Zhu W
    Chem Biol Drug Des; 2018 Jul; 92(1):1301-1314. PubMed ID: 29575727
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Design, synthesis, anticancer evaluation, molecular docking and cell cycle analysis of 3-methyl-4,7-dihydropyrazolo[1,5-a]pyrimidine derivatives as potent histone lysine demethylases (KDM) inhibitors and apoptosis inducers.
    Metwally NH; Mohamed MS; Ragb EA
    Bioorg Chem; 2019 Jul; 88():102929. PubMed ID: 31015179
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis, anticancer evaluation, and molecular docking studies of some novel 4,6-disubstituted pyrazolo[3,4-d]pyrimidines as cyclin-dependent kinase 2 (CDK2) inhibitors.
    Cherukupalli S; Chandrasekaran B; Kryštof V; Aleti RR; Sayyad N; Merugu SR; Kushwaha ND; Karpoormath R
    Bioorg Chem; 2018 Sep; 79():46-59. PubMed ID: 29753773
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Benzimidazole-linked pyrazolo[1,5-a]pyrimidine conjugates: synthesis and detail evaluation as potential anticancer agents.
    Bagul C; Rao GK; Veena I; Kulkarni R; Tamboli JR; Akunuri R; Shaik SP; Pal-Bhadra M; Kamal A
    Mol Divers; 2023 Jun; 27(3):1185-1202. PubMed ID: 36114912
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis, biological evaluation, drug-likeness, and in silico screening of novel benzylidene-hydrazone analogues as small molecule anticancer agents.
    Alam MS; Lee DU
    Arch Pharm Res; 2016 Feb; 39(2):191-201. PubMed ID: 26694484
    [TBL] [Abstract][Full Text] [Related]  

  • 19. One-pot synthesis of thiazolo[3,2-a]pyrimidine derivatives, their cytotoxic evaluation and molecular docking studies.
    Sekhar T; Thriveni P; Venkateswarlu A; Daveedu T; Peddanna K; Sainath SB
    Spectrochim Acta A Mol Biomol Spectrosc; 2020 Apr; 231():118056. PubMed ID: 32006911
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and biological evaluation of pyrazolo[4,3-d]pyrimidine analogues.
    Yuan L; Song C; Li C; Li Y; Dong L; Yin S
    Eur J Med Chem; 2013 Sep; 67():152-7. PubMed ID: 23851116
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.