216 related articles for article (PubMed ID: 34067359)
1. DNMT3A Mutation-Induced CDK1 Overexpression Promotes Leukemogenesis by Modulating the Interaction between EZH2 and DNMT3A.
Yang Y; Dai Y; Yang X; Wu S; Wang Y
Biomolecules; 2021 May; 11(6):. PubMed ID: 34067359
[No Abstract] [Full Text] [Related]
2. DNMT3A mutation promotes leukemia development through NAM-NAD metabolic reprogramming.
Yang X; Wang X; Yang Y; Li Z; Chen Y; Shang S; Wang Y
J Transl Med; 2023 Jul; 21(1):481. PubMed ID: 37464424
[TBL] [Abstract][Full Text] [Related]
3. Conditional knockin of Dnmt3a R878H initiates acute myeloid leukemia with mTOR pathway involvement.
Dai YJ; Wang YY; Huang JY; Xia L; Shi XD; Xu J; Lu J; Su XB; Yang Y; Zhang WN; Wang PP; Wu SF; Huang T; Mi JQ; Han ZG; Chen Z; Chen SJ
Proc Natl Acad Sci U S A; 2017 May; 114(20):5237-5242. PubMed ID: 28461508
[No Abstract] [Full Text] [Related]
4. Cooperation of Dnmt3a R878H with Nras G12D promotes leukemogenesis in knock-in mice: a pilot study.
Shi X; Yang Y; Shang S; Wu S; Zhang W; Peng L; Huang T; Zhang R; Ren R; Mi J; Wang Y
BMC Cancer; 2019 Nov; 19(1):1072. PubMed ID: 31703632
[TBL] [Abstract][Full Text] [Related]
5. DNMT3A R882H mutation promotes acute leukemic cell survival by regulating glycolysis through the NRF2/NQO1 axis.
Chu X; Zhong L; Dan W; Wang X; Zhang Z; Liu Z; Lu Y; Shao X; Zhou Z; Chen S; Liu B
Cell Signal; 2023 May; 105():110626. PubMed ID: 36758683
[TBL] [Abstract][Full Text] [Related]
6. Genetic and Epigenetic Perturbations by DNMT3A-R882 Mutants Impaired Apoptosis through Augmentation of PRDX2 in Myeloid Leukemia Cells.
Bera R; Chiu MC; Huang YJ; Liang DC; Lee YS; Shih LY
Neoplasia; 2018 Nov; 20(11):1106-1120. PubMed ID: 30245403
[TBL] [Abstract][Full Text] [Related]
7. Mutations in the DNMT3A DNA methyltransferase in acute myeloid leukemia patients cause both loss and gain of function and differential regulation by protein partners.
Sandoval JE; Huang YH; Muise A; Goodell MA; Reich NO
J Biol Chem; 2019 Mar; 294(13):4898-4910. PubMed ID: 30705090
[TBL] [Abstract][Full Text] [Related]
8. DNMT3A R882H mutation drives daunorubicin resistance in acute myeloid leukemia via regulating NRF2/NQO1 pathway.
Chu X; Zhong L; Dan W; Wang X; Zhang Z; Liu Z; Lu Y; Shao X; Zhou Z; Chen S; Liu B
Cell Commun Signal; 2022 Oct; 20(1):168. PubMed ID: 36303144
[TBL] [Abstract][Full Text] [Related]
9. Study on the Immune Escape Mechanism of Acute Myeloid Leukemia With DNMT3A Mutation.
Que Y; Li H; Lin L; Zhu X; Xiao M; Wang Y; Zhu L; Li D
Front Immunol; 2021; 12():653030. PubMed ID: 34093541
[TBL] [Abstract][Full Text] [Related]
10. DNMT3A mutation leads to leukemic extramedullary infiltration mediated by TWIST1.
Xu J; Zhang W; Yan XJ; Lin XQ; Li W; Mi JQ; Li JM; Zhu J; Chen Z; Chen SJ
J Hematol Oncol; 2016 Oct; 9(1):106. PubMed ID: 27724883
[TBL] [Abstract][Full Text] [Related]
11. DOT1L as a therapeutic target for the treatment of DNMT3A-mutant acute myeloid leukemia.
Rau RE; Rodriguez BA; Luo M; Jeong M; Rosen A; Rogers JH; Campbell CT; Daigle SR; Deng L; Song Y; Sweet S; Chevassut T; Andreeff M; Kornblau SM; Li W; Goodell MA
Blood; 2016 Aug; 128(7):971-81. PubMed ID: 27335278
[TBL] [Abstract][Full Text] [Related]
12. Novel impact of the DNMT3A R882H mutation on GSH metabolism in a K562 cell model established by TALENs.
Yang L; Liu Y; Zhang N; Ding X; Zhang W; Shen K; Huang L; Zhou J; Cui S; Zhu Z; Hu Z; Xiao M
Oncotarget; 2017 May; 8(18):30395-30409. PubMed ID: 28418922
[TBL] [Abstract][Full Text] [Related]
13. Epigenetic Perturbations by Arg882-Mutated DNMT3A Potentiate Aberrant Stem Cell Gene-Expression Program and Acute Leukemia Development.
Lu R; Wang P; Parton T; Zhou Y; Chrysovergis K; Rockowitz S; Chen WY; Abdel-Wahab O; Wade PA; Zheng D; Wang GG
Cancer Cell; 2016 Jul; 30(1):92-107. PubMed ID: 27344947
[TBL] [Abstract][Full Text] [Related]
14. Loss of the histone methyltransferase EZH2 induces resistance to multiple drugs in acute myeloid leukemia.
Göllner S; Oellerich T; Agrawal-Singh S; Schenk T; Klein HU; Rohde C; Pabst C; Sauer T; Lerdrup M; Tavor S; Stölzel F; Herold S; Ehninger G; Köhler G; Pan KT; Urlaub H; Serve H; Dugas M; Spiekermann K; Vick B; Jeremias I; Berdel WE; Hansen K; Zelent A; Wickenhauser C; Müller LP; Thiede C; Müller-Tidow C
Nat Med; 2017 Jan; 23(1):69-78. PubMed ID: 27941792
[TBL] [Abstract][Full Text] [Related]
15. Down-regulation of lncRNA NEAT1 regulated by miR-194-5p/DNMT3A facilitates acute myeloid leukemia.
Duan MY; Li M; Tian H; Tang G; Yang YC; Peng NC
Blood Cells Mol Dis; 2020 May; 82():102417. PubMed ID: 32179410
[TBL] [Abstract][Full Text] [Related]
16. Biologico-clinical significance of DNMT3A variants expression in acute myeloid leukemia.
Lin N; Fu W; Zhao C; Li B; Yan X; Li Y
Biochem Biophys Res Commun; 2017 Dec; 494(1-2):270-277. PubMed ID: 29024628
[TBL] [Abstract][Full Text] [Related]
17. Acute myeloid leukemia with DNMT3A mutations.
Li Y; Zhu B
Leuk Lymphoma; 2014 Sep; 55(9):2002-12. PubMed ID: 24283755
[TBL] [Abstract][Full Text] [Related]
18. Bioinformatics Analysis Identifies Key Genes and Pathways in Acute Myeloid Leukemia Associated with DNMT3A Mutation.
Chen S; Chen Y; Lu J; Yuan D; He L; Tan H; Xu L
Biomed Res Int; 2020; 2020():9321630. PubMed ID: 33299888
[TBL] [Abstract][Full Text] [Related]
19. A Model System for Studying the DNMT3A Hotspot Mutation (DNMT3A
Lu R; Wang J; Ren Z; Yin J; Wang Y; Cai L; Wang GG
Cancer Res; 2019 Jul; 79(14):3583-3594. PubMed ID: 31164355
[TBL] [Abstract][Full Text] [Related]
20. DNMT3A in Leukemia.
Brunetti L; Gundry MC; Goodell MA
Cold Spring Harb Perspect Med; 2017 Feb; 7(2):. PubMed ID: 28003281
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
