These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

487 related articles for article (PubMed ID: 34069681)

  • 1. Global Genomic Analysis of SARS-CoV-2 RNA Dependent RNA Polymerase Evolution and Antiviral Drug Resistance.
    Mari A; Roloff T; Stange M; Søgaard KK; Asllanaj E; Tauriello G; Alexander LT; Schweitzer M; Leuzinger K; Gensch A; Martinez AE; Bielicki J; Pargger H; Siegemund M; Nickel CH; Bingisser R; Osthoff M; Bassetti S; Sendi P; Battegay M; Marzolini C; Seth-Smith HMB; Schwede T; Hirsch HH; Egli A
    Microorganisms; 2021 May; 9(5):. PubMed ID: 34069681
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Transient SARS-CoV-2 RNA-Dependent RNA Polymerase Mutations after Remdesivir Treatment for Chronic COVID-19 in Two Transplant Recipients: Case Report and Intra-Host Viral Genomic Investigation.
    Yang S; Multani A; Garrigues JM; Oh MS; Hemarajata P; Burleson T; Green NM; Oliai C; Gaynor PT; Beaird OE; Winston DJ; Seet CS; Schaenman JM
    Microorganisms; 2023 Aug; 11(8):. PubMed ID: 37630656
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Plant-Derived Natural Non-Nucleoside Analog Inhibitors (NNAIs) against
    Naidu SAG; Mustafa G; Clemens RA; Naidu AS
    J Diet Suppl; 2023; 20(2):254-283. PubMed ID: 34850656
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structural Basis of the Potential Binding Mechanism of Remdesivir to SARS-CoV-2 RNA-Dependent RNA Polymerase.
    Zhang L; Zhou R
    J Phys Chem B; 2020 Aug; 124(32):6955-6962. PubMed ID: 32521159
    [TBL] [Abstract][Full Text] [Related]  

  • 5. In silico analysis of RNA-dependent RNA polymerase of the SARS-CoV-2 and therapeutic potential of existing antiviral drugs.
    Mondal SK; Mukhoty S; Kundu H; Ghosh S; Sen MK; Das S; Brogi S
    Comput Biol Med; 2021 Aug; 135():104591. PubMed ID: 34216889
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Denovo designing, retro-combinatorial synthesis, and molecular dynamics analysis identify novel antiviral VTRM1.1 against RNA-dependent RNA polymerase of SARS CoV2 virus.
    Tiwari V
    Int J Biol Macromol; 2021 Feb; 171():358-365. PubMed ID: 33421473
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Remdesivir is a direct-acting antiviral that inhibits RNA-dependent RNA polymerase from severe acute respiratory syndrome coronavirus 2 with high potency.
    Gordon CJ; Tchesnokov EP; Woolner E; Perry JK; Feng JY; Porter DP; Götte M
    J Biol Chem; 2020 May; 295(20):6785-6797. PubMed ID: 32284326
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structural Basis for RNA Replication by the SARS-CoV-2 Polymerase.
    Wang Q; Wu J; Wang H; Gao Y; Liu Q; Mu A; Ji W; Yan L; Zhu Y; Zhu C; Fang X; Yang X; Huang Y; Gao H; Liu F; Ge J; Sun Q; Yang X; Xu W; Liu Z; Yang H; Lou Z; Jiang B; Guddat LW; Gong P; Rao Z
    Cell; 2020 Jul; 182(2):417-428.e13. PubMed ID: 32526208
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structure-Based Virtual Screening to Identify Novel Potential Compound as an Alternative to Remdesivir to Overcome the RdRp Protein Mutations in SARS-CoV-2.
    Kumar D T; Shaikh N; Kumar S U; Doss C GP; Zayed H
    Front Mol Biosci; 2021; 8():645216. PubMed ID: 33898520
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Revealing the Inhibition Mechanism of RNA-Dependent RNA Polymerase (RdRp) of SARS-CoV-2 by Remdesivir and Nucleotide Analogues: A Molecular Dynamics Simulation Study.
    Wakchaure PD; Ghosh S; Ganguly B
    J Phys Chem B; 2020 Nov; 124(47):10641-10652. PubMed ID: 33190493
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Two conserved oligomer interfaces of NSP7 and NSP8 underpin the dynamic assembly of SARS-CoV-2 RdRP.
    Biswal M; Diggs S; Xu D; Khudaverdyan N; Lu J; Fang J; Blaha G; Hai R; Song J
    Nucleic Acids Res; 2021 Jun; 49(10):5956-5966. PubMed ID: 33999154
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Effects of natural polymorphisms in SARS-CoV-2 RNA-dependent RNA polymerase on its activity and sensitivity to inhibitors in vitro.
    Miropolskaya N; Kozlov M; Petushkov I; Prostova M; Pupov D; Esyunina D; Kochetkov S; Kulbachinskiy A
    Biochimie; 2023 Mar; 206():81-88. PubMed ID: 36252889
    [TBL] [Abstract][Full Text] [Related]  

  • 13. RNA dependent RNA polymerase (RdRp) as a drug target for SARS-CoV2.
    Mishra A; Rathore AS
    J Biomol Struct Dyn; 2022 Aug; 40(13):6039-6051. PubMed ID: 33491569
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Fast and efficient purification of SARS-CoV-2 RNA dependent RNA polymerase complex expressed in Escherichia coli.
    Madru C; Tekpinar AD; Rosario S; Czernecki D; Brûlé S; Sauguet L; Delarue M
    PLoS One; 2021; 16(4):e0250610. PubMed ID: 33914787
    [TBL] [Abstract][Full Text] [Related]  

  • 15. High-throughput rational design of the remdesivir binding site in the RdRp of SARS-CoV-2: implications for potential resistance.
    Padhi AK; Shukla R; Saudagar P; Tripathi T
    iScience; 2021 Jan; 24(1):101992. PubMed ID: 33490902
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Genetic Study of SARS-CoV-2 Non Structural Protein 12 in COVID-19 Patients Non Responders to Remdesivir.
    Santos Bravo M; Alonso R; Soria D; Sánchez Palomino S; Sanzo Machuca Á; Rodríguez C; Alcamí J; Díez-Fuertes F; Simarro Redon À; Hurtado JC; Fernández Avilés F; Bodro M; Rubio E; Villanueva JL; Vergara A; Castro P; Tuset M; Cuesta G; Puerta P; García C; Mosquera Gutiérrez MDM; Martínez MJ; Vila J; Soriano A; Marcos MÁ
    Microbiol Spectr; 2022 Dec; 10(6):e0244822. PubMed ID: 36354320
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Remdesivir Strongly Binds to Both RNA-Dependent RNA Polymerase and Main Protease of SARS-CoV-2: Evidence from Molecular Simulations.
    Nguyen HL; Thai NQ; Truong DT; Li MS
    J Phys Chem B; 2020 Dec; 124(50):11337-11348. PubMed ID: 33264025
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The antiviral compound remdesivir potently inhibits RNA-dependent RNA polymerase from Middle East respiratory syndrome coronavirus.
    Gordon CJ; Tchesnokov EP; Feng JY; Porter DP; Götte M
    J Biol Chem; 2020 Apr; 295(15):4773-4779. PubMed ID: 32094225
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structure of replicating SARS-CoV-2 polymerase.
    Hillen HS; Kokic G; Farnung L; Dienemann C; Tegunov D; Cramer P
    Nature; 2020 Aug; 584(7819):154-156. PubMed ID: 32438371
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Assessing Genomic Mutations in SARS-CoV-2: Potential Resistance to Antiviral Drugs in Viral Populations from Untreated COVID-19 Patients.
    Lombardo D; Musolino C; Chines V; Caminiti G; Palermo C; Cacciola I; Raffa G; Pollicino T
    Microorganisms; 2023 Dec; 12(1):. PubMed ID: 38276171
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 25.