These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

182 related articles for article (PubMed ID: 34077515)

  • 1. Small molecule 1a reduces FMRpolyG-mediated toxicity in in vitro and in vivo models for FMR1 premutation.
    Haify SN; Buijsen RAM; Verwegen L; Severijnen LWFM; de Boer H; Boumeester V; Monshouwer R; Yang WY; Cameron MD; Willemsen R; Disney MD; Hukema RK
    Hum Mol Genet; 2021 Aug; 30(17):1632-1648. PubMed ID: 34077515
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Presence of inclusions positive for polyglycine containing protein, FMRpolyG, indicates that repeat-associated non-AUG translation plays a role in fragile X-associated primary ovarian insufficiency.
    Buijsen RA; Visser JA; Kramer P; Severijnen EA; Gearing M; Charlet-Berguerand N; Sherman SL; Berman RF; Willemsen R; Hukema RK
    Hum Reprod; 2016 Jan; 31(1):158-68. PubMed ID: 26537920
    [TBL] [Abstract][Full Text] [Related]  

  • 3. FMRpolyG alters mitochondrial transcripts level and respiratory chain complex assembly in Fragile X associated tremor/ataxia syndrome [FXTAS].
    Gohel D; Sripada L; Prajapati P; Singh K; Roy M; Kotadia D; Tassone F; Charlet-Berguerand N; Singh R
    Biochim Biophys Acta Mol Basis Dis; 2019 Jun; 1865(6):1379-1388. PubMed ID: 30771487
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Astroglial-targeted expression of the fragile X CGG repeat premutation in mice yields RAN translation, motor deficits and possible evidence for cell-to-cell propagation of FXTAS pathology.
    Wenzel HJ; Murray KD; Haify SN; Hunsaker MR; Schwartzer JJ; Kim K; La Spada AR; Sopher BL; Hagerman PJ; Raske C; Severijnen LWFM; Willemsen R; Hukema RK; Berman RF
    Acta Neuropathol Commun; 2019 Feb; 7(1):27. PubMed ID: 30808398
    [TBL] [Abstract][Full Text] [Related]  

  • 5. FMRpolyG accumulates in FMR1 premutation granulosa cells.
    Friedman-Gohas M; Elizur SE; Dratviman-Storobinsky O; Aizer A; Haas J; Raanani H; Orvieto R; Cohen Y
    J Ovarian Res; 2020 Feb; 13(1):22. PubMed ID: 32101156
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Translation of Expanded CGG Repeats into FMRpolyG Is Pathogenic and May Contribute to Fragile X Tremor Ataxia Syndrome.
    Sellier C; Buijsen RAM; He F; Natla S; Jung L; Tropel P; Gaucherot A; Jacobs H; Meziane H; Vincent A; Champy MF; Sorg T; Pavlovic G; Wattenhofer-Donze M; Birling MC; Oulad-Abdelghani M; Eberling P; Ruffenach F; Joint M; Anheim M; Martinez-Cerdeno V; Tassone F; Willemsen R; Hukema RK; Viville S; Martinat C; Todd PK; Charlet-Berguerand N
    Neuron; 2017 Jan; 93(2):331-347. PubMed ID: 28065649
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Neuropathology of RAN translation proteins in fragile X-associated tremor/ataxia syndrome.
    Krans A; Skariah G; Zhang Y; Bayly B; Todd PK
    Acta Neuropathol Commun; 2019 Oct; 7(1):152. PubMed ID: 31665086
    [TBL] [Abstract][Full Text] [Related]  

  • 8. RAN translation at CGG repeats induces ubiquitin proteasome system impairment in models of fragile X-associated tremor ataxia syndrome.
    Oh SY; He F; Krans A; Frazer M; Taylor JP; Paulson HL; Todd PK
    Hum Mol Genet; 2015 Aug; 24(15):4317-26. PubMed ID: 25954027
    [TBL] [Abstract][Full Text] [Related]  

  • 9. What has been learned from mouse models of the Fragile X Premutation and Fragile X-associated tremor/ataxia syndrome?
    Foote MM; Careaga M; Berman RF
    Clin Neuropsychol; 2016 Aug; 30(6):960-72. PubMed ID: 27355912
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Reversibility of neuropathology and motor deficits in an inducible mouse model for FXTAS.
    Hukema RK; Buijsen RA; Schonewille M; Raske C; Severijnen LA; Nieuwenhuizen-Bakker I; Verhagen RF; van Dessel L; Maas A; Charlet-Berguerand N; De Zeeuw CI; Hagerman PJ; Berman RF; Willemsen R
    Hum Mol Genet; 2015 Sep; 24(17):4948-57. PubMed ID: 26060190
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Characterization and Early Detection of Balance Deficits in Fragile X Premutation Carriers With and Without Fragile X-Associated Tremor/Ataxia Syndrome (FXTAS).
    O'Keefe JA; Robertson-Dick E; Dunn EJ; Li Y; Deng Y; Fiutko AN; Berry-Kravis E; Hall DA
    Cerebellum; 2015 Dec; 14(6):650-62. PubMed ID: 25763861
    [TBL] [Abstract][Full Text] [Related]  

  • 12. CGG repeat-associated translation mediates neurodegeneration in fragile X tremor ataxia syndrome.
    Todd PK; Oh SY; Krans A; He F; Sellier C; Frazer M; Renoux AJ; Chen KC; Scaglione KM; Basrur V; Elenitoba-Johnson K; Vonsattel JP; Louis ED; Sutton MA; Taylor JP; Mills RE; Charlet-Berguerand N; Paulson HL
    Neuron; 2013 May; 78(3):440-55. PubMed ID: 23602499
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Static and dynamic postural control deficits in aging fragile X mental retardation 1 (FMR1) gene premutation carriers.
    Wang Z; Khemani P; Schmitt LM; Lui S; Mosconi MW
    J Neurodev Disord; 2019 Jan; 11(1):2. PubMed ID: 30665341
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Cyclic mismatch binding ligands interact with disease-associated CGG trinucleotide repeats in RNA and suppress their translation.
    Konieczny P; Mukherjee S; Stepniak-Konieczna E; Taylor K; Niewiadomska D; Piasecka A; Walczak A; Baud A; Dohno C; Nakatani K; Sobczak K
    Nucleic Acids Res; 2021 Sep; 49(16):9479-9495. PubMed ID: 34358321
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Potential pathogenic mechanisms underlying Fragile X Tremor Ataxia Syndrome: RAN translation and/or RNA gain-of-function?
    Boivin M; Willemsen R; Hukema RK; Sellier C
    Eur J Med Genet; 2018 Nov; 61(11):674-679. PubMed ID: 29223504
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Fragile X-associated tremor/ataxia syndrome: influence of the FMR1 gene on motor fiber tracts in males with normal and premutation alleles.
    Wang JY; Hessl D; Schneider A; Tassone F; Hagerman RJ; Rivera SM
    JAMA Neurol; 2013 Aug; 70(8):1022-9. PubMed ID: 23753897
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The fragile X-associated tremor ataxia syndrome.
    Tassone F; Hagerman R
    Results Probl Cell Differ; 2012; 54():337-57. PubMed ID: 22009361
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Repeat-associated non-AUG (RAN) translation and other molecular mechanisms in Fragile X Tremor Ataxia Syndrome.
    Glineburg MR; Todd PK; Charlet-Berguerand N; Sellier C
    Brain Res; 2018 Aug; 1693(Pt A):43-54. PubMed ID: 29453961
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Selective rescue of heightened anxiety but not gait ataxia in a premutation 90CGG mouse model of Fragile X-associated tremor/ataxia syndrome.
    Castro H; Kul E; Buijsen RAM; Severijnen LWFM; Willemsen R; Hukema RK; Stork O; Santos M
    Hum Mol Genet; 2017 Jun; 26(11):2133-2145. PubMed ID: 28369393
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mouse models of fragile X-associated tremor ataxia.
    Berman RF; Willemsen R
    J Investig Med; 2009 Dec; 57(8):837-41. PubMed ID: 19574928
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.