These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

168 related articles for article (PubMed ID: 34077738)

  • 1. C118P, a novel microtubule inhibitor with anti-angiogenic and vascular disrupting activities, exerts anti-tumor effects against hepatocellular carcinoma.
    Yang M; Su Y; Wang Z; Du D; Wei S; Liao Z; Zhang Q; Zhao L; Zhang X; Han L; Jiang J; Zhan M; Sun L; Yuan S; Zhou Z
    Biochem Pharmacol; 2021 Aug; 190():114641. PubMed ID: 34077738
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Preclinical Pharmacokinetics of C118P, a Novel Prodrug of Microtubules Inhibitor and Its Metabolite C118 in Mice, Rats, and Dogs.
    Zhang C; Zhang X; Wang G; Peng Y; Zhang X; Wu H; Yu B; Sun J
    Molecules; 2018 Nov; 23(11):. PubMed ID: 30400617
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Tivantinib induces G2/M arrest and apoptosis by disrupting tubulin polymerization in hepatocellular carcinoma.
    Xiang Q; Zhen Z; Deng DY; Wang J; Chen Y; Li J; Zhang Y; Wang F; Chen N; Chen H; Chen Y
    J Exp Clin Cancer Res; 2015 Oct; 34():118. PubMed ID: 26458953
    [TBL] [Abstract][Full Text] [Related]  

  • 4. YSL-12, a novel microtubule-destabilizing agent, exerts potent anti-tumor activity against colon cancer in vitro and in vivo.
    Cai D; Qiu Z; Yao W; Liu Y; Huang H; Liao S; Luo Q; Xie L; Lin Z
    Cancer Chemother Pharmacol; 2016 Jun; 77(6):1217-29. PubMed ID: 27107592
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A novel synthetic compound exerts effective anti-tumour activity in vivo via the inhibition of tubulin polymerisation in A549 cells.
    Yan J; Pang Y; Sheng J; Wang Y; Chen J; Hu J; Huang L; Li X
    Biochem Pharmacol; 2015 Sep; 97(1):51-61. PubMed ID: 26212540
    [TBL] [Abstract][Full Text] [Related]  

  • 6. MIL-1, a novel antitumor agent derived from natural product millepachine, acts as tubulin polymerization inhibitor for the treatment of hepatocellular carcinoma.
    Yan J; Zhuang Q; Li Z; Xiong Y; He M; Kang C; Zhang Q; Han L; Liang E; Liu H; Ke P; Huang X
    Eur J Pharmacol; 2021 May; 898():173975. PubMed ID: 33647258
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Deoxypodophyllotoxin exerts both anti-angiogenic and vascular disrupting effects.
    Jiang Z; Wu M; Miao J; Duan H; Zhang S; Chen M; Sun L; Wang Y; Zhang X; Zhu X; Zhang L
    Int J Biochem Cell Biol; 2013 Aug; 45(8):1710-9. PubMed ID: 23702033
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A new diaryl urea compound, D181, induces cell cycle arrest in the G1 and M phases by targeting receptor tyrosine kinases and the microtubule skeleton.
    Zhang J; Zhou J; Ren X; Diao Y; Li H; Jiang H; Ding K; Pei D
    Invest New Drugs; 2012 Apr; 30(2):490-507. PubMed ID: 21080210
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The Novel Nature Microtubule Inhibitor Ivalin Induces G2/M Arrest and Apoptosis in Human Hepatocellular Carcinoma SMMC-7721 Cells In Vitro.
    Liu F; Lin S; Zhang C; Ma J; Han Z; Jia F; Xie W; Li X
    Medicina (Kaunas); 2019 Aug; 55(8):. PubMed ID: 31409007
    [No Abstract]   [Full Text] [Related]  

  • 10. Anti-angiogenic and vascular disrupting effects of C9, a new microtubule-depolymerizing agent.
    Ren X; Dai M; Lin LP; Li PK; Ding J
    Br J Pharmacol; 2009 Apr; 156(8):1228-38. PubMed ID: 19302593
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Apatinib targets both tumor and endothelial cells in hepatocellular carcinoma.
    Yang C; Qin S
    Cancer Med; 2018 Sep; 7(9):4570-4583. PubMed ID: 30109780
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Identification of DW532 as a novel anti-tumor agent targeting both kinases and tubulin.
    Peng T; Wu JR; Tong LJ; Li MY; Chen F; Leng YX; Qu R; Han K; Su Y; Chen Y; Duan WH; Xie H; Ding J
    Acta Pharmacol Sin; 2014 Jul; 35(7):916-28. PubMed ID: 24858311
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Azaindole derivatives are inhibitors of microtubule dynamics, with anti-cancer and anti-angiogenic activities.
    Prudent R; Vassal-Stermann É; Nguyen CH; Mollaret M; Viallet J; Desroches-Castan A; Martinez A; Barette C; Pillet C; Valdameri G; Soleilhac E; Di Pietro A; Feige JJ; Billaud M; Florent JC; Lafanechère L
    Br J Pharmacol; 2013 Feb; 168(3):673-85. PubMed ID: 23004938
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Evodiamine exerts anti-tumor effects against hepatocellular carcinoma through inhibiting β-catenin-mediated angiogenesis.
    Shi L; Yang F; Luo F; Liu Y; Zhang F; Zou M; Liu Q
    Tumour Biol; 2016 Sep; 37(9):12791-12803. PubMed ID: 27449032
    [TBL] [Abstract][Full Text] [Related]  

  • 15. ENMD-1198, a novel tubulin-binding agent reduces HIF-1alpha and STAT3 activity in human hepatocellular carcinoma(HCC) cells, and inhibits growth and vascularization in vivo.
    Moser C; Lang SA; Mori A; Hellerbrand C; Schlitt HJ; Geissler EK; Fogler WE; Stoeltzing O
    BMC Cancer; 2008 Jul; 8():206. PubMed ID: 18651980
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Discovery of novel quinazolines as potential anti-tubulin agents occupying three zones of colchicine domain.
    Li W; Yin Y; Shuai W; Xu F; Yao H; Liu J; Cheng K; Xu J; Zhu Z; Xu S
    Bioorg Chem; 2019 Mar; 83():380-390. PubMed ID: 30408650
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Aloperine induces apoptosis and G2/M cell cycle arrest in hepatocellular carcinoma cells through the PI3K/Akt signaling pathway.
    Liu JS; Huo CY; Cao HH; Fan CL; Hu JY; Deng LJ; Lu ZB; Yang HY; Yu LZ; Mo ZX; Yu ZL
    Phytomedicine; 2019 Aug; 61():152843. PubMed ID: 31039533
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The Design, Synthesis, and Biological Activities of Pyrrole-Based Carboxamides: The Novel Tubulin Inhibitors Targeting the Colchicine-Binding Site.
    Boichuk S; Galembikova A; Syuzov K; Dunaev P; Bikinieva F; Aukhadieva A; Zykova S; Igidov N; Gankova K; Novikova M; Kopnin P
    Molecules; 2021 Sep; 26(19):. PubMed ID: 34641324
    [TBL] [Abstract][Full Text] [Related]  

  • 19. C118P exerted potent anti-tumor effects against melanoma with induction of G2/M arrest via inhibiting the expression of BUB1B.
    Ren K; Zhou M; Li L; Wang C; Yuan S; Li H
    J Dermatol Sci; 2022 Nov; 108(2):58-67. PubMed ID: 36424293
    [TBL] [Abstract][Full Text] [Related]  

  • 20. CKD-516 displays vascular disrupting properties and enhances anti-tumor activity in combination with chemotherapy in a murine tumor model.
    Moon CH; Lee SJ; Lee HY; Dung le TK; Cho WJ; Cha H; Park JW; Min YJ
    Invest New Drugs; 2014 Jun; 32(3):400-11. PubMed ID: 24202729
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.