These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

165 related articles for article (PubMed ID: 34083621)

  • 1. Generation of tetracycline-controllable CYP3A4-expressing Caco-2 cells by the piggyBac transposon system.
    Ichikawa M; Akamine H; Murata M; Ito S; Takayama K; Mizuguchi H
    Sci Rep; 2021 Jun; 11(1):11670. PubMed ID: 34083621
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Generation of Caco-2 cells stably expressing CYP3A4·POR·UGT1A1 and CYP3A4·POR·UGT1A1*6 using a PITCh system.
    Negoro R; Yamada N; Watanabe K; Kono Y; Fujita T
    Arch Toxicol; 2022 Feb; 96(2):499-510. PubMed ID: 34654938
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Development of Caco-2 cells expressing four CYPs via a mammalian artificial chromosome.
    Ohta Y; Kazuki K; Abe S; Oshimura M; Kobayashi K; Kazuki Y
    BMC Biotechnol; 2020 Aug; 20(1):44. PubMed ID: 32819341
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A doxycycline-inducible CYP3A4-Caco-2 cell line as a model for evaluating safety of aflatoxin B1 in the human intestine.
    Bai L; Tachibana K; Murata M; Inoue T; Mizuguchi H; Maeda S; Ikemura K; Okuda M; Kusakabe T; Kondoh M
    Toxicol Lett; 2022 Nov; 370():1-6. PubMed ID: 36100150
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Generation of Caco-2 cells with predictable metabolism by CYP3A4, UGT1A1 and CES using the PITCh system.
    Yamada N; Negoro R; Watanabe K; Fujita T
    Drug Metab Pharmacokinet; 2023 Jun; 50():100497. PubMed ID: 37037169
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Establishment and Characterization of Novel Human Intestinal In Vitro Models for Absorption and First-Pass Metabolism Studies.
    Przybylla R; Mullins CS; Krohn M; Oswald S; Linnebacher M
    Int J Mol Sci; 2022 Aug; 23(17):. PubMed ID: 36077251
    [TBL] [Abstract][Full Text] [Related]  

  • 7. 5-ALA treatment increases intracellular heme levels and enhances CYP3A4 activity in genome-edited Caco-2 cells.
    Watanabe K; Negoro R; Fujita T
    Biochem Biophys Res Commun; 2023 Jul; 664():94-99. PubMed ID: 37141642
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Creation of polarized cells coexpressing CYP3A4, NADPH cytochrome P450 reductase and MDR1/P-glycoprotein.
    Brimer C; Dalton JT; Zhu Z; Schuetz J; Yasuda K; Vanin E; Relling MV; Lu Y; Schuetz EG
    Pharm Res; 2000 Jul; 17(7):803-10. PubMed ID: 10990198
    [TBL] [Abstract][Full Text] [Related]  

  • 9. CYP3A4, CYP3A5, and MDR1 in human small and large intestinal cell lines suitable for drug transport studies.
    Engman HA; Lennernäs H; Taipalensuu J; Otter C; Leidvik B; Artursson P
    J Pharm Sci; 2001 Nov; 90(11):1736-51. PubMed ID: 11745731
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Involvement of promoter methylation in the regulation of Pregnane X receptor in colon cancer cells.
    Habano W; Gamo T; Terashima J; Sugai T; Otsuka K; Wakabayashi G; Ozawa S
    BMC Cancer; 2011 Feb; 11():81. PubMed ID: 21342487
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Generation of Human iPSC-Derived Intestinal Epithelial Cell Monolayers by CDX2 Transduction.
    Takayama K; Negoro R; Yamashita T; Kawai K; Ichikawa M; Mori T; Nakatsu N; Harada K; Ito S; Yamada H; Yamaura Y; Hirata K; Ishida S; Mizuguchi H
    Cell Mol Gastroenterol Hepatol; 2019; 8(3):513-526. PubMed ID: 31228606
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Development of Caco-2 cells co-expressing CYP3A4 and NADPH-cytochrome P450 reductase using a human artificial chromosome for the prediction of intestinal extraction ratio of CYP3A4 substrates.
    Takenaka T; Kazuki K; Harada N; Kuze J; Chiba M; Iwao T; Matsunaga T; Abe S; Oshimura M; Kazuki Y
    Drug Metab Pharmacokinet; 2017 Feb; 32(1):61-68. PubMed ID: 28139373
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Expression of enzymatically active CYP3A4 by Caco-2 cells grown on extracellular matrix-coated permeable supports in the presence of 1alpha,25-dihydroxyvitamin D3.
    Schmiedlin-Ren P; Thummel KE; Fisher JM; Paine MF; Lown KS; Watkins PB
    Mol Pharmacol; 1997 May; 51(5):741-54. PubMed ID: 9145912
    [TBL] [Abstract][Full Text] [Related]  

  • 14. CYP3A4-transfected Caco-2 cells as a tool for understanding biochemical absorption barriers: studies with sirolimus and midazolam.
    Cummins CL; Jacobsen W; Christians U; Benet LZ
    J Pharmacol Exp Ther; 2004 Jan; 308(1):143-55. PubMed ID: 14569063
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Transfected MDCK cell line with enhanced expression of CYP3A4 and P-glycoprotein as a model to study their role in drug transport and metabolism.
    Kwatra D; Budda B; Vadlapudi AD; Vadlapatla RK; Pal D; Mitra AK
    Mol Pharm; 2012 Jul; 9(7):1877-86. PubMed ID: 22676443
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Establishment of MDCKII cell monolayer with metabolic activity by CYP3A4 transduced with recombinant adenovirus.
    Kataoka M; Terashima Y; Mizuno K; Masaoka Y; Sakuma S; Yokoi T; Yamashita S
    Drug Metab Pharmacokinet; 2013; 28(2):125-31. PubMed ID: 22892444
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Transport and metabolic characterization of Caco-2 cells expressing CYP3A4 and CYP3A4 plus oxidoreductase.
    Hu M; Li Y; Davitt CM; Huang SM; Thummel K; Penman BW; Crespi CL
    Pharm Res; 1999 Sep; 16(9):1352-9. PubMed ID: 10496649
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Baicalin pharmacokinetic profile of absorption process using novel in-vitro model: cytochrome P450 3A4-induced Caco-2 cell monolayers combined with rat intestinal rinse fluids.
    Morisaki T; Hou XL; Takahashi K; Takahashi K
    J Pharm Pharmacol; 2013 Oct; 65(10):1526-35. PubMed ID: 24028620
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Transport and uptake of clausenamide enantiomers in CYP3A4-transfected Caco-2 cells: An insight into the efflux-metabolism alliance.
    Hua F; Shi MJ; Zhu XL; Li M; Wang HX; Yu XM; Li Y; Zhu CJ
    Biochem Pharmacol; 2015 Nov; 98(1):224-30. PubMed ID: 26301745
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Investigation of the coordinated functional activities of cytochrome P450 3A4 and P-glycoprotein in limiting the absorption of xenobiotics in Caco-2 cells.
    Tran CD; Timmins P; Conway BR; Irwin WJ
    J Pharm Sci; 2002 Jan; 91(1):117-28. PubMed ID: 11782903
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.