BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

331 related articles for article (PubMed ID: 34086738)

  • 1. Heparan sulfate proteoglycans in beta cells provide a critical link between endoplasmic reticulum stress, oxidative stress and type 2 diabetes.
    Dhounchak S; Popp SK; Brown DJ; Laybutt DR; Biden TJ; Bornstein SR; Parish CR; Simeonovic CJ
    PLoS One; 2021; 16(6):e0252607. PubMed ID: 34086738
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Islet heparan sulfate but not heparan sulfate proteoglycan core protein is lost during islet isolation and undergoes recovery post-islet transplantation.
    Choong FJ; Freeman C; Parish CR; Simeonovic CJ
    Am J Transplant; 2015 Nov; 15(11):2851-64. PubMed ID: 26104150
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Loss of intra-islet heparan sulfate is a highly sensitive marker of type 1 diabetes progression in humans.
    Simeonovic CJ; Popp SK; Starrs LM; Brown DJ; Ziolkowski AF; Ludwig B; Bornstein SR; Wilson JD; Pugliese A; Kay TWH; Thomas HE; Loudovaris T; Choong FJ; Freeman C; Parish CR
    PLoS One; 2018; 13(2):e0191360. PubMed ID: 29415062
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Heparanase degrades syndecan-1 and perlecan heparan sulfate: functional implications for tumor cell invasion.
    Reiland J; Sanderson RD; Waguespack M; Barker SA; Long R; Carson DD; Marchetti D
    J Biol Chem; 2004 Feb; 279(9):8047-55. PubMed ID: 14630925
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Heparan sulfate and heparanase play key roles in mouse β cell survival and autoimmune diabetes.
    Ziolkowski AF; Popp SK; Freeman C; Parish CR; Simeonovic CJ
    J Clin Invest; 2012 Jan; 122(1):132-41. PubMed ID: 22182841
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Alteration of endothelial proteoglycan and heparanase gene expression by high glucose, insulin and heparin.
    Han J; Hiebert LM
    Vascul Pharmacol; 2013; 59(3-4):112-8. PubMed ID: 23939434
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Endoplasmic reticulum stress contributes to beta cell apoptosis in type 2 diabetes.
    Laybutt DR; Preston AM; Akerfeldt MC; Kench JG; Busch AK; Biankin AV; Biden TJ
    Diabetologia; 2007 Apr; 50(4):752-63. PubMed ID: 17268797
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Heparan sulfate proteoglycans including syndecan-3 modulate BMP activity during limb cartilage differentiation.
    Fisher MC; Li Y; Seghatoleslami MR; Dealy CN; Kosher RA
    Matrix Biol; 2006 Jan; 25(1):27-39. PubMed ID: 16226436
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Combinatorial roles of heparan sulfate proteoglycans and heparan sulfates in Caenorhabditis elegans neural development.
    Kinnunen TK
    PLoS One; 2014; 9(7):e102919. PubMed ID: 25054285
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Dipeptidyl peptidase-4 inhibitor, vildagliptin, inhibits pancreatic beta cell apoptosis in association with its effects suppressing endoplasmic reticulum stress in db/db mice.
    Wu YJ; Guo X; Li CJ; Li DQ; Zhang J; Yang Y; Kong Y; Guo H; Liu DM; Chen LM
    Metabolism; 2015 Feb; 64(2):226-35. PubMed ID: 25195070
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Unexpected new roles for heparanase in Type 1 diabetes and immune gene regulation.
    Parish CR; Freeman C; Ziolkowski AF; He YQ; Sutcliffe EL; Zafar A; Rao S; Simeonovic CJ
    Matrix Biol; 2013 Jun; 32(5):228-33. PubMed ID: 23499527
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Overall sulfation of heparan sulfate from pancreatic islet β-TC3 cells increases maximal fibril formation but does not determine binding to the amyloidogenic peptide islet amyloid polypeptide.
    Hull RL; Peters MJ; Perigo SP; Chan CK; Wight TN; Kinsella MG
    J Biol Chem; 2012 Oct; 287(44):37154-64. PubMed ID: 22936797
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Heparanase and autoimmune diabetes.
    Simeonovic CJ; Ziolkowski AF; Wu Z; Choong FJ; Freeman C; Parish CR
    Front Immunol; 2013 Dec; 4():471. PubMed ID: 24421779
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Acute UV irradiation increases heparan sulfate proteoglycan levels in human skin.
    Jung JY; Oh JH; Kim YK; Shin MH; Lee D; Chung JH
    J Korean Med Sci; 2012 Mar; 27(3):300-6. PubMed ID: 22379342
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inhibition of deoxyhypusine synthase enhances islet {beta} cell function and survival in the setting of endoplasmic reticulum stress and type 2 diabetes.
    Robbins RD; Tersey SA; Ogihara T; Gupta D; Farb TB; Ficorilli J; Bokvist K; Maier B; Mirmira RG
    J Biol Chem; 2010 Dec; 285(51):39943-52. PubMed ID: 20956533
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Transgenic or tumor-induced expression of heparanase upregulates sulfation of heparan sulfate.
    Escobar Galvis ML; Jia J; Zhang X; Jastrebova N; Spillmann D; Gottfridsson E; van Kuppevelt TH; Zcharia E; Vlodavsky I; Lindahl U; Li JP
    Nat Chem Biol; 2007 Dec; 3(12):773-8. PubMed ID: 17952066
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The Orphan Nuclear Receptor NR4A1 Protects Pancreatic β-Cells from Endoplasmic Reticulum (ER) Stress-mediated Apoptosis.
    Yu C; Cui S; Zong C; Gao W; Xu T; Gao P; Chen J; Qin D; Guan Q; Liu Y; Fu Y; Li X; Wang X
    J Biol Chem; 2015 Aug; 290(34):20687-20699. PubMed ID: 26157144
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Endoplasmic reticulum stress contributes to NMDA-induced pancreatic β-cell dysfunction in a CHOP-dependent manner.
    Huang XT; Liu W; Zhou Y; Sun M; Sun CC; Zhang CY; Tang SY
    Life Sci; 2019 Sep; 232():116612. PubMed ID: 31260687
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Heparan sulfate proteoglycans are receptors for the cell-surface trafficking and biological activity of transglutaminase-2.
    Scarpellini A; Germack R; Lortat-Jacob H; Muramatsu T; Billett E; Johnson T; Verderio EA
    J Biol Chem; 2009 Jul; 284(27):18411-23. PubMed ID: 19398782
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Roles of heparan sulfate sulfation in dentinogenesis.
    Hayano S; Kurosaka H; Yanagita T; Kalus I; Milz F; Ishihara Y; Islam MN; Kawanabe N; Saito M; Kamioka H; Adachi T; Dierks T; Yamashiro T
    J Biol Chem; 2012 Apr; 287(15):12217-29. PubMed ID: 22351753
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.