BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

454 related articles for article (PubMed ID: 34087454)

  • 21. Blockade of IDO-kynurenine-AhR metabolic circuitry abrogates IFN-γ-induced immunologic dormancy of tumor-repopulating cells.
    Liu Y; Liang X; Yin X; Lv J; Tang K; Ma J; Ji T; Zhang H; Dong W; Jin X; Chen D; Li Y; Zhang S; Xie HQ; Zhao B; Zhao T; Lu J; Hu ZW; Cao X; Qin FX; Huang B
    Nat Commun; 2017 May; 8():15207. PubMed ID: 28488695
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Associations of microbial and indoleamine-2,3-dioxygenase-derived tryptophan metabolites with immune activation in healthy adults.
    Riazati N; Kable ME; Newman JW; Adkins Y; Freytag T; Jiang X; Stephensen CB
    Front Immunol; 2022; 13():917966. PubMed ID: 36248784
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Hepatic stellate cells increase the immunosuppressive function of natural Foxp3+ regulatory T cells via IDO-induced AhR activation.
    Kumar S; Wang J; Thomson AW; Gandhi CR
    J Leukoc Biol; 2017 Feb; 101(2):429-438. PubMed ID: 27581538
    [TBL] [Abstract][Full Text] [Related]  

  • 24. The mannose receptor negatively modulates the Toll-like receptor 4-aryl hydrocarbon receptor-indoleamine 2,3-dioxygenase axis in dendritic cells affecting T helper cell polarization.
    Salazar F; Hall L; Negm OH; Awuah D; Tighe PJ; Shakib F; Ghaemmaghami AM
    J Allergy Clin Immunol; 2016 Jun; 137(6):1841-1851.e2. PubMed ID: 26703454
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Reshaping the tumor microenvironment with oncolytic viruses, positive regulation of the immune synapse, and blockade of the immunosuppressive oncometabolic circuitry.
    Nguyen TT; Shin DH; Sohoni S; Singh SK; Rivera-Molina Y; Jiang H; Fan X; Gumin J; Lang FF; Alvarez-Breckenridge C; Godoy-Vitorino F; Zhu L; Zheng WJ; Zhai L; Ladomersky E; Lauing KL; Alonso MM; Wainwright DA; Gomez-Manzano C; Fueyo J
    J Immunother Cancer; 2022 Jul; 10(7):. PubMed ID: 35902132
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Tryptophan metabolite activation of the aryl hydrocarbon receptor regulates IL-10 receptor expression on intestinal epithelia.
    Lanis JM; Alexeev EE; Curtis VF; Kitzenberg DA; Kao DJ; Battista KD; Gerich ME; Glover LE; Kominsky DJ; Colgan SP
    Mucosal Immunol; 2017 Sep; 10(5):1133-1144. PubMed ID: 28098246
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Aryl hydrocarbon receptor signaling mediates expression of indoleamine 2,3-dioxygenase.
    Vogel CF; Goth SR; Dong B; Pessah IN; Matsumura F
    Biochem Biophys Res Commun; 2008 Oct; 375(3):331-5. PubMed ID: 18694728
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Kynurenine, a Tryptophan Metabolite That Increases with Age, Induces Muscle Atrophy and Lipid Peroxidation.
    Kaiser H; Yu K; Pandya C; Mendhe B; Isales CM; McGee-Lawrence ME; Johnson M; Fulzele S; Hamrick MW
    Oxid Med Cell Longev; 2019; 2019():9894238. PubMed ID: 31737181
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Norisoboldine, a natural AhR agonist, promotes Treg differentiation and attenuates colitis via targeting glycolysis and subsequent NAD
    Lv Q; Wang K; Qiao S; Yang L; Xin Y; Dai Y; Wei Z
    Cell Death Dis; 2018 Feb; 9(3):258. PubMed ID: 29449535
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Hypothesis: Emerging Roles for Aryl Hydrocarbon Receptor in Orchestrating CoV-2-Related Inflammation.
    Guarnieri T
    Cells; 2022 Feb; 11(4):. PubMed ID: 35203299
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Constitutive IDO expression in human cancer is sustained by an autocrine signaling loop involving IL-6, STAT3 and the AHR.
    Litzenburger UM; Opitz CA; Sahm F; Rauschenbach KJ; Trump S; Winter M; Ott M; Ochs K; Lutz C; Liu X; Anastasov N; Lehmann I; Höfer T; von Deimling A; Wick W; Platten M
    Oncotarget; 2014 Feb; 5(4):1038-51. PubMed ID: 24657910
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Stemness and immune evasion conferred by the TDO2-AHR pathway are associated with liver metastasis of colon cancer.
    Miyazaki T; Chung S; Sakai H; Ohata H; Obata Y; Shiokawa D; Mizoguchi Y; Kubo T; Ichikawa H; Taniguchi H; Aoki K; Soga T; Nakagama H; Okamoto K
    Cancer Sci; 2022 Jan; 113(1):170-181. PubMed ID: 34714577
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Dubosiella newyorkensis modulates immune tolerance in colitis via the L-lysine-activated AhR-IDO1-Kyn pathway.
    Zhang Y; Tu S; Ji X; Wu J; Meng J; Gao J; Shao X; Shi S; Wang G; Qiu J; Zhang Z; Hua C; Zhang Z; Chen S; Zhang L; Zhu SJ
    Nat Commun; 2024 Feb; 15(1):1333. PubMed ID: 38351003
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Tryptophan metabolism induced by TDO2 promotes prostatic cancer chemotherapy resistance in a AhR/c-Myc dependent manner.
    Li F; Zhao Z; Zhang Z; Zhang Y; Guan W
    BMC Cancer; 2021 Oct; 21(1):1112. PubMed ID: 34657603
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Inhibition of indoleamine 2,3-dioxygenase 1 expression alters immune response in colon tumor microenvironment in mice.
    Takamatsu M; Hirata A; Ohtaki H; Hoshi M; Ando T; Ito H; Hatano Y; Tomita H; Kuno T; Saito K; Seishima M; Hara A
    Cancer Sci; 2015 Aug; 106(8):1008-15. PubMed ID: 26033215
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Indoleamine 2, 3-Dioxygenase Promotes Aryl Hydrocarbon Receptor-Dependent Differentiation Of Regulatory B Cells in Lung Cancer.
    Tousif S; Wang Y; Jackson J; Hough KP; Strenkowski JG; Athar M; Thannickal VJ; McCusker RH; Ponnazhagan S; Deshane JS
    Front Immunol; 2021; 12():747780. PubMed ID: 34867973
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Targeting the aryl hydrocarbon receptor (AhR) with BAY 2416964: a selective small molecule inhibitor for cancer immunotherapy.
    Kober C; Roewe J; Schmees N; Roese L; Roehn U; Bader B; Stoeckigt D; Prinz F; Gorjánácz M; Roider HG; Olesch C; Leder G; Irlbacher H; Lesche R; Lefranc J; Oezcan-Wahlbrink M; Batra AS; Elmadany N; Carretero R; Sahm K; Oezen I; Cichon F; Baumann D; Sadik A; Opitz CA; Weinmann H; Hartung IV; Kreft B; Offringa R; Platten M; Gutcher I
    J Immunother Cancer; 2023 Nov; 11(11):. PubMed ID: 37963637
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Involvement of Aryl Hydrocarbon Receptor in L-Kynurenine-Mediated Parathyroid Hormone-Related Peptide Expression.
    Duan Z; Lu J
    Horm Cancer; 2019 Jun; 10(2-3):89-96. PubMed ID: 30689168
    [TBL] [Abstract][Full Text] [Related]  

  • 39. MondoA-Thioredoxin-Interacting Protein Axis Maintains Regulatory T-Cell Identity and Function in Colorectal Cancer Microenvironment.
    Lu Y; Li Y; Liu Q; Tian N; Du P; Zhu F; Han Y; Liu X; Liu X; Peng X; Wang X; Wu Y; Tong L; Li Y; Zhu Y; Wu L; Zhang P; Xu Y; Chen H; Li B; Tong X
    Gastroenterology; 2021 Aug; 161(2):575-591.e16. PubMed ID: 33901495
    [TBL] [Abstract][Full Text] [Related]  

  • 40. IDO1 and Kynurenine Pathway Metabolites Activate PI3K-Akt Signaling in the Neoplastic Colon Epithelium to Promote Cancer Cell Proliferation and Inhibit Apoptosis.
    Bishnupuri KS; Alvarado DM; Khouri AN; Shabsovich M; Chen B; Dieckgraefe BK; Ciorba MA
    Cancer Res; 2019 Mar; 79(6):1138-1150. PubMed ID: 30679179
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 23.