125 related articles for article (PubMed ID: 34089986)
1. Multiple machine learning models combined with virtual screening and molecular docking to identify selective human ALDH1A1 inhibitors.
Narendra G; Raju B; Verma H; Sapra B; Silakari O
J Mol Graph Model; 2021 Sep; 107():107950. PubMed ID: 34089986
[TBL] [Abstract][Full Text] [Related]
2. 3D-QSAR and scaffold hopping based designing of benzo[d]ox-azol-2(3H)-one and 2-oxazolo[4,5-b]pyridin-2(3H)-one derivatives as selective aldehyde dehydrogenase 1A1 inhibitors: Synthesis and biological evaluation.
Verma H; Narendra G; Raju B; Kumar M; Jain SK; Tung GK; Singh PK; Silakari O
Arch Pharm (Weinheim); 2022 Sep; 355(9):e2200108. PubMed ID: 35618489
[TBL] [Abstract][Full Text] [Related]
3. Raloxifene and bazedoxifene as selective ALDH1A1 inhibitors to ameliorate cyclophosphamide resistance: A drug repurposing approach.
Narendra G; Raju B; Verma H; Kumar M; Jain SK; Tung GK; Thakur S; Kaur R; Kaur S; Sapra B; Singh PK; Silakari O
Int J Biol Macromol; 2023 Jul; 242(Pt 1):124749. PubMed ID: 37160174
[TBL] [Abstract][Full Text] [Related]
4. Discovery and development of selective aldehyde dehydrogenase 1A1 (ALDH1A1) inhibitors.
Li B; Yang K; Liang D; Jiang C; Ma Z
Eur J Med Chem; 2021 Jan; 209():112940. PubMed ID: 33328099
[TBL] [Abstract][Full Text] [Related]
5. Discovery of NCT-501, a Potent and Selective Theophylline-Based Inhibitor of Aldehyde Dehydrogenase 1A1 (ALDH1A1).
Yang SM; Yasgar A; Miller B; Lal-Nag M; Brimacombe K; Hu X; Sun H; Wang A; Xu X; Nguyen K; Oppermann U; Ferrer M; Vasiliou V; Simeonov A; Jadhav A; Maloney DJ
J Med Chem; 2015 Aug; 58(15):5967-78. PubMed ID: 26207746
[TBL] [Abstract][Full Text] [Related]
6. Novel Disulfiram Derivatives as ALDH1a1-Selective Inhibitors.
Omran Z
Molecules; 2022 Jan; 27(2):. PubMed ID: 35056791
[TBL] [Abstract][Full Text] [Related]
7. Multiple machine learning, molecular docking, and ADMET screening approach for identification of selective inhibitors of CYP1B1.
Raju B; Verma H; Narendra G; Sapra B; Silakari O
J Biomol Struct Dyn; 2022 Oct; 40(17):7975-7990. PubMed ID: 33769194
[TBL] [Abstract][Full Text] [Related]
8. Discovery of Orally Bioavailable, Quinoline-Based Aldehyde Dehydrogenase 1A1 (ALDH1A1) Inhibitors with Potent Cellular Activity.
Yang SM; Martinez NJ; Yasgar A; Danchik C; Johansson C; Wang Y; Baljinnyam B; Wang AQ; Xu X; Shah P; Cheff D; Wang XS; Roth J; Lal-Nag M; Dunford JE; Oppermann U; Vasiliou V; Simeonov A; Jadhav A; Maloney DJ
J Med Chem; 2018 Jun; 61(11):4883-4903. PubMed ID: 29767973
[TBL] [Abstract][Full Text] [Related]
9. Aldehyde dehydrogenase 1B1 (ALDH1B1) is a potential biomarker for human colon cancer.
Chen Y; Orlicky DJ; Matsumoto A; Singh S; Thompson DC; Vasiliou V
Biochem Biophys Res Commun; 2011 Feb; 405(2):173-9. PubMed ID: 21216231
[TBL] [Abstract][Full Text] [Related]
10. Design, synthesis characterization and biological evaluation of novel multi-isoform ALDH inhibitors as potential anticancer agents.
Dinavahi SS; Gowda R; Bazewicz CG; Battu MB; Lin JM; Chitren RJ; Pandey MK; Amin S; Robertson GP; Gowda K
Eur J Med Chem; 2020 Feb; 187():111962. PubMed ID: 31887569
[TBL] [Abstract][Full Text] [Related]
11. Development of new disulfiram analogues as ALDH1a1-selective inhibitors.
Omran Z
Bioorg Med Chem Lett; 2021 May; 40():127958. PubMed ID: 33744437
[TBL] [Abstract][Full Text] [Related]
12. Dual disruption of aldehyde dehydrogenases 1 and 3 promotes functional changes in the glutathione redox system and enhances chemosensitivity in nonsmall cell lung cancer.
Rebollido-Rios R; Venton G; Sánchez-Redondo S; Iglesias I Felip C; Fournet G; González E; Romero Fernández W; Borroto Escuela DO; Di Stefano B; Penarroche-Díaz R; Martin G; Ceylan I; Costello R; Perez-Alea M
Oncogene; 2020 Mar; 39(13):2756-2771. PubMed ID: 32015486
[TBL] [Abstract][Full Text] [Related]
13. Lower RNA expression of ALDH1A1 distinguishes the favorable risk group in acute myeloid leukemia.
Dancik GM; Voutsas IF; Vlahopoulos S
Mol Biol Rep; 2022 Apr; 49(4):3321-3331. PubMed ID: 35028852
[TBL] [Abstract][Full Text] [Related]
14. Omeprazole as a potent activator of human cytosolic aldehyde dehydrogenase ALDH1A1.
Calleja LF; Belmont-Díaz JA; Medina-Contreras O; Quezada H; Yoval-Sánchez B; Campos-García J; Rodríguez-Zavala JS
Biochim Biophys Acta Gen Subj; 2020 Jan; 1864(1):129451. PubMed ID: 31678145
[TBL] [Abstract][Full Text] [Related]
15. Scaffold hopping based designing of selective ALDH1A1 inhibitors to overcome cyclophosphamide resistance: synthesis and biological evaluation.
Narendra G; Raju B; Verma H; Kumar M; Jain SK; Tung GK; Thakur S; Kaur R; Kaur S; Sapra B; Silakari O
RSC Med Chem; 2024 Jan; 15(1):309-321. PubMed ID: 38283216
[TBL] [Abstract][Full Text] [Related]
16. Inhibitors of aldehyde dehydrogenases of the 1A subfamily as putative anticancer agents: Kinetic characterization and effect on human cancer cells.
Jiménez R; Pequerul R; Amor A; Lorenzo J; Metwally K; Avilés FX; Parés X; Farrés J
Chem Biol Interact; 2019 Jun; 306():123-130. PubMed ID: 30958995
[TBL] [Abstract][Full Text] [Related]
17. Design, synthesis of 1,3-dimethylpyrimidine-2,4-diones as potent and selective aldehyde dehydrogenase 1A1 (ALDH1A1) inhibitors with glucose consumption improving activity.
Ma Z; Jiang L; Li G; Liang D; Li L; Liu L; Jiang C
Bioorg Chem; 2020 Aug; 101():103971. PubMed ID: 32480173
[TBL] [Abstract][Full Text] [Related]
18. Discovery of benzimidazole derivatives as potent and selective aldehyde dehydrogenase 1A1 (ALDH1A1) inhibitors with glucose consumption improving activity.
Ma Z; Jiang L; Li B; Liang D; Feng Y; Liu L; Jiang C
Bioorg Med Chem; 2021 Sep; 46():116352. PubMed ID: 34403955
[TBL] [Abstract][Full Text] [Related]
19. Development of a high-throughput in vitro assay to identify selective inhibitors for human ALDH1A1.
Morgan CA; Hurley TD
Chem Biol Interact; 2015 Jun; 234():29-37. PubMed ID: 25450233
[TBL] [Abstract][Full Text] [Related]
20. Characterization of two distinct structural classes of selective aldehyde dehydrogenase 1A1 inhibitors.
Morgan CA; Hurley TD
J Med Chem; 2015 Feb; 58(4):1964-75. PubMed ID: 25634381
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
