These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

258 related articles for article (PubMed ID: 34099494)

  • 1. A Wnt-Independent LGR4-EGFR Signaling Axis in Cancer Metastasis.
    Yue F; Jiang W; Ku AT; Young AIJ; Zhang W; Souto EP; Gao Y; Yu Z; Wang Y; Creighton CJ; Nagi C; Wang T; Hilsenbeck SG; Feng XH; Huang S; Coarfa C; Zhang XH; Liu Q; Lin X; Li Y
    Cancer Res; 2021 Sep; 81(17):4441-4454. PubMed ID: 34099494
    [TBL] [Abstract][Full Text] [Related]  

  • 2. LGR4 modulates breast cancer initiation, metastasis, and cancer stem cells.
    Yue Z; Yuan Z; Zeng L; Wang Y; Lai L; Li J; Sun P; Xue X; Qi J; Yang Z; Zheng Y; Fang Y; Li D; Siwko S; Li Y; Luo J; Liu M
    FASEB J; 2018 May; 32(5):2422-2437. PubMed ID: 29269400
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Differential activities and mechanisms of the four R-spondins in potentiating Wnt/β-catenin signaling.
    Park S; Cui J; Yu W; Wu L; Carmon KS; Liu QJ
    J Biol Chem; 2018 Jun; 293(25):9759-9769. PubMed ID: 29752411
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Aberrantly expressed LGR4 empowers Wnt signaling in multiple myeloma by hijacking osteoblast-derived R-spondins.
    van Andel H; Ren Z; Koopmans I; Joosten SP; Kocemba KA; de Lau W; Kersten MJ; de Bruin AM; Guikema JE; Clevers H; Spaargaren M; Pals ST
    Proc Natl Acad Sci U S A; 2017 Jan; 114(2):376-381. PubMed ID: 28028233
    [TBL] [Abstract][Full Text] [Related]  

  • 5. R-spondin 2-LGR4 system regulates growth, migration and invasion, epithelial-mesenchymal transition and stem-like properties of tongue squamous cell carcinoma via Wnt/β-catenin signaling.
    Zhang L; Song Y; Ling Z; Li Y; Ren X; Yang J; Wang Z; Xia J; Zhang W; Cheng B
    EBioMedicine; 2019 Jun; 44():275-288. PubMed ID: 31097406
    [TBL] [Abstract][Full Text] [Related]  

  • 6. RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.
    Carmon KS; Gong X; Yi J; Thomas A; Liu Q
    Proc Natl Acad Sci U S A; 2014 Apr; 111(13):E1221-9. PubMed ID: 24639526
    [TBL] [Abstract][Full Text] [Related]  

  • 7. LGR4: Not Just for Wnt Anymore?
    Stevens PD; Williams BO
    Cancer Res; 2021 Sep; 81(17):4397-4398. PubMed ID: 34470783
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Effect of LGR4/EGFR signaling on cell growth and cancer stem cell-like characteristics in liver cancer.
    Liu Y; Zhang Y; Chen S; Zhong X; Liu Q
    Cytokine; 2023 May; 165():156185. PubMed ID: 37001327
    [TBL] [Abstract][Full Text] [Related]  

  • 9. R-Spondin potentiates Wnt/β-catenin signaling through orphan receptors LGR4 and LGR5.
    Ruffner H; Sprunger J; Charlat O; Leighton-Davies J; Grosshans B; Salathe A; Zietzling S; Beck V; Therier M; Isken A; Xie Y; Zhang Y; Hao H; Shi X; Liu D; Song Q; Clay I; Hintzen G; Tchorz J; Bouchez LC; Michaud G; Finan P; Myer VE; Bouwmeester T; Porter J; Hild M; Bassilana F; Parker CN; Cong F
    PLoS One; 2012; 7(7):e40976. PubMed ID: 22815884
    [TBL] [Abstract][Full Text] [Related]  

  • 10. RSPO2 and RANKL signal through LGR4 to regulate osteoclastic premetastatic niche formation and bone metastasis.
    Yue Z; Niu X; Yuan Z; Qin Q; Jiang W; He L; Gao J; Ding Y; Liu Y; Xu Z; Li Z; Yang Z; Li R; Xue X; Gao Y; Yue F; Zhang XH; Hu G; Wang Y; Li Y; Chen G; Siwko S; Gartland A; Wang N; Xiao J; Liu M; Luo J
    J Clin Invest; 2022 Jan; 132(2):. PubMed ID: 34847079
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Lgr4 gene regulates corpus luteum maturation through modulation of the WNT-mediated EGFR-ERK signaling pathway.
    Pan H; Cui H; Liu S; Qian Y; Wu H; Li L; Guan Y; Guan X; Zhang L; Fan HY; Ma Y; Li R; Liu M; Li D
    Endocrinology; 2014 Sep; 155(9):3624-37. PubMed ID: 24877628
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Regulation of the follistatin gene by RSPO-LGR4 signaling via activation of the WNT/β-catenin pathway in skeletal myogenesis.
    Han XH; Jin YR; Tan L; Kosciuk T; Lee JS; Yoon JK
    Mol Cell Biol; 2014 Feb; 34(4):752-64. PubMed ID: 24344199
    [TBL] [Abstract][Full Text] [Related]  

  • 13. LGR4 acts as a key receptor for R-spondin 2 to promote osteogenesis through Wnt signaling pathway.
    Zhu C; Zheng XF; Yang YH; Li B; Wang YR; Jiang SD; Jiang LS
    Cell Signal; 2016 Aug; 28(8):989-1000. PubMed ID: 27140682
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Leucine-rich repeat-containing G protein-coupled receptor 4 (Lgr4) is necessary for prostate cancer metastasis via epithelial-mesenchymal transition.
    Luo W; Tan P; Rodriguez M; He L; Tan K; Zeng L; Siwko S; Liu M
    J Biol Chem; 2017 Sep; 292(37):15525-15537. PubMed ID: 28768769
    [TBL] [Abstract][Full Text] [Related]  

  • 15. MiR-218 impedes IL-6-induced prostate cancer cell proliferation and invasion via suppression of LGR4 expression.
    Li F; Gu C; Tian F; Jia Z; Meng Z; Ding Y; Yang J
    Oncol Rep; 2016 May; 35(5):2859-65. PubMed ID: 26986507
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Unlike LGR4, LGR5 potentiates Wnt-β-catenin signaling without sequestering E3 ligases.
    Park S; Wu L; Tu J; Yu W; Toh Y; Carmon KS; Liu QJ
    Sci Signal; 2020 Dec; 13(660):. PubMed ID: 33262293
    [No Abstract]   [Full Text] [Related]  

  • 17. Interaction with both ZNRF3 and LGR4 is required for the signalling activity of R-spondin.
    Xie Y; Zamponi R; Charlat O; Ramones M; Swalley S; Jiang X; Rivera D; Tschantz W; Lu B; Quinn L; Dimitri C; Parker J; Jeffery D; Wilcox SK; Watrobka M; LeMotte P; Granda B; Porter JA; Myer VE; Loew A; Cong F
    EMBO Rep; 2013 Dec; 14(12):1120-6. PubMed ID: 24165923
    [TBL] [Abstract][Full Text] [Related]  

  • 18. R-spondin 3/LGR4 (Leucine-Rich Repeat-Containing G Protein-Coupled Receptor 4) Axis Is a Novel Inflammatory and Neurite Outgrowth Signaling System in the Ischemic Brain in Mice.
    Shimamura M; Hayashi H; Ju N; Yoshida S; Baba S; Sasaki T; Mochizuki H; Morishita R; Nakagami H
    Stroke; 2023 Jun; 54(6):1606-1615. PubMed ID: 37165865
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling.
    de Lau W; Barker N; Low TY; Koo BK; Li VS; Teunissen H; Kujala P; Haegebarth A; Peters PJ; van de Wetering M; Stange DE; van Es JE; Guardavaccaro D; Schasfoort RB; Mohri Y; Nishimori K; Mohammed S; Heck AJ; Clevers H
    Nature; 2011 Jul; 476(7360):293-7. PubMed ID: 21727895
    [TBL] [Abstract][Full Text] [Related]  

  • 20. R-spondins function as ligands of the orphan receptors LGR4 and LGR5 to regulate Wnt/beta-catenin signaling.
    Carmon KS; Gong X; Lin Q; Thomas A; Liu Q
    Proc Natl Acad Sci U S A; 2011 Jul; 108(28):11452-7. PubMed ID: 21693646
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.