BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

170 related articles for article (PubMed ID: 34102377)

  • 1. Acyclic nucleoside phosphonates with 2-aminothiazole base as inhibitors of bacterial and mammalian adenylate cyclases.
    Břehová P; Chaloupecká E; Česnek M; Skácel J; Dračínský M; Tloušťová E; Mertlíková-Kaiserová H; Soto-Velasquez MP; Watts VJ; Janeba Z
    Eur J Med Chem; 2021 Oct; 222():113581. PubMed ID: 34102377
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Halogen-Dance-Based Synthesis of Phosphonomethoxyethyl (PME) Substituted 2-Aminothiazoles as Potent Inhibitors of Bacterial Adenylate Cyclases.
    Česnek M; Šafránek M; Dračínský M; Tloušťová E; Mertlíková-Kaiserová H; Hayes MP; Watts VJ; Janeba Z
    ChemMedChem; 2022 Jan; 17(1):e202100568. PubMed ID: 34636150
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Nucleobase Modified Adefovir (PMEA) Analogues as Potent and Selective Inhibitors of Adenylate Cyclases from Bordetella pertussis and Bacillus anthracis.
    Česnek M; Skácel J; Jansa P; Dračínský M; Šmídková M; Mertlíková-Kaiserová H; Soto-Velasquez MP; Watts VJ; Janeba Z
    ChemMedChem; 2018 Sep; 13(17):1779-1796. PubMed ID: 29968968
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis of α-Branched Acyclic Nucleoside Phosphonates as Potential Inhibitors of Bacterial Adenylate Cyclases.
    Frydrych J; Skácel J; Šmídková M; Mertlíková-Kaiserová H; Dračínský M; Gnanasekaran R; Lepšík M; Soto-Velasquez M; Watts VJ; Janeba Z
    ChemMedChem; 2018 Jan; 13(2):199-206. PubMed ID: 29235265
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Design and Synthesis of Fluorescent Acyclic Nucleoside Phosphonates as Potent Inhibitors of Bacterial Adenylate Cyclases.
    Břehová P; Šmídková M; Skácel J; Dračínský M; Mertlíková-Kaiserová H; Velasquez MP; Watts VJ; Janeba Z
    ChemMedChem; 2016 Nov; 11(22):2534-2546. PubMed ID: 27775243
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Bisamidate Prodrugs of 2-Substituted 9-[2-(Phosphonomethoxy)ethyl]adenine (PMEA, adefovir) as Selective Inhibitors of Adenylate Cyclase Toxin from Bordetella pertussis.
    Česnek M; Jansa P; Šmídková M; Mertlíková-Kaiserová H; Dračínský M; Brust TF; Pávek P; Trejtnar F; Watts VJ; Janeba Z
    ChemMedChem; 2015 Aug; 10(8):1351-64. PubMed ID: 26136378
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Discovery of a potent and selective human AC2 inhibitor based on 7-deazapurine analogues of adefovir.
    Kraina P; Česnek M; Tloušťová E; Mertlíková-Kaiserová H; Fulton CJ; Davidson EK; Smith BP; Watts VJ; Janeba Z
    Bioorg Med Chem; 2023 Nov; 95():117508. PubMed ID: 37931521
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Amidate prodrugs of 9-[2-(phosphonomethoxy)ethyl]adenine as inhibitors of adenylate cyclase toxin from Bordetella pertussis.
    Šmídková M; Dvoráková A; Tloust'ová E; Česnek M; Janeba Z; Mertlíková-Kaiserová H
    Antimicrob Agents Chemother; 2014; 58(2):664-71. PubMed ID: 24145524
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Towards selective inhibitors of adenylyl cyclase toxin from Bordetella pertussis.
    Seifert R; Dove S
    Trends Microbiol; 2012 Jul; 20(7):343-51. PubMed ID: 22578665
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inhibition of Bordetella pertussis and Bacillus anthracis adenylyl cyclases by polyadenylate and "P"-site agonists.
    Johnson RA; Shoshani I
    J Biol Chem; 1990 Nov; 265(31):19035-9. PubMed ID: 2121733
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Coordination Chemistry of Nucleotides and Antivirally Active Acyclic Nucleoside Phosphonates, including Mechanistic Considerations.
    Sigel A; Sigel H; Sigel RKO
    Molecules; 2022 Apr; 27(9):. PubMed ID: 35565975
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Xanthine-based acyclic nucleoside phosphonates with potent antiviral activity against varicella-zoster virus and human cytomegalovirus.
    Baszczyňski O; Kaiser MM; Česnek M; Břehová P; Jansa P; Procházková E; Dračínský M; Snoeck R; Andrei G; Janeba Z
    Antivir Chem Chemother; 2018; 26():2040206618813050. PubMed ID: 30497281
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Bis-halogen-anthraniloyl-substituted nucleoside 5'-triphosphates as potent and selective inhibitors of Bordetella pertussis adenylyl cyclase toxin.
    Geduhn J; Dove S; Shen Y; Tang WJ; König B; Seifert R
    J Pharmacol Exp Ther; 2011 Jan; 336(1):104-15. PubMed ID: 20962032
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inhibitors of receptor-mediated endocytosis block the entry of Bacillus anthracis adenylate cyclase toxin but not that of Bordetella pertussis adenylate cyclase toxin.
    Gordon VM; Leppla SH; Hewlett EL
    Infect Immun; 1988 May; 56(5):1066-9. PubMed ID: 2895741
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The adenylate cyclase toxins.
    Ahuja N; Kumar P; Bhatnagar R
    Crit Rev Microbiol; 2004; 30(3):187-96. PubMed ID: 15490970
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Bordetella pertussis adenylate cyclase toxin modulates innate and adaptive immune responses: distinct roles for acylation and enzymatic activity in immunomodulation and cell death.
    Boyd AP; Ross PJ; Conroy H; Mahon N; Lavelle EC; Mills KH
    J Immunol; 2005 Jul; 175(2):730-8. PubMed ID: 16002668
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Interactions of Bordetella pertussis adenylyl cyclase toxin CyaA with calmodulin mutants and calmodulin antagonists: comparison with membranous adenylyl cyclase I.
    Schuler D; Lübker C; Lushington GH; Tang WJ; Shen Y; Richter M; Seifert R
    Biochem Pharmacol; 2012 Apr; 83(7):839-848. PubMed ID: 22265637
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Relationships between the calmodulin-dependent adenylate cyclases produced by Bacillus anthracis and Bordetella pertussis.
    Robertson DL
    Biochem Biophys Res Commun; 1988 Dec; 157(3):1027-32. PubMed ID: 2905126
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Sulfide, sulfoxide and sulfone bridged acyclic nucleoside phosphonates as inhibitors of the Plasmodium falciparum and human 6-oxopurine phosphoribosyltransferases: Synthesis and evaluation.
    Klejch T; Keough DT; Chavchich M; Travis J; Skácel J; Pohl R; Janeba Z; Edstein MD; Avery VM; Guddat LW; Hocková D
    Eur J Med Chem; 2019 Dec; 183():111667. PubMed ID: 31536893
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Binding of 3'-anthraniloyl-2'-deoxy-ATP to calmodulin-activated adenylate cyclase from Bordetella pertussis and Bacillus anthracis.
    Sarfati RS; Kansal VK; Munier H; Glaser P; Gilles AM; Labruyère E; Mock M; Danchin A; Bârzu O
    J Biol Chem; 1990 Nov; 265(31):18902-6. PubMed ID: 2172237
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.