594 related articles for article (PubMed ID: 34103079)
1. CSF1R inhibition rescues tau pathology and neurodegeneration in an A/T/N model with combined AD pathologies, while preserving plaque associated microglia.
Lodder C; Scheyltjens I; Stancu IC; Botella Lucena P; Gutiérrez de Ravé M; Vanherle S; Vanmierlo T; Cremers N; Vanrusselt H; Brône B; Hanseeuw B; Octave JN; Bottelbergs A; Movahedi K; Dewachter I
Acta Neuropathol Commun; 2021 Jun; 9(1):108. PubMed ID: 34103079
[TBL] [Abstract][Full Text] [Related]
2. Microglia depletion rapidly and reversibly alters amyloid pathology by modification of plaque compaction and morphologies.
Casali BT; MacPherson KP; Reed-Geaghan EG; Landreth GE
Neurobiol Dis; 2020 Aug; 142():104956. PubMed ID: 32479996
[TBL] [Abstract][Full Text] [Related]
3. Dystrophic (senescent) rather than activated microglial cells are associated with tau pathology and likely precede neurodegeneration in Alzheimer's disease.
Streit WJ; Braak H; Xue QS; Bechmann I
Acta Neuropathol; 2009 Oct; 118(4):475-85. PubMed ID: 19513731
[TBL] [Abstract][Full Text] [Related]
4. Early long-term administration of the CSF1R inhibitor PLX3397 ablates microglia and reduces accumulation of intraneuronal amyloid, neuritic plaque deposition and pre-fibrillar oligomers in 5XFAD mouse model of Alzheimer's disease.
Sosna J; Philipp S; Albay R; Reyes-Ruiz JM; Baglietto-Vargas D; LaFerla FM; Glabe CG
Mol Neurodegener; 2018 Mar; 13(1):11. PubMed ID: 29490706
[TBL] [Abstract][Full Text] [Related]
5. Plaque associated microglia hyper-secrete extracellular vesicles and accelerate tau propagation in a humanized APP mouse model.
Clayton K; Delpech JC; Herron S; Iwahara N; Ericsson M; Saito T; Saido TC; Ikezu S; Ikezu T
Mol Neurodegener; 2021 Mar; 16(1):18. PubMed ID: 33752701
[TBL] [Abstract][Full Text] [Related]
6. Colony-stimulating factor 1 receptor inhibition prevents microglial plaque association and improves cognition in 3xTg-AD mice.
Dagher NN; Najafi AR; Kayala KM; Elmore MR; White TE; Medeiros R; West BL; Green KN
J Neuroinflammation; 2015 Aug; 12():139. PubMed ID: 26232154
[TBL] [Abstract][Full Text] [Related]
7. Pharmacological targeting of CSF1R inhibits microglial proliferation and prevents the progression of Alzheimer's-like pathology.
Olmos-Alonso A; Schetters ST; Sri S; Askew K; Mancuso R; Vargas-Caballero M; Holscher C; Perry VH; Gomez-Nicola D
Brain; 2016 Mar; 139(Pt 3):891-907. PubMed ID: 26747862
[TBL] [Abstract][Full Text] [Related]
8. Trem2 restrains the enhancement of tau accumulation and neurodegeneration by β-amyloid pathology.
Lee SH; Meilandt WJ; Xie L; Gandham VD; Ngu H; Barck KH; Rezzonico MG; Imperio J; Lalehzadeh G; Huntley MA; Stark KL; Foreman O; Carano RAD; Friedman BA; Sheng M; Easton A; Bohlen CJ; Hansen DV
Neuron; 2021 Apr; 109(8):1283-1301.e6. PubMed ID: 33675684
[TBL] [Abstract][Full Text] [Related]
9. Microglia-mediated T cell infiltration drives neurodegeneration in tauopathy.
Chen X; Firulyova M; Manis M; Herz J; Smirnov I; Aladyeva E; Wang C; Bao X; Finn MB; Hu H; Shchukina I; Kim MW; Yuede CM; Kipnis J; Artyomov MN; Ulrich JD; Holtzman DM
Nature; 2023 Mar; 615(7953):668-677. PubMed ID: 36890231
[TBL] [Abstract][Full Text] [Related]
10. The relationship between the morphological subtypes of microglia and Alzheimer's disease neuropathology.
Paasila PJ; Davies DS; Kril JJ; Goldsbury C; Sutherland GT
Brain Pathol; 2019 Nov; 29(6):726-740. PubMed ID: 30803086
[TBL] [Abstract][Full Text] [Related]
11. Progression of neurofibrillary changes and PHF-tau in end-stage Alzheimer's disease is different from plaque and cortical microglial pathology.
Thal DR; Arendt T; Waldmann G; Holzer M; Zedlick D; Rüb U; Schober R
Neurobiol Aging; 1998; 19(6):517-25. PubMed ID: 10192210
[TBL] [Abstract][Full Text] [Related]
12. Diabetic phenotype in mouse and humans reduces the number of microglia around β-amyloid plaques.
Natunen T; Martiskainen H; Marttinen M; Gabbouj S; Koivisto H; Kemppainen S; Kaipainen S; Takalo M; Svobodová H; Leppänen L; Kemiläinen B; Ryhänen S; Kuulasmaa T; Rahunen E; Juutinen S; Mäkinen P; Miettinen P; Rauramaa T; Pihlajamäki J; Haapasalo A; Leinonen V; Tanila H; Hiltunen M
Mol Neurodegener; 2020 Nov; 15(1):66. PubMed ID: 33168021
[TBL] [Abstract][Full Text] [Related]
13. Metformin attenuates plaque-associated tau pathology and reduces amyloid-β burden in APP/PS1 mice.
Chen Y; Zhao S; Fan Z; Li Z; Zhu Y; Shen T; Li K; Yan Y; Tian J; Liu Z; Zhang B
Alzheimers Res Ther; 2021 Feb; 13(1):40. PubMed ID: 33563332
[TBL] [Abstract][Full Text] [Related]
14. Increased tauopathy drives microglia-mediated clearance of beta-amyloid.
Chen W; Abud EA; Yeung ST; Lakatos A; Nassi T; Wang J; Blum D; Buée L; Poon WW; Blurton-Jones M
Acta Neuropathol Commun; 2016 Jun; 4(1):63. PubMed ID: 27339073
[TBL] [Abstract][Full Text] [Related]
15. Effects of CX3CR1 and Fractalkine Chemokines in Amyloid Beta Clearance and p-Tau Accumulation in Alzheimer's Disease (AD) Rodent Models: Is Fractalkine a Systemic Biomarker for AD?
Merino JJ; Muñetón-Gómez V; Alvárez MI; Toledano-Díaz A
Curr Alzheimer Res; 2016; 13(4):403-12. PubMed ID: 26567742
[TBL] [Abstract][Full Text] [Related]
16. Amyloid plaque and neurofibrillary tangle pathology in a regulatable mouse model of Alzheimer's disease.
Paulson JB; Ramsden M; Forster C; Sherman MA; McGowan E; Ashe KH
Am J Pathol; 2008 Sep; 173(3):762-72. PubMed ID: 18669616
[TBL] [Abstract][Full Text] [Related]
17. Microglial activation correlates in vivo with both tau and amyloid in Alzheimer's disease.
Dani M; Wood M; Mizoguchi R; Fan Z; Walker Z; Morgan R; Hinz R; Biju M; Kuruvilla T; Brooks DJ; Edison P
Brain; 2018 Sep; 141(9):2740-2754. PubMed ID: 30052812
[TBL] [Abstract][Full Text] [Related]
18. Imaging of peripheral benzodiazepine receptor expression as biomarkers of detrimental versus beneficial glial responses in mouse models of Alzheimer's and other CNS pathologies.
Ji B; Maeda J; Sawada M; Ono M; Okauchi T; Inaji M; Zhang MR; Suzuki K; Ando K; Staufenbiel M; Trojanowski JQ; Lee VM; Higuchi M; Suhara T
J Neurosci; 2008 Nov; 28(47):12255-67. PubMed ID: 19020019
[TBL] [Abstract][Full Text] [Related]
19. Aβ-induced acceleration of Alzheimer-related τ-pathology spreading and its association with prion protein.
Gomes LA; Hipp SA; Rijal Upadhaya A; Balakrishnan K; Ospitalieri S; Koper MJ; Largo-Barrientos P; Uytterhoeven V; Reichwald J; Rabe S; Vandenberghe R; von Arnim CAF; Tousseyn T; Feederle R; Giudici C; Willem M; Staufenbiel M; Thal DR
Acta Neuropathol; 2019 Dec; 138(6):913-941. PubMed ID: 31414210
[TBL] [Abstract][Full Text] [Related]
20. CB2 receptor deficiency increases amyloid pathology and alters tau processing in a transgenic mouse model of Alzheimer's disease.
Koppel J; Vingtdeux V; Marambaud P; d'Abramo C; Jimenez H; Stauber M; Friedman R; Davies P
Mol Med; 2014 Mar; 20(1):29-36. PubMed ID: 24722782
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
