These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

223 related articles for article (PubMed ID: 34107280)

  • 1. Structural Insights into the Mechanism of Base Excision by MBD4.
    Pidugu LS; Bright H; Lin WJ; Majumdar C; Van Ostrand RP; David SS; Pozharski E; Drohat AC
    J Mol Biol; 2021 Jul; 433(15):167097. PubMed ID: 34107280
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Crystal structure of human methyl-binding domain IV glycosylase bound to abasic DNA.
    Manvilla BA; Maiti A; Begley MC; Toth EA; Drohat AC
    J Mol Biol; 2012 Jul; 420(3):164-75. PubMed ID: 22560993
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Excision of thymine and 5-hydroxymethyluracil by the MBD4 DNA glycosylase domain: structural basis and implications for active DNA demethylation.
    Hashimoto H; Zhang X; Cheng X
    Nucleic Acids Res; 2012 Sep; 40(17):8276-84. PubMed ID: 22740654
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Insights into the substrate discrimination mechanisms of methyl-CpG-binding domain 4.
    Ouzon-Shubeita H; Schmaltz LF; Lee S
    Biochem J; 2021 May; 478(10):1985-1997. PubMed ID: 33960375
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Catalytic mechanism of the mismatch-specific DNA glycosylase methyl-CpG-binding domain 4.
    Ouzon-Shubeita H; Jung H; Lee MH; Koag MC; Lee S
    Biochem J; 2020 May; 477(9):1601-1612. PubMed ID: 32297632
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Biochemical and structural characterization of the glycosylase domain of MBD4 bound to thymine and 5-hydroxymethyuracil-containing DNA.
    Moréra S; Grin I; Vigouroux A; Couvé S; Henriot V; Saparbaev M; Ishchenko AA
    Nucleic Acids Res; 2012 Oct; 40(19):9917-26. PubMed ID: 22848106
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Crystal structure of the mismatch-specific thymine glycosylase domain of human methyl-CpG-binding protein MBD4.
    Zhang W; Liu Z; Crombet L; Amaya MF; Liu Y; Zhang X; Kuang W; Ma P; Niu L; Qi C
    Biochem Biophys Res Commun; 2011 Sep; 412(3):425-8. PubMed ID: 21820404
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Role of base excision repair in maintaining the genetic and epigenetic integrity of CpG sites.
    Bellacosa A; Drohat AC
    DNA Repair (Amst); 2015 Aug; 32():33-42. PubMed ID: 26021671
    [TBL] [Abstract][Full Text] [Related]  

  • 9. MBD4 and TDG: multifaceted DNA glycosylases with ever expanding biological roles.
    Sjolund AB; Senejani AG; Sweasy JB
    Mutat Res; 2013; 743-744():12-25. PubMed ID: 23195996
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structural basis of the versatile DNA recognition ability of the methyl-CpG binding domain of methyl-CpG binding domain protein 4.
    Otani J; Arita K; Kato T; Kinoshita M; Kimura H; Suetake I; Tajima S; Ariyoshi M; Shirakawa M
    J Biol Chem; 2013 Mar; 288(9):6351-62. PubMed ID: 23316048
    [TBL] [Abstract][Full Text] [Related]  

  • 11. [Structure basis of versatile base recognition of MBD4].
    Ariyoshi M; Otani J; Shirakawa M
    Yakugaku Zasshi; 2015; 135(1):3-9. PubMed ID: 25743892
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Thymine DNA glycosylase exhibits negligible affinity for nucleobases that it removes from DNA.
    Malik SS; Coey CT; Varney KM; Pozharski E; Drohat AC
    Nucleic Acids Res; 2015 Oct; 43(19):9541-52. PubMed ID: 26358812
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structural and mutation studies of two DNA demethylation related glycosylases: MBD4 and TDG.
    Hashimoto H
    Biophysics (Nagoya-shi); 2014; 10():63-8. PubMed ID: 27493500
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Molecular characterization of a putative plant homolog of MBD4 DNA glycosylase.
    Ramiro-Merina Á; Ariza RR; Roldán-Arjona T
    DNA Repair (Amst); 2013 Nov; 12(11):890-8. PubMed ID: 23994068
    [TBL] [Abstract][Full Text] [Related]  

  • 15. DNA bending and a flip-out mechanism for base excision by the helix-hairpin-helix DNA glycosylase, Escherichia coli AlkA.
    Hollis T; Ichikawa Y; Ellenberger T
    EMBO J; 2000 Feb; 19(4):758-66. PubMed ID: 10675345
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structure and activity of a thermostable thymine-DNA glycosylase: evidence for base twisting to remove mismatched normal DNA bases.
    Mol CD; Arvai AS; Begley TJ; Cunningham RP; Tainer JA
    J Mol Biol; 2002 Jan; 315(3):373-84. PubMed ID: 11786018
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Lesion processing by a repair enzyme is severely curtailed by residues needed to prevent aberrant activity on undamaged DNA.
    Maiti A; Noon MS; MacKerell AD; Pozharski E; Drohat AC
    Proc Natl Acad Sci U S A; 2012 May; 109(21):8091-6. PubMed ID: 22573813
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Crystal structure of a G:T/U mismatch-specific DNA glycosylase: mismatch recognition by complementary-strand interactions.
    Barrett TE; Savva R; Panayotou G; Barlow T; Brown T; Jiricny J; Pearl LH
    Cell; 1998 Jan; 92(1):117-29. PubMed ID: 9489705
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Human thymine DNA glycosylase (TDG) and methyl-CpG-binding protein 4 (MBD4) excise thymine glycol (Tg) from a Tg:G mispair.
    Yoon JH; Iwai S; O'Connor TR; Pfeifer GP
    Nucleic Acids Res; 2003 Sep; 31(18):5399-404. PubMed ID: 12954776
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Modulation of the activity of methyl binding domain protein 4 (MBD4/MED1) while processing iododeoxyuridine generated DNA mispairs.
    Aziz MA; Schupp JE; Kinsella TJ
    Cancer Biol Ther; 2009 Jun; 8(12):1156-63. PubMed ID: 19395862
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.