161 related articles for article (PubMed ID: 34107837)
1. Methoxy and bromo scans on
González M; Ovejero-Sánchez M; Vicente-Blázquez A; Medarde M; González-Sarmiento R; Peláez R
J Enzyme Inhib Med Chem; 2021 Dec; 36(1):1029-1047. PubMed ID: 34107837
[TBL] [Abstract][Full Text] [Related]
2. Synthesis, biological evaluation, and molecular modelling of new naphthalene-chalcone derivatives as potential anticancer agents on MCF-7 breast cancer cells by targeting tubulin colchicine binding site.
Wang G; Liu W; Gong Z; Huang Y; Li Y; Peng Z
J Enzyme Inhib Med Chem; 2020 Dec; 35(1):139-144. PubMed ID: 31724435
[TBL] [Abstract][Full Text] [Related]
3. Synthesis and biological evaluation of podophyllotoxin congeners as tubulin polymerization inhibitors.
Kamal A; Srinivasa Reddy T; Polepalli S; Shalini N; Reddy VG; Subba Rao AV; Jain N; Shankaraiah N
Bioorg Med Chem; 2014 Oct; 22(19):5466-75. PubMed ID: 25131956
[TBL] [Abstract][Full Text] [Related]
4. Design, synthesis, in vitro antiproliferative activity and apoptosis-inducing studies of 1-(3',4',5'-trimethoxyphenyl)-3-(2'-alkoxycarbonylindolyl)-2-propen-1-one derivatives obtained by a molecular hybridisation approach.
Preti D; Romagnoli R; Rondanin R; Cacciari B; Hamel E; Balzarini J; Liekens S; Schols D; Estévez-Sarmiento F; Quintana J; Estévez F
J Enzyme Inhib Med Chem; 2018 Dec; 33(1):1225-1238. PubMed ID: 30141353
[TBL] [Abstract][Full Text] [Related]
5. β-Lactams with antiproliferative and antiapoptotic activity in breast and chemoresistant colon cancer cells.
Malebari AM; Fayne D; Nathwani SM; O'Connell F; Noorani S; Twamley B; O'Boyle NM; O'Sullivan J; Zisterer DM; Meegan MJ
Eur J Med Chem; 2020 Mar; 189():112050. PubMed ID: 31954879
[TBL] [Abstract][Full Text] [Related]
6. Synthesis and evaluation of stilbene and dihydrostilbene derivatives as potential anticancer agents that inhibit tubulin polymerization.
Cushman M; Nagarathnam D; Gopal D; Chakraborti AK; Lin CM; Hamel E
J Med Chem; 1991 Aug; 34(8):2579-88. PubMed ID: 1875350
[TBL] [Abstract][Full Text] [Related]
7. 5-(Furan-2-yl)-4-(3,4,5-trimethoxyphenyl)-3H-1,2-dithiol-3-one oxime (6f), a new synthetic compound, causes human fibrosarcoma HT-1080 cell apoptosis by disrupting tubulin polymerisation and inducing G2/M arrest.
Zuo D; Pang L; Shen J; Guan Q; Bai Z; Zhang H; Li Y; Lu G; Zhang W; Wu Y
Int J Oncol; 2017 Jun; 50(6):2069-2078. PubMed ID: 28440465
[TBL] [Abstract][Full Text] [Related]
8. Biological Activity, Apoptotic Induction and Cell Cycle Arrest of New Hydrazonoyl Halides Derivatives.
Mohamed MF; Hassaneen HM; Elzayat EM; El-Hallouty SM; El-Manawaty M; Saleh FM; Mohamed Y; El-Zohiry D; Fahmy G; Abdelaal N; Hassanin N; Hossam N
Anticancer Agents Med Chem; 2019; 19(9):1141-1149. PubMed ID: 30843494
[TBL] [Abstract][Full Text] [Related]
9. Synthesis and Antiproliferative Evaluation of 3-Chloroazetidin-2-ones with Antimitotic Activity: Heterocyclic Bridged Analogues of Combretastatin A-4.
Malebari AM; Wang S; Greene TF; O'Boyle NM; Fayne D; Khan MF; Nathwani SM; Twamley B; McCabe T; Zisterer DM; Meegan MJ
Pharmaceuticals (Basel); 2021 Oct; 14(11):. PubMed ID: 34832901
[TBL] [Abstract][Full Text] [Related]
10. (E)-N-Aryl-2-oxo-2-(3,4,5-trimethoxyphenyl)acetohydrazonoyl cyanides as tubulin polymerization inhibitors: Structure-based bioisosterism design, synthesis, biological evaluation, molecular docking and in silico ADME prediction.
Wang G; Peng Z; Peng S; Qiu J; Li Y; Lan Y
Bioorg Med Chem Lett; 2018 Nov; 28(20):3350-3355. PubMed ID: 30197030
[TBL] [Abstract][Full Text] [Related]
11. Design, synthesis and biological evaluation of a novel tubulin inhibitor 7a3 targeting the colchicine binding site.
Lai Q; Wang Y; Wang R; Lai W; Tang L; Tao Y; Liu Y; Zhang R; Huang L; Xiang H; Zeng S; Gou L; Chen H; Yao Y; Yang J
Eur J Med Chem; 2018 Aug; 156():162-179. PubMed ID: 30006162
[TBL] [Abstract][Full Text] [Related]
12. Phenyl 4-(2-oxopyrrolidin-1-yl)benzenesulfonates and phenyl 4-(2-oxopyrrolidin-1-yl)benzenesulfonamides as new antimicrotubule agents targeting the colchicine-binding site.
Gagné-Boulet M; Bouzriba C; Chavez Alvarez AC; Fortin S
Eur J Med Chem; 2021 Mar; 213():113136. PubMed ID: 33472119
[TBL] [Abstract][Full Text] [Related]
13. Design and synthesis of substituted dihydropyrimidinone derivatives as cytotoxic and tubulin polymerization inhibitors.
Sana S; Tokala R; Bajaj DM; Nagesh N; Bokara KK; Kiranmai G; Lakshmi UJ; Vadlamani S; Talla V; Shankaraiah N
Bioorg Chem; 2019 Dec; 93():103317. PubMed ID: 31586714
[TBL] [Abstract][Full Text] [Related]
14. Cytotoxic substituted indolizines as new colchicine site tubulin polymerisation inhibitors.
Sardaru MC; Craciun AM; Al Matarneh CM; Sandu IA; Amarandi RM; Popovici L; Ciobanu CI; Peptanariu D; Pinteala M; Mangalagiu II; Danac R
J Enzyme Inhib Med Chem; 2020 Dec; 35(1):1581-1595. PubMed ID: 32752898
[TBL] [Abstract][Full Text] [Related]
15. Synthesis and Evaluation of 2-Naphthaleno trans-Stilbenes and Cyanostilbenes as Anticancer Agents.
Madadi NR; Penthala NR; Ketkar A; Eoff RL; Trujullo-Alonso V; Guzman ML; Crooks PA
Anticancer Agents Med Chem; 2018; 18(4):556-564. PubMed ID: 28403783
[TBL] [Abstract][Full Text] [Related]
16. Synthesis and Biochemical Evaluation of 3-Phenoxy-1,4-diarylazetidin-2-ones as Tubulin-Targeting Antitumor Agents.
Greene TF; Wang S; Greene LM; Nathwani SM; Pollock JK; Malebari AM; McCabe T; Twamley B; O'Boyle NM; Zisterer DM; Meegan MJ
J Med Chem; 2016 Jan; 59(1):90-113. PubMed ID: 26680364
[TBL] [Abstract][Full Text] [Related]
17. 3-Vinylazetidin-2-Ones: Synthesis, Antiproliferative and Tubulin Destabilizing Activity in MCF-7 and MDA-MB-231 Breast Cancer Cells.
Wang S; Malebari AM; Greene TF; O'Boyle NM; Fayne D; Nathwani SM; Twamley B; McCabe T; Keely NO; Zisterer DM; Meegan MJ
Pharmaceuticals (Basel); 2019 Apr; 12(2):. PubMed ID: 30979033
[TBL] [Abstract][Full Text] [Related]
18. Methoxy-substituted 3-formyl-2-phenylindoles inhibit tubulin polymerization.
Gastpar R; Goldbrunner M; Marko D; von Angerer E
J Med Chem; 1998 Dec; 41(25):4965-72. PubMed ID: 9836614
[TBL] [Abstract][Full Text] [Related]
19. Antiproliferative Activity of 8-methoxy Ciprofloxacin-Hydrozone/Acylhydrazone Scaffolds.
Wang LP; Xu Z; Deng GY; Xu SL
Curr Top Med Chem; 2020; 20(21):1911-1915. PubMed ID: 32493190
[TBL] [Abstract][Full Text] [Related]
20. BPR0L075, a novel synthetic indole compound with antimitotic activity in human cancer cells, exerts effective antitumoral activity in vivo.
Kuo CC; Hsieh HP; Pan WY; Chen CP; Liou JP; Lee SJ; Chang YL; Chen LT; Chen CT; Chang JY
Cancer Res; 2004 Jul; 64(13):4621-8. PubMed ID: 15231674
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
