BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

179 related articles for article (PubMed ID: 34108262)

  • 1. International Consensus on Minimum Preclinical Testing Requirements for the Development of Innovative Therapies For Children and Adolescents with Cancer.
    Vassal G; Houghton PJ; Pfister SM; Smith MA; Caron HN; Li XN; Shields DJ; Witt O; Molenaar JJ; Colombetti S; Schüler J; Stancato LF
    Mol Cancer Ther; 2021 Aug; 20(8):1462-1468. PubMed ID: 34108262
    [TBL] [Abstract][Full Text] [Related]  

  • 2. New insights into drug development for pediatric solid tumors: what preclinical data justify clinical trials in pediatric cancer?
    Houghton PJ
    Expert Rev Anticancer Ther; 2013 Oct; 13(10):1135-8. PubMed ID: 24093514
    [No Abstract]   [Full Text] [Related]  

  • 3. Targeted agents: how to select the winners in preclinical and early clinical studies?
    Goodwin R; Giaccone G; Calvert H; Lobbezoo M; Eisenhauer EA
    Eur J Cancer; 2012 Jan; 48(2):170-8. PubMed ID: 22093946
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Navigating the Regulatory Landscape to Develop Pediatric Oncology Drugs: Expert Opinion Recommendations.
    Barry E; Walsh JA; Weinrich SL; Beaupre D; Blasi E; Arenson DR; Jacobs IA
    Paediatr Drugs; 2021 Jul; 23(4):381-394. PubMed ID: 34173206
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Paediatric Strategy Forum for medicinal product development of epigenetic modifiers for children: ACCELERATE in collaboration with the European Medicines Agency with participation of the Food and Drug Administration.
    Pearson AD; Stegmaier K; Bourdeaut F; Reaman G; Heenen D; Meyers ML; Armstrong SA; Brown P; De Carvalho D; Jabado N; Marshall L; Rivera M; Smith M; Adamson PC; Barone A; Baumann C; Blackman S; Buenger V; Donoghue M; Duncan AD; Fox E; Gadbaw B; Hattersley M; Ho P; Jacobs I; Kelly MJ; Kieran M; Lesa G; Ligas F; Ludwinski D; McDonough J; Nikolova Z; Norga K; Senderowicz A; Taube T; Weiner S; Karres D; Vassal G
    Eur J Cancer; 2020 Nov; 139():135-148. PubMed ID: 32992153
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Preclinical models for pediatric solid tumor drug discovery: current trends, challenges and the scopes for improvement.
    Kumar S; Mokhtari RB; Yeger H; Baruchel S
    Expert Opin Drug Discov; 2012 Nov; 7(11):1093-106. PubMed ID: 22998522
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The future of Cochrane Neonatal.
    Soll RF; Ovelman C; McGuire W
    Early Hum Dev; 2020 Nov; 150():105191. PubMed ID: 33036834
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Safety assessment of biotechnology-derived pharmaceuticals: ICH and beyond.
    Serabian MA; Pilaro AM
    Toxicol Pathol; 1999; 27(1):27-31. PubMed ID: 10367669
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Accelerating drug development for neuroblastoma - New Drug Development Strategy: an Innovative Therapies for Children with Cancer, European Network for Cancer Research in Children and Adolescents and International Society of Paediatric Oncology Europe Neuroblastoma project.
    Moreno L; Caron H; Geoerger B; Eggert A; Schleiermacher G; Brock P; Valteau-Couanet D; Chesler L; Schulte JH; De Preter K; Molenaar J; Schramm A; Eilers M; Van Maerken T; Johnsen JI; Garrett M; George SL; Tweddle DA; Kogner P; Berthold F; Koster J; Barone G; Tucker ER; Marshall L; Herold R; Sterba J; Norga K; Vassal G; Pearson AD
    Expert Opin Drug Discov; 2017 Aug; 12(8):801-811. PubMed ID: 28604107
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Predictors of Success of Phase II Pediatric Oncology Clinical Trials.
    Franshaw L; Tsoli M; Byrne J; Mayoh C; Sivarajasingam S; Norris M; Marshall GM; Ziegler DS
    Oncologist; 2019 Aug; 24(8):e765-e774. PubMed ID: 30808815
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Development of an NIH consortium for preclinicAl AssESsment of CARdioprotective therapies (CAESAR): a paradigm shift in studies of infarct size limitation.
    Lefer DJ; Bolli R
    J Cardiovasc Pharmacol Ther; 2011; 16(3-4):332-9. PubMed ID: 21821536
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Rescuing Drugs That are Discontinued in Adult Oncology Development for the Benefit of Children and Adolescents With Cancer - An ACCELERATE Multistakeholder Consensus.
    de Rojas T; Chiodin D; Pearson ADJ; Heenen D; Adamson P; Caron H; Vassal G
    Clin Pharmacol Ther; 2024 Jan; 115(1):36-41. PubMed ID: 37885401
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Broad Spectrum Activity of the Checkpoint Kinase 1 Inhibitor Prexasertib as a Single Agent or Chemopotentiator Across a Range of Preclinical Pediatric Tumor Models.
    Lowery CD; Dowless M; Renschler M; Blosser W; VanWye AB; Stephens JR; Iversen PW; Lin AB; Beckmann RP; Krytska K; Cole KA; Maris JM; Hawkins DS; Rubin BP; Kurmasheva RT; Houghton PJ; Gorlick R; Kolb EA; Kang MH; Reynolds CP; Erickson SW; Teicher BA; Smith MA; Stancato LF
    Clin Cancer Res; 2019 Apr; 25(7):2278-2289. PubMed ID: 30563935
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Pediatric Trials for Cancer Therapies With Targets Potentially Relevant to Pediatric Cancers.
    Hwang TJ; Orenstein L; DuBois SG; Janeway KA; Bourgeois FT
    J Natl Cancer Inst; 2020 Mar; 112(3):224-228. PubMed ID: 31665394
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Harnessing preclinical mouse models to inform human clinical cancer trials.
    Gutmann DH; Hunter-Schaedle K; Shannon KM
    J Clin Invest; 2006 Apr; 116(4):847-52. PubMed ID: 16585951
    [TBL] [Abstract][Full Text] [Related]  

  • 16. An FDA oncology view of juvenile animal studies in support of initial pediatric trials for anticancer drugs.
    Leighton JK; Saber H; Reaman G; Pazdur R
    Regul Toxicol Pharmacol; 2016 Aug; 79():142-143. PubMed ID: 26952647
    [No Abstract]   [Full Text] [Related]  

  • 17. The role of the 'innovative therapies for children with cancer' (ITCC) European consortium.
    Zwaan CM; Kearns P; Caron H; Verschuur A; Riccardi R; Boos J; Doz F; Geoerger B; Morland B; Vassal G;
    Cancer Treat Rev; 2010 Jun; 36(4):328-34. PubMed ID: 20231057
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Design and conduct of early clinical studies of two or more targeted anticancer therapies: recommendations from the task force on Methodology for the Development of Innovative Cancer Therapies.
    Seymour LK; Calvert AH; Lobbezoo MW; Eisenhauer EA; Giaccone G;
    Eur J Cancer; 2013 May; 49(8):1808-14. PubMed ID: 23428669
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Designing innovative therapies for neuropathic pain: preclinical and early clinical development challenges.
    Höke A; Simpson DM; Freeman R
    J Peripher Nerv Syst; 2014 Oct; 19 Suppl 2():S28-9. PubMed ID: 25269739
    [No Abstract]   [Full Text] [Related]  

  • 20. Initial testing of topotecan by the pediatric preclinical testing program.
    Carol H; Houghton PJ; Morton CL; Kolb EA; Gorlick R; Reynolds CP; Kang MH; Maris JM; Keir ST; Watkins A; Smith MA; Lock RB
    Pediatr Blood Cancer; 2010 May; 54(5):707-15. PubMed ID: 20017204
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.