BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

315 related articles for article (PubMed ID: 34108651)

  • 1. Role of TRPM2 in brain tumours and potential as a drug target.
    Ji D; Luo ZW; Ovcjak A; Alanazi R; Bao MH; Feng ZP; Sun HS
    Acta Pharmacol Sin; 2022 Apr; 43(4):759-770. PubMed ID: 34108651
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Ligand-induced activation of human TRPM2 requires the terminal ribose of ADPR and involves Arg1433 and Tyr1349.
    Fliegert R; Watt JM; Schöbel A; Rozewitz MD; Moreau C; Kirchberger T; Thomas MP; Sick W; Araujo AC; Harneit A; Potter BVL; Guse AH
    Biochem J; 2017 Jun; 474(13):2159-2175. PubMed ID: 28515263
    [TBL] [Abstract][Full Text] [Related]  

  • 3. TRPM2: a calcium influx pathway regulated by oxidative stress and the novel second messenger ADP-ribose.
    Kühn FJ; Heiner I; Lückhoff A
    Pflugers Arch; 2005 Oct; 451(1):212-9. PubMed ID: 15952035
    [TBL] [Abstract][Full Text] [Related]  

  • 4. TRPM2: a multifunctional ion channel for oxidative stress sensing.
    Ru X; Yao X
    Sheng Li Xue Bao; 2014 Feb; 66(1):7-15. PubMed ID: 24553864
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A calcium influx pathway regulated separately by oxidative stress and ADP-Ribose in TRPM2 channels: single channel events.
    Naziroğlu M; Lückhoff A
    Neurochem Res; 2008 Jul; 33(7):1256-62. PubMed ID: 18259858
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Accumulation of free ADP-ribose from mitochondria mediates oxidative stress-induced gating of TRPM2 cation channels.
    Perraud AL; Takanishi CL; Shen B; Kang S; Smith MK; Schmitz C; Knowles HM; Ferraris D; Li W; Zhang J; Stoddard BL; Scharenberg AM
    J Biol Chem; 2005 Feb; 280(7):6138-48. PubMed ID: 15561722
    [TBL] [Abstract][Full Text] [Related]  

  • 7. TRPM2 cation channels, oxidative stress and neurological diseases: where are we now?
    Nazıroğlu M
    Neurochem Res; 2011 Mar; 36(3):355-66. PubMed ID: 21140288
    [TBL] [Abstract][Full Text] [Related]  

  • 8. TRPM2 channel opening in response to oxidative stress is dependent on activation of poly(ADP-ribose) polymerase.
    Fonfria E; Marshall IC; Benham CD; Boyfield I; Brown JD; Hill K; Hughes JP; Skaper SD; McNulty S
    Br J Pharmacol; 2004 Sep; 143(1):186-92. PubMed ID: 15302683
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Identification of the ADPR binding pocket in the NUDT9 homology domain of TRPM2.
    Yu P; Xue X; Zhang J; Hu X; Wu Y; Jiang LH; Jin H; Luo J; Zhang L; Liu Z; Yang W
    J Gen Physiol; 2017 Feb; 149(2):219-235. PubMed ID: 28108595
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Identification of direct and indirect effectors of the transient receptor potential melastatin 2 (TRPM2) cation channel.
    Tóth B; Csanády L
    J Biol Chem; 2010 Sep; 285(39):30091-102. PubMed ID: 20650899
    [TBL] [Abstract][Full Text] [Related]  

  • 11. TRPM2 channel membrane currents in primary rat megakaryocytes were activated by the agonist ADP-ribose but not oxidative stress.
    Nazıroğlu M
    J Membr Biol; 2011 May; 241(2):51-7. PubMed ID: 21512734
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structures and gating mechanism of human TRPM2.
    Wang L; Fu TM; Zhou Y; Xia S; Greka A; Wu H
    Science; 2018 Dec; 362(6421):. PubMed ID: 30467180
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Sites of the NUDT9-H domain critical for ADP-ribose activation of the cation channel TRPM2.
    Kühn FJ; Lückhoff A
    J Biol Chem; 2004 Nov; 279(45):46431-7. PubMed ID: 15347676
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Hydrogen peroxide and ADP-ribose induce TRPM2-mediated calcium influx and cation currents in microglia.
    Kraft R; Grimm C; Grosse K; Hoffmann A; Sauerbruch S; Kettenmann H; Schultz G; Harteneck C
    Am J Physiol Cell Physiol; 2004 Jan; 286(1):C129-37. PubMed ID: 14512294
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Architecture of the TRPM2 channel and its activation mechanism by ADP-ribose and calcium.
    Huang Y; Winkler PA; Sun W; Lü W; Du J
    Nature; 2018 Oct; 562(7725):145-149. PubMed ID: 30250252
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The Role of TRPM2 in Endothelial Function and Dysfunction.
    Zielińska W; Zabrzyński J; Gagat M; Grzanka A
    Int J Mol Sci; 2021 Jul; 22(14):. PubMed ID: 34299254
    [TBL] [Abstract][Full Text] [Related]  

  • 17. New molecular mechanisms on the activation of TRPM2 channels by oxidative stress and ADP-ribose.
    Naziroğlu M
    Neurochem Res; 2007 Nov; 32(11):1990-2001. PubMed ID: 17562166
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Role of TRPM2 channel in mediating H2O2-induced Ca2+ entry and endothelial hyperpermeability.
    Hecquet CM; Ahmmed GU; Vogel SM; Malik AB
    Circ Res; 2008 Feb; 102(3):347-55. PubMed ID: 18048770
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Aminoethoxydiphenyl borate and flufenamic acid inhibit Ca2+ influx through TRPM2 channels in rat dorsal root ganglion neurons activated by ADP-ribose and rotenone.
    Nazıroğlu M; Özgül C; Çelik Ö; Çiğ B; Sözbir E
    J Membr Biol; 2011 May; 241(2):69-75. PubMed ID: 21509529
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Sensitization of H2O2-induced TRPM2 activation and subsequent interleukin-8 (CXCL8) production by intracellular Fe(2+) in human monocytic U937 cells.
    Shimizu S; Yonezawa R; Negoro T; Yamamoto S; Numata T; Ishii M; Mori Y; Toda T
    Int J Biochem Cell Biol; 2015 Nov; 68():119-27. PubMed ID: 26386353
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.