BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

303 related articles for article (PubMed ID: 34113392)

  • 1. LZTR1: A promising adaptor of the CUL3 family.
    Zhang H; Cao X; Wang J; Li Q; Zhao Y; Jin X
    Oncol Lett; 2021 Jul; 22(1):564. PubMed ID: 34113392
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Dominant Noonan syndrome-causing LZTR1 mutations specifically affect the Kelch domain substrate-recognition surface and enhance RAS-MAPK signaling.
    Motta M; Fidan M; Bellacchio E; Pantaleoni F; Schneider-Heieck K; Coppola S; Borck G; Salviati L; Zenker M; Cirstea IC; Tartaglia M
    Hum Mol Genet; 2019 Mar; 28(6):1007-1022. PubMed ID: 30481304
    [TBL] [Abstract][Full Text] [Related]  

  • 3. LZTR1 facilitates polyubiquitination and degradation of RAS-GTPases.
    Abe T; Umeki I; Kanno SI; Inoue SI; Niihori T; Aoki Y
    Cell Death Differ; 2020 Mar; 27(3):1023-1035. PubMed ID: 31337872
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mutations in LZTR1 drive human disease by dysregulating RAS ubiquitination.
    Steklov M; Pandolfi S; Baietti MF; Batiuk A; Carai P; Najm P; Zhang M; Jang H; Renzi F; Cai Y; Abbasi Asbagh L; Pastor T; De Troyer M; Simicek M; Radaelli E; Brems H; Legius E; Tavernier J; Gevaert K; Impens F; Messiaen L; Nussinov R; Heymans S; Eyckerman S; Sablina AA
    Science; 2018 Dec; 362(6419):1177-1182. PubMed ID: 30442762
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The Noonan Syndrome Gene
    Sewduth RN; Pandolfi S; Steklov M; Sheryazdanova A; Zhao P; Criem N; Baietti MF; Lechat B; Quarck R; Impens F; Sablina AA
    Circ Res; 2020 May; 126(10):1379-1393. PubMed ID: 32175818
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structural Model for Recruitment of RIT1 to the LZTR1 E3 Ligase: Evidences from an Integrated Computational Approach.
    Paladino A; D'Angelo F; Noviello TMR; Iavarone A; Ceccarelli M
    J Chem Inf Model; 2021 Apr; 61(4):1875-1888. PubMed ID: 33792302
    [TBL] [Abstract][Full Text] [Related]  

  • 7. LZTR1 deficiency exerts high metastatic potential by enhancing sensitivity to EMT induction and controlling KLHL12-mediated collagen secretion.
    Abe T; Kanno SI; Niihori T; Terao M; Takada S; Aoki Y
    Cell Death Dis; 2023 Aug; 14(8):556. PubMed ID: 37626065
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cross-species analysis of LZTR1 loss-of-function mutants demonstrates dependency to RIT1 orthologs.
    Cuevas-Navarro A; Rodriguez-Muñoz L; Grego-Bessa J; Cheng A; Rauen KA; Urisman A; McCormick F; Jimenez G; Castel P
    Elife; 2022 Apr; 11():. PubMed ID: 35467524
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Noonan syndrome-associated biallelic LZTR1 mutations cause cardiac hypertrophy and vascular malformations in zebrafish.
    Nakagama Y; Takeda N; Ogawa S; Takeda H; Furutani Y; Nakanishi T; Sato T; Hirata Y; Oka A; Inuzuka R
    Mol Genet Genomic Med; 2020 Mar; 8(3):e1107. PubMed ID: 31883238
    [TBL] [Abstract][Full Text] [Related]  

  • 10. LZTR1 is a regulator of RAS ubiquitination and signaling.
    Bigenzahn JW; Collu GM; Kartnig F; Pieraks M; Vladimer GI; Heinz LX; Sedlyarov V; Schischlik F; Fauster A; Rebsamen M; Parapatics K; Blomen VA; Müller AC; Winter GE; Kralovics R; Brummelkamp TR; Mlodzik M; Superti-Furga G
    Science; 2018 Dec; 362(6419):1171-1177. PubMed ID: 30442766
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cullin 3 and Its Role in Tumorigenesis.
    Chen RH
    Adv Exp Med Biol; 2020; 1217():187-210. PubMed ID: 31898229
    [TBL] [Abstract][Full Text] [Related]  

  • 12. LZTR1 Mutation Mediates Oncogenesis through Stabilization of EGFR and AXL.
    Ko A; Hasanain M; Oh YT; D'Angelo F; Sommer D; Frangaj B; Tran S; Bielle F; Pollo B; Paterra R; Mokhtari K; Soni RK; Peyre M; Eoli M; Papi L; Kalamarides M; Sanson M; Iavarone A; Lasorella A
    Cancer Discov; 2023 Mar; 13(3):702-723. PubMed ID: 36445254
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Generation of a Mouse Model to Study the Noonan Syndrome Gene
    Talley MJ; Nardini D; Shabbir N; Ehrman LA; Prada CE; Waclaw RR
    Front Cell Dev Biol; 2021; 9():673995. PubMed ID: 34222248
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Oligo-astrocytoma in LZTR1-related Noonan syndrome.
    Jacquinet A; Bonnard A; Capri Y; Martin D; Sadzot B; Bianchi E; Servais L; Sacré JP; Cavé H; Verloes A
    Eur J Med Genet; 2020 Jan; 63(1):103617. PubMed ID: 30664951
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Impaired Proteolysis of Noncanonical RAS Proteins Drives Clonal Hematopoietic Transformation.
    Chen S; Vedula RS; Cuevas-Navarro A; Lu B; Hogg SJ; Wang E; Benbarche S; Knorr K; Kim WJ; Stanley RF; Cho H; Erickson C; Singer M; Cui D; Tittley S; Durham BH; Pavletich TS; Fiala E; Walsh MF; Inoue D; Monette S; Taylor J; Rosen N; McCormick F; Lindsley RC; Castel P; Abdel-Wahab O
    Cancer Discov; 2022 Oct; 12(10):2434-2453. PubMed ID: 35904492
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Rare variants in SOS2 and LZTR1 are associated with Noonan syndrome.
    Yamamoto GL; Aguena M; Gos M; Hung C; Pilch J; Fahiminiya S; Abramowicz A; Cristian I; Buscarilli M; Naslavsky MS; Malaquias AC; Zatz M; Bodamer O; Majewski J; Jorge AA; Pereira AC; Kim CA; Passos-Bueno MR; Bertola DR
    J Med Genet; 2015 Jun; 52(6):413-21. PubMed ID: 25795793
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A Comprehensive Pan-Cancer Analysis of the Tumorigenic Effect of Leucine-Zipper-Like Transcription Regulator (LZTR1) in Human Cancer.
    Zhou B; Ying X; Chen Y; Cai X
    Oxid Med Cell Longev; 2022; 2022():2663748. PubMed ID: 36304963
    [TBL] [Abstract][Full Text] [Related]  

  • 18. LZTR1 molecular genetic overlap with clinical implications for Noonan syndrome and schwannomatosis.
    Farncombe KM; Thain E; Barnett-Tapia C; Sadeghian H; Kim RH
    BMC Med Genomics; 2022 Jul; 15(1):160. PubMed ID: 35840934
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Coexistence of schwannomatosis and glioblastoma in two families.
    Deiller C; Van-Gils J; Zordan C; Tinat J; Loiseau H; Fabre T; Delleci C; Cohen J; Vidaud M; Parfait B; Goizet C
    Eur J Med Genet; 2019 Aug; 62(8):103680. PubMed ID: 31128261
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Providing more evidence on LZTR1 variants in Noonan syndrome patients.
    Chinton J; Huckstadt V; Mucciolo M; Lepri F; Novelli A; Gravina LP; Obregon MG
    Am J Med Genet A; 2020 Feb; 182(2):409-414. PubMed ID: 31825158
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.