BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

227 related articles for article (PubMed ID: 34117802)

  • 1. MT5-MMP controls APP and β-CTF/C99 metabolism through proteolytic-dependent and -independent mechanisms relevant for Alzheimer's disease.
    García-González L; Paumier JM; Louis L; Pilat D; Bernard A; Stephan D; Jullien N; Checler F; Nivet E; Khrestchatisky M; Baranger K; Rivera S
    FASEB J; 2021 Jul; 35(7):e21727. PubMed ID: 34117802
    [TBL] [Abstract][Full Text] [Related]  

  • 2. MT5-MMP is a new pro-amyloidogenic proteinase that promotes amyloid pathology and cognitive decline in a transgenic mouse model of Alzheimer's disease.
    Baranger K; Marchalant Y; Bonnet AE; Crouzin N; Carrete A; Paumier JM; Py NA; Bernard A; Bauer C; Charrat E; Moschke K; Seiki M; Vignes M; Lichtenthaler SF; Checler F; Khrestchatisky M; Rivera S
    Cell Mol Life Sci; 2016 Jan; 73(1):217-36. PubMed ID: 26202697
    [TBL] [Abstract][Full Text] [Related]  

  • 3. MT5-MMP, just a new APP processing proteinase in Alzheimer's disease?
    Baranger K; Khrestchatisky M; Rivera S
    J Neuroinflammation; 2016 Jun; 13(1):167. PubMed ID: 27349644
    [TBL] [Abstract][Full Text] [Related]  

  • 4. MT5-MMP promotes neuroinflammation, neuronal excitability and Aβ production in primary neuron/astrocyte cultures from the 5xFAD mouse model of Alzheimer's disease.
    Pilat D; Paumier JM; García-González L; Louis L; Stephan D; Manrique C; Khrestchatisky M; Di Pasquale E; Baranger K; Rivera S
    J Neuroinflammation; 2022 Mar; 19(1):65. PubMed ID: 35277173
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Proamyloidogenic effects of membrane type 1 matrix metalloproteinase involve MMP-2 and BACE-1 activities, and the modulation of APP trafficking.
    Paumier JM; Py NA; García-González L; Bernard A; Stephan D; Louis L; Checler F; Khrestchatisky M; Baranger K; Rivera S
    FASEB J; 2019 Feb; 33(2):2910-2927. PubMed ID: 30332299
    [TBL] [Abstract][Full Text] [Related]  

  • 6. η-Secretase processing of APP inhibits neuronal activity in the hippocampus.
    Willem M; Tahirovic S; Busche MA; Ovsepian SV; Chafai M; Kootar S; Hornburg D; Evans LD; Moore S; Daria A; Hampel H; Müller V; Giudici C; Nuscher B; Wenninger-Weinzierl A; Kremmer E; Heneka MT; Thal DR; Giedraitis V; Lannfelt L; Müller U; Livesey FJ; Meissner F; Herms J; Konnerth A; Marie H; Haass C
    Nature; 2015 Oct; 526(7573):443-7. PubMed ID: 26322584
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Identification of binding partners that facilitate membrane-type 5 matrix metalloproteinase (MT5-MMP) processing of amyloid precursor protein.
    Wang H; Lakshmana MK; Fields GB
    J Cell Physiol; 2024 Jun; 239(6):e31218. PubMed ID: 38345408
    [TBL] [Abstract][Full Text] [Related]  

  • 8. MT5-MMP Promotes Alzheimer's Pathogenesis in the Frontal Cortex of 5xFAD Mice and APP Trafficking
    Baranger K; Bonnet AE; Girard SD; Paumier JM; García-González L; Elmanaa W; Bernard A; Charrat E; Stephan D; Bauer C; Moschke K; Lichtenthaler SF; Roman FS; Checler F; Khrestchatisky M; Rivera S
    Front Mol Neurosci; 2016; 9():163. PubMed ID: 28119565
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Zinc and Copper Differentially Modulate Amyloid Precursor Protein Processing by γ-Secretase and Amyloid-β Peptide Production.
    Gerber H; Wu F; Dimitrov M; Garcia Osuna GM; Fraering PC
    J Biol Chem; 2017 Mar; 292(9):3751-3767. PubMed ID: 28096459
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Accumulation of amyloid precursor protein C-terminal fragments triggers mitochondrial structure, function, and mitophagy defects in Alzheimer's disease models and human brains.
    Vaillant-Beuchot L; Mary A; Pardossi-Piquard R; Bourgeois A; Lauritzen I; Eysert F; Kinoshita PF; Cazareth J; Badot C; Fragaki K; Bussiere R; Martin C; Mary R; Bauer C; Pagnotta S; Paquis-Flucklinger V; Buée-Scherrer V; Buée L; Lacas-Gervais S; Checler F; Chami M
    Acta Neuropathol; 2021 Jan; 141(1):39-65. PubMed ID: 33079262
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Amyloid-β protein (Aβ) Glu11 is the major β-secretase site of β-site amyloid-β precursor protein-cleaving enzyme 1(BACE1), and shifting the cleavage site to Aβ Asp1 contributes to Alzheimer pathogenesis.
    Deng Y; Wang Z; Wang R; Zhang X; Zhang S; Wu Y; Staufenbiel M; Cai F; Song W
    Eur J Neurosci; 2013 Jun; 37(12):1962-9. PubMed ID: 23773065
    [TBL] [Abstract][Full Text] [Related]  

  • 12. BACE1 Cleavage Site Selection Critical for Amyloidogenesis and Alzheimer's Pathogenesis.
    Zhang S; Wang Z; Cai F; Zhang M; Wu Y; Zhang J; Song W
    J Neurosci; 2017 Jul; 37(29):6915-6925. PubMed ID: 28626014
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Alternative Selection of β-Site APP-Cleaving Enzyme 1 (BACE1) Cleavage Sites in Amyloid β-Protein Precursor (APP) Harboring Protective and Pathogenic Mutations within the Aβ Sequence.
    Kimura A; Hata S; Suzuki T
    J Biol Chem; 2016 Nov; 291(46):24041-24053. PubMed ID: 27687728
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The η-secretase-derived APP fragment ηCTF is localized in Golgi, endosomes and extracellular vesicles and contributes to Aβ production.
    Afram E; Lauritzen I; Bourgeois A; El Manaa W; Duplan E; Chami M; Valverde A; Charlotte B; Pardossi-Piquard R; Checler F
    Cell Mol Life Sci; 2023 Mar; 80(4):97. PubMed ID: 36930302
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Proteolytic processing of the Alzheimer's disease amyloid precursor protein in brain and platelets.
    Evin G; Zhu A; Holsinger RM; Masters CL; Li QX
    J Neurosci Res; 2003 Nov; 74(3):386-92. PubMed ID: 14598315
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Specific antibody binding to the APP672-699 region shifts APP processing from α- to β-cleavage.
    Li S; Deng J; Hou H; Tian J; Giunta B; Wang Y; Sawmiller D; Smith A; Sanberg PR; Obregon D; Mori T; Tan J
    Cell Death Dis; 2014 Aug; 5(8):e1374. PubMed ID: 25118934
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Measuring APP carboxy-terminal fragments.
    Esposito LA
    Methods Mol Biol; 2011; 670():71-84. PubMed ID: 20967584
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The A673T mutation in the amyloid precursor protein reduces the production of β-amyloid protein from its β-carboxyl terminal fragment in cells.
    Kokawa A; Ishihara S; Fujiwara H; Nobuhara M; Iwata M; Ihara Y; Funamoto S
    Acta Neuropathol Commun; 2015 Nov; 3():66. PubMed ID: 26531305
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Amyloid precursor protein processing and retinal pathology in mouse models of Alzheimer's disease.
    Dutescu RM; Li QX; Crowston J; Masters CL; Baird PN; Culvenor JG
    Graefes Arch Clin Exp Ophthalmol; 2009 Sep; 247(9):1213-21. PubMed ID: 19271231
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The Alzheimer's Disease γ-Secretase Generates Higher 42:40 Ratios for β-Amyloid Than for p3 Peptides.
    Siegel G; Gerber H; Koch P; Bruestle O; Fraering PC; Rajendran L
    Cell Rep; 2017 Jun; 19(10):1967-1976. PubMed ID: 28591569
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.