BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

365 related articles for article (PubMed ID: 34121209)

  • 1. Phosphoproteomic identification of ULK substrates reveals VPS15-dependent ULK/VPS34 interplay in the regulation of autophagy.
    Mercer TJ; Ohashi Y; Boeing S; Jefferies HBJ; De Tito S; Flynn H; Tremel S; Zhang W; Wirth M; Frith D; Snijders AP; Williams RL; Tooze SA
    EMBO J; 2021 Jul; 40(14):e105985. PubMed ID: 34121209
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The ingenious ULKs: expanding the repertoire of the ULK complex with phosphoproteomics.
    Mercer TJ; Tooze SA
    Autophagy; 2021 Dec; 17(12):4491-4493. PubMed ID: 34520329
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The C-terminal region of ATG101 bridges ULK1 and PtdIns3K complex in autophagy initiation.
    Kim BW; Jin Y; Kim J; Kim JH; Jung J; Kang S; Kim IY; Kim J; Cheong H; Song HK
    Autophagy; 2018; 14(12):2104-2116. PubMed ID: 30081750
    [TBL] [Abstract][Full Text] [Related]  

  • 4. NRBF2 regulates macroautophagy as a component of Vps34 Complex I.
    Cao Y; Wang Y; Abi Saab WF; Yang F; Pessin JE; Backer JM
    Biochem J; 2014 Jul; 461(2):315-22. PubMed ID: 24785657
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Defects of Vps15 in skeletal muscles lead to autophagic vacuolar myopathy and lysosomal disease.
    Nemazanyy I; Blaauw B; Paolini C; Caillaud C; Protasi F; Mueller A; Proikas-Cezanne T; Russell RC; Guan KL; Nishino I; Sandri M; Pende M; Panasyuk G
    EMBO Mol Med; 2013 Jun; 5(6):870-90. PubMed ID: 23630012
    [TBL] [Abstract][Full Text] [Related]  

  • 6. ULK1 induces autophagy by phosphorylating Beclin-1 and activating VPS34 lipid kinase.
    Russell RC; Tian Y; Yuan H; Park HW; Chang YY; Kim J; Kim H; Neufeld TP; Dillin A; Guan KL
    Nat Cell Biol; 2013 Jul; 15(7):741-50. PubMed ID: 23685627
    [TBL] [Abstract][Full Text] [Related]  

  • 7. ULK1 O-GlcNAcylation Is Crucial for Activating VPS34 via ATG14L during Autophagy Initiation.
    Pyo KE; Kim CR; Lee M; Kim JS; Kim KI; Baek SH
    Cell Rep; 2018 Dec; 25(10):2878-2890.e4. PubMed ID: 30517873
    [TBL] [Abstract][Full Text] [Related]  

  • 8. TNF-induced necroptosis initiates early autophagy events via RIPK3-dependent AMPK activation, but inhibits late autophagy.
    Wu W; Wang X; Sun Y; Berleth N; Deitersen J; Schlütermann D; Stuhldreier F; Wallot-Hieke N; José Mendiburo M; Cox J; Peter C; Bergmann AK; Stork B
    Autophagy; 2021 Dec; 17(12):3992-4009. PubMed ID: 33779513
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Vps34 Kinase Domain Dynamics Regulate the Autophagic PI 3-Kinase Complex.
    Stjepanovic G; Baskaran S; Lin MG; Hurley JH
    Mol Cell; 2017 Aug; 67(3):528-534.e3. PubMed ID: 28757208
    [TBL] [Abstract][Full Text] [Related]  

  • 10. AMPK Inhibits ULK1-Dependent Autophagosome Formation and Lysosomal Acidification via Distinct Mechanisms.
    Nwadike C; Williamson LE; Gallagher LE; Guan JL; Chan EYW
    Mol Cell Biol; 2018 May; 38(10):. PubMed ID: 29507183
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Atg38 is required for autophagy-specific phosphatidylinositol 3-kinase complex integrity.
    Araki Y; Ku WC; Akioka M; May AI; Hayashi Y; Arisaka F; Ishihama Y; Ohsumi Y
    J Cell Biol; 2013 Oct; 203(2):299-313. PubMed ID: 24165940
    [TBL] [Abstract][Full Text] [Related]  

  • 12. RACK1 Promotes Autophagy by Enhancing the Atg14L-Beclin 1-Vps34-Vps15 Complex Formation upon Phosphorylation by AMPK.
    Zhao Y; Wang Q; Qiu G; Zhou S; Jing Z; Wang J; Wang W; Cao J; Han K; Cheng Q; Shen B; Chen Y; Zhang WJ; Ma Y; Zhang J
    Cell Rep; 2015 Nov; 13(7):1407-1417. PubMed ID: 26549445
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Aberrant autophagosome formation occurs upon small molecule inhibition of ULK1 kinase activity.
    Zachari M; Longo M; Ganley IG
    Life Sci Alliance; 2020 Dec; 3(12):. PubMed ID: 33109685
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Autophagic kinases SmVPS34 and SmVPS15 are required for viability in the filamentous ascomycete Sordaria macrospora.
    Voigt O; Herzog B; Jakobshagen A; Pöggeler S
    Microbiol Res; 2014; 169(2-3):128-38. PubMed ID: 23953726
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structural basis for VPS34 kinase activation by Rab1 and Rab5 on membranes.
    Tremel S; Ohashi Y; Morado DR; Bertram J; Perisic O; Brandt LTL; von Wrisberg MK; Chen ZA; Maslen SL; Kovtun O; Skehel M; Rappsilber J; Lang K; Munro S; Briggs JAG; Williams RL
    Nat Commun; 2021 Mar; 12(1):1564. PubMed ID: 33692360
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Canonical autophagy dependent on the class III phosphoinositide-3 kinase Vps34 is required for naive T-cell homeostasis.
    Willinger T; Flavell RA
    Proc Natl Acad Sci U S A; 2012 May; 109(22):8670-5. PubMed ID: 22592798
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A phosphatidylinositol 3-kinase class III sub-complex containing VPS15, VPS34, Beclin 1, UVRAG and BIF-1 regulates cytokinesis and degradative endocytic traffic.
    Thoresen SB; Pedersen NM; Liestøl K; Stenmark H
    Exp Cell Res; 2010 Dec; 316(20):3368-78. PubMed ID: 20643123
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The PI 3-kinase regulator Vps15 is required for autophagic clearance of protein aggregates.
    Lindmo K; Brech A; Finley KD; Gaumer S; Contamine D; Rusten TE; Stenmark H
    Autophagy; 2008 May; 4(4):500-6. PubMed ID: 18326940
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A molecular perspective of mammalian autophagosome biogenesis.
    Mercer TJ; Gubas A; Tooze SA
    J Biol Chem; 2018 Apr; 293(15):5386-5395. PubMed ID: 29371398
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Dynamic association of the ULK1 complex with omegasomes during autophagy induction.
    Karanasios E; Stapleton E; Manifava M; Kaizuka T; Mizushima N; Walker SA; Ktistakis NT
    J Cell Sci; 2013 Nov; 126(Pt 22):5224-38. PubMed ID: 24013547
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.