BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

312 related articles for article (PubMed ID: 34125740)

  • 1. Helenalin Facilitates Reactive Oxygen Species-Mediated Apoptosis and Cell Cycle Arrest by Targeting Thioredoxin Reductase-1 in Human Prostate Cancer Cells.
    Yang M; Zhang W; Yu X; Wang F; Li Y; Zhang Y; Yang Y
    Med Sci Monit; 2021 Jun; 27():e930083. PubMed ID: 34125740
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Licochalcone a Induces ROS-Mediated Apoptosis through TrxR1 Inactivation in Colorectal Cancer Cells.
    Wu P; Yu T; Wu J; Chen J
    Biomed Res Int; 2020; 2020():5875074. PubMed ID: 32596335
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Selective killing of gastric cancer cells by a small molecule via targeting TrxR1 and ROS-mediated ER stress activation.
    Chen W; Zou P; Zhao Z; Weng Q; Chen X; Ying S; Ye Q; Wang Z; Ji J; Liang G
    Oncotarget; 2016 Mar; 7(13):16593-609. PubMed ID: 26919094
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Zebularine inhibits the growth of A549 lung cancer cells via cell cycle arrest and apoptosis.
    You BR; Park WH
    Mol Carcinog; 2014 Nov; 53(11):847-57. PubMed ID: 23661569
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Isobavachalcone Induces ROS-Mediated Apoptosis
    Li K; Zheng Q; Chen X; Wang Y; Wang D; Wang J
    Oxid Med Cell Longev; 2018; 2018():1915828. PubMed ID: 30410640
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Alantolactone promotes ER stress-mediated apoptosis by inhibition of TrxR1 in triple-negative breast cancer cell lines and in a mouse model.
    Yin C; Dai X; Huang X; Zhu W; Chen X; Zhou Q; Wang C; Zhao C; Zou P; Liang G; Rajamanickam V; Wang O; Zhang X; Cui R
    J Cell Mol Med; 2019 Mar; 23(3):2194-2206. PubMed ID: 30609207
    [TBL] [Abstract][Full Text] [Related]  

  • 7. EF24 induces ROS-mediated apoptosis via targeting thioredoxin reductase 1 in gastric cancer cells.
    Zou P; Xia Y; Chen W; Chen X; Ying S; Feng Z; Chen T; Ye Q; Wang Z; Qiu C; Yang S; Liang G
    Oncotarget; 2016 Apr; 7(14):18050-64. PubMed ID: 26919110
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inducing ubiquitination and degradation of TrxR1 protein by LW-216 promotes apoptosis in non-small cell lung cancer via triggering ROS production.
    Wang R; Zhong L; Wang T; Sun T; Yang J; Liu X; Wu Y; Guo Q; Gao Y; Zhao K
    Neoplasia; 2024 Jul; 53():101004. PubMed ID: 38733769
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Thimerosal, a competitive thioredoxin reductase 1 (TrxR1) inhibitor discovered via high-throughput screening.
    Ni Y; Luo Z; Lv Y; Ma S; Luo C; Du D
    Biochem Biophys Res Commun; 2023 Apr; 650():117-122. PubMed ID: 36780763
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Ethaselen synergizes with oxaliplatin in tumor growth inhibition by inducing ROS production and inhibiting TrxR1 activity in gastric cancer.
    Zhang H; Wu J; Yuan J; Li H; Zhang Y; Wu W; Chen W; Wang C; Meng S; Chen S; Huo M; He Y; Zhang C
    J Exp Clin Cancer Res; 2021 Aug; 40(1):260. PubMed ID: 34412665
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Curcumin analog WZ35 induced cell death via ROS-dependent ER stress and G2/M cell cycle arrest in human prostate cancer cells.
    Zhang X; Chen M; Zou P; Kanchana K; Weng Q; Chen W; Zhong P; Ji J; Zhou H; He L; Liang G
    BMC Cancer; 2015 Nov; 15():866. PubMed ID: 26546056
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Potent inhibition of gastric cancer cells by a natural compound via inhibiting TrxR1 activity and activating ROS-mediated p38 MAPK pathway.
    He W; Cao P; Xia Y; Hong L; Zhang T; Shen X; Zheng P; Shen H; Zhao Y; Zou P
    Free Radic Res; 2019 Jan; 53(1):104-114. PubMed ID: 30668191
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A thioredoxin reductase 1 inhibitor pyrano [3,2-a] phenazine inhibits A549 cells proliferation and migration through the induction of reactive oxygen species production.
    Ding Q; Wang H; Wang Y; Lu Y
    Mol Biol Rep; 2022 Sep; 49(9):8835-8845. PubMed ID: 35780225
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Carvacrol Induced Program Cell Death and Cell Cycle Arrest in Androgen-Independent Human Prostate Cancer Cells
    Khan F; Singh VK; Saeed M; Kausar MA; Ansari IA
    Anticancer Agents Med Chem; 2019; 19(13):1588-1608. PubMed ID: 31364516
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Discovery of novel hydroxyamidine based indoleamine 2,3-dioxygenase 1 (IDO1) and thioredoxin reductase 1 (TrxR1) dual inhibitors.
    Zhou J; Yu LZ; Fan YL; Guo CH; Lv XM; Zhou ZY; Huang HD; Miao DD; Zhang SP; Li XY; Zhao PP; Liu XP; Hu WH; Zhang C
    Eur J Med Chem; 2023 Jan; 245(Pt 1):114860. PubMed ID: 36370550
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Genistein induced anticancer effects on pancreatic cancer cell lines involves mitochondrial apoptosis, G
    Bi YL; Min M; Shen W; Liu Y
    Phytomedicine; 2018 Jan; 39():10-16. PubMed ID: 29433670
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Anticancer activity of Phloretin against the human oral cancer cells is due to G0/G1 cell cycle arrest and ROS mediated cell death.
    Yang G; Yin X; Ma D; Su Z
    J BUON; 2020; 25(1):344-349. PubMed ID: 32277653
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Increased Intracellular Reactive Oxygen Species Mediates the Anti-Cancer Effects of WZ35 via Activating Mitochondrial Apoptosis Pathway in Prostate Cancer Cells.
    Chen M; Zhou B; Zhong P; Rajamanickam V; Dai X; Karvannan K; Zhou H; Zhang X; Liang G
    Prostate; 2017 Apr; 77(5):489-504. PubMed ID: 27990666
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Curcuminoid B63 induces ROS-mediated paraptosis-like cell death by targeting TrxR1 in gastric cells.
    Chen X; Chen X; Zhang X; Wang L; Cao P; Rajamanickam V; Wu C; Zhou H; Cai Y; Liang G; Wang Y
    Redox Biol; 2019 Feb; 21():101061. PubMed ID: 30590310
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Lasalocid induces cytotoxic apoptosis and cytoprotective autophagy through reactive oxygen species in human prostate cancer PC-3 cells.
    Kim KY; Kim SH; Yu SN; Park SG; Kim YW; Nam HW; An HH; Yu HS; Kim YW; Ji JH; Seo YK; Ahn SC
    Biomed Pharmacother; 2017 Apr; 88():1016-1024. PubMed ID: 28178613
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.